32 completed, 7 terminated, 4 recruiting, 4 unknown. 51 Phase 2, 14 Phase 3, 6 Phase 1.
Follow Diclofenac: new trials by email Literature Review of Diclofenac trials Research Report on Diclofenac
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Topical Dexamethasone/Diclofenac Hydrogel for Postoperative Pain and Swelling in Facial Soft Tissue Injuries Poloxmer F-127 Hydrogel with Dexamethasone/Diclofenac, Plain Pluronic F-127 Hydrogel Placebo - Facial Injuries, Pain | Phase 2 / Phase 3 | Recruiting | Thamar University | 52 | 2026-01-01 | 2026-10-02 |
| Diclofenac for Prevention of Post-ERC Pancreatitis Diclofenac - Common Bile Duct Diseases | Phase 2 / Phase 3 | Not yet recruiting | Karolinska Institutet | 1000 | 2026-01-01 | 2025-08-13 |
| The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament Diclofenac Sodium, Calcium hydroxide - Endodontic Disease, Pulp Disease, Dental | Phase 2 / Phase 3 | Recruiting | British University In Egypt | 48 | 2025-11-01 | 2025-05-30 |
| Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent Immunotherapy Atezolizumab, Biospecimen Collection, Cemiplimab - Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma | Phase 2 | Recruiting | Emory University | 20 | 2025-04-09 | 2026-02-12 |
| Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease intra-nasal ketorolac, oral diclofenac - Post Operative Pain, Urolithiasis | Phase 1 / Phase 2 | Recruiting | University of Texas Southwestern Medical Center | 80 | 2025-03-01 | 2026-05-27 |
| Comparison of the Efficacy of Diclofenac Sodium and Subcutaneous 5% Dextrose Injection in Low Back Pain. 5% dextrose prolotherapy, Diclofenac 75mg/ml - Low Back Pain, Mechanical | Phase 1 / Phase 2 | Enrolling by invitation | Aksaray University Training and Research Hospital | 150 | 2024-07-15 | 2025-02-19 |
| Effect of Topical Diclofenac on Clinical Outcome in Breast Cancer Patients Treated With Capecitabine (CARBAMIDE®), (VOLTAREN®) Emulgel 1% - Hand and Foot Syndrome | Phase 2 | Completed | German University in Cairo | 86 | 2022-12-08 | 2024-01-03 |
| Treatment of Renal Colic in the Emergency Department: Comparison Between Magnesium Sulfate and Lidocaine. Magnesium sulfate and diclofenac, Lidocain and diclofenac, Placebo and diclofenac - Renal Colic | Phase 2 | Completed | University of Monastir | 800 | 2022-11-20 | 2023-09-21 |
| Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain Sustained Acoustic Device with 2.5% Diclofenac Patch, 1% Diclofenac Topical Gel - Knee Osteoarthritis | Phase 1 / Phase 2 | Completed | ZetrOZ, Inc. | 60 | 2021-08-01 | 2025-05-02 |
| Topical Diclofenac and Topical DFMO Chemoprevention Trial in Subjects With a History of Skin Cancer Solaraze and Vaniqa - Non-melanoma Skin Cancer | Phase 2 | Completed | University of Alabama at Birmingham | 64 | 2021-01-18 | 2025-12-17 |
| Bioequivalence Study to Compare Diclofenac Potassium Coated Tablet Versus Cataflam® 50 Coated Tablet Diclofenac Potassium coated tablet (50 mg Diclofenac Potassium), Cataflam® 50 coated tablet - Non-steroidal Anti-inflammatory (NSAID), Analgesic | Phase 1 / Phase 2 | Completed | Humanis Saglık Anonim Sirketi | 36 | 2020-08-25 | 2023-12-13 |
| Effectiveness and Safety of Sphaeralcea Angustifolia Standardized Extract as a Topical Treatment of Knee Osteoarthritis Standardized extract of Sphaeralcea angustifolia, Diclofenac Sodium Gel - Knee Osteoarthritis | Phase 2 | Unknown | Coordinación de Investigación en Salud, Mexico | 100 | 2020-07-10 | 2020-08-13 |
