20 completed, 2 terminated, 1 active not recruiting. 16 Not applicable, 3 Phase 1, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Completed 14, Active not recruiting 1, Terminated 1 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Phase 4 | 1 | Completed 1 |
Follow Water Pipe Smoking: new trials by email Literature Review of Water Pipe Smoking trials Research Report on Water Pipe Smoking
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Developing and Pilot Testing an Intervention to Reduce Household Shisha Smoke Exposure Within Somali Homes CHW-delivered intervention - Shisha | Not applicable | Completed | University of Minnesota | 15 | 2025-09-03 | 2026-03-18 |
| Oxidative DNA Damage Enhancement by Vitamin C Among Narghile Smokers and Non-smokers Vitamin C (Ascorbic Acid) regularly has been taken - Narghile | Not applicable | Completed | Nora Tariq Mohammed | 96 | 2024-10-15 | 2025-08-26 |
| Developing and Testing Waterpipe-specific Health Warning Labels Test Health Warning Label (HWL), Test without Health Warning Label (no-HWL) - Waterpipe Smoking, Health Warning Label | Not applicable | Completed | Florida International University | 44 | 2022-10-03 | 2024-12-10 |
| Secondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol Combustible Hookah Smoke, Electronic Hookah Aerosol, Clean Room Air - Hookah Smoking, Secondhand Aerosol | Not applicable | Active not recruiting | University of California, Los Angeles | 12 | 2021-06-25 | 2026-04-22 |
| Effect of Waterpipe Smoking on Periodontal Health Waterpipe Smoking, Periodontal Diseases | Completed | Noha Ayman Ghallab | 323 | 2020-11-01 | 2022-03-11 | |
| Reactions to Warnings on Hookah Ads Ads Only, Ads with text-only health warning labels (HWLs), Ads with text + graphic health warning labels (HWLs) - Reactions to Warnings, Hookah Smoking | Not applicable | Completed | Duke University | 2588 | 2018-10-05 | 2025-12-18 |
| Optimizing Risk Messages for Waterpipe Tobacco Cessation in Young Adults Hookah tobacco risk messages - Hookah Smoking | Not applicable | Completed | Georgetown University | 349 | 2018-08-28 | 2021-10-20 |
| Assessing Toxicity of Waterpipe Tobacco Smoking Differential effects of waterpipe smoking practices on toxicity of waterpipe tobacco smoke - Waterpipe Smoking | Not applicable | Completed | San Diego State University | 85 | 2017-10-20 | 2025-04-09 |
| The Impact of Waterpipe Tobacco Flavors on Waterpipe Smoking Intentions, Perceptions, Patterns, and Toxicant Exposure Flavored-Sweetened Waterpipe Tobacco, Unflavored-sweetened waterpipe tobacco, Unflavored-very low sweetened waterpipe tobacco - Smoking, Hookah, Waterpipe Smoking | Not applicable | Completed | University of Oklahoma | 91 | 2017-06-01 | 2019-06-24 |
| Evaluation of a Brief Tobacco Intervention in the US Military BTI, Cigarette smoking military tailored pamphlet, Standard smoking cessation intervention - Tobacco Use, Tobacco Smoking | Not applicable | Completed | University of Virginia | 2999 | 2017-04-05 | 2021-10-07 |
| Understanding the Effect of Flavor on Hookah Smoking Experience Flavored tobacco, Non-flavored tobacco - Waterpipe Smoking | Not applicable | Completed | Florida International University | 144 | 2017-03-21 | 2020-08-03 |
| Effect of Concurrent Hookah and Alcohol Consumption on Smoking Topography and Toxicant Exposure Active alcohol consumption, Placebo consumption - Alcohol Use, Unspecified, Hookah Smoking | Not applicable | Completed | Oklahoma State University | 50 | 2017-02-22 | 2017-10-13 |
| Varenicline (Chantix) Treatment for Waterpipe Smoking Cessation Varinecline (Chantix), Placebo (for Varenicline), Behavioral Therapy - Nicotine Dependence | Phase 4 | Completed | American University of Beirut Medical Center | 152 | 2016-08-31 | 2021-03-17 |
| Acute Effects of Waterpipe Smoking on Cognitive Measures and Cardiorespiratory Parameters The Digit span test and PASAT with waterpipe smoking, The Digit span test and PASAT without waterpipe smoking - Waterpipe Smoking | Not applicable | Completed | Rambam Health Care Campus | 55 | 2016-08-01 | 2018-08-10 |
| Effects of Hookah (