| Systemic Uptake of Diclofenac Sodium in Combination With Miconazole as Antifungal Nail Gel When Applied Daily With Monitoring of Hepatic and Renal Enzymes, and Serum Levels of Diclofenac 12 Hours After Application, and at 3 and 6 Months Study Antifungal Nail Gel Study - Tinea Unguium, Onychomycosis | Phase 2 | Unknown | William N Handelman | 30 | 2020-05-01 | 2020-04-10 |
| Study to Evaluate Arthroplasty Specimens for Osteoarthritis of the Knee and Hip Fasinumab, Naproxen, Diclofenac - Osteoarthritis, Knee, Osteoarthritis, Hip | Phase 2 | Terminated | Regeneron Pharmaceuticals | 23 | 2019-04-08 | 2023-10-17 |
| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Evaluation of RPH-104 Administered at Different Doses to Patients With Acute Gout Attack RPH - 104, Voltaren® - Gout Attack | Phase 2 | Terminated | R-Pharm | 47 | 2018-03-26 | 2022-07-25 |
| Sahastara Remedy Extract Capsule in Primary Osteoarthritis of Clinical Trial Phase II Sahastara remedy extract, Diclofenac - Osteoarthritis | Phase 2 | Unknown | Mr NARIN KAKATUM | 80 | 2018-01-01 | 2020-10-19 |
| Topical Chemoprevention of Skin Cancer Biomarkers topical diclofenac daily, placebo - Non-melanoma Skin Cancer | Phase 2 | Completed | University of Alabama at Birmingham | 24 | 2017-10-25 | 2026-01-21 |
| Lidocaine Infusion in Hystroscopy Lidocaine Hydrochloride, Diclofenac Sodium - Pain | Phase 2 | Completed | Ain Shams University | 44 | 2017-08-01 | 2020-01-28 |
| Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1 Diclofenac Sodium, Saline Solution - Neurofibromatosis 1, Cutaneous Neurofibroma | Phase 2 | Completed | Fundação Educacional Serra dos Órgãos | 7 | 2017-02-15 | 2017-10-26 |
| Comparative Study Between the Effect of Diclofanic and Ketorolac in Post Tonsillectomy Pain Management diclofenac, ketorolac - Pain, Acute | Phase 2 / Phase 3 | Completed | Assiut University | 100 | 2017-01-31 | 2020-07-14 |
Showing 20 of 51. Sign in to see all of them.
Pain (7) · Osteoarthritis (5) · Osteoarthritis, Knee (5) · Pain, Postoperative (5) · Acute Pain (3) · Arthritis (2) · Inflammation (2) · Pulpitis (2) · Renal Colic (2) · Agnosia (1) · Ankle Injuries (1) · Arthralgia (1) · Arthritis, Gouty (1) · Breast Neoplasms (1) · Bursitis (1)
Cairo University (4) · Assiut University (2) · Cerimon Pharmaceuticals (2) · University of Alabama at Birmingham (2) · University of Monastir (2) · Aga Khan University (1) · Ain Shams University (1) · Aksaray University Training and Research Hospital (1) · Atrium Innovations (1) · Baskent University (1) · British University In Egypt (1) · Clinical Research Centre, Malaysia (1) · Coordinación de Investigación en Salud, Mexico (1) · Emory University (1) · Fundação Educacional Serra dos Órgãos (1)
United States (13) · Egypt (9) · United Kingdom (3) · India (2) · Mexico (2) · Thailand (2) · Tunisia (2) · Brazil (1) · Chile (1) · Germany (1) · Israel (1) · Jordan (1) · Netherlands (1) · Pakistan (1) · Poland (1)
Dan Levitt, MD (2) · Alejandro Arce-Salinas, M.D. (1) · Amatallah H Al-Rawhani, Pos (1) · Amatallah H Al-Rawhani, Postgraduate (1) · Associate Professor Arunporn Itharat, Ph.D. (1) · Brett Johnson, MD (1) · Carlos Molina-Calzada, M.D. (1) · Chang-Chieh Wu, MD (1) · Craig Elmets, MD (1) · Craug Elmets, MD (1) · David Jimenez, MD, PhD (1) · Dilip Khambete, MDS (1) · Dr. Suzan AW Amin, PhD (1)
PMID 10352050, PMID 10613619, PMID 12148679, PMID 12917995, PMID 15230906, PMID 15507941, PMID 15798411, PMID 16321158, PMID 17196714, PMID 17437870, PMID 18498882, PMID 23440827, PMID 26506138, PMID 26712942, PMID 26852833, PMID 27080115, PMID 28197031, PMID 29202646, PMID 29247809, PMID 33817379, PMID 9594474
2018 (1), P01CA027502 (1), P30CA023074 (1), P30CA138292 (1), R01CA193885 (1)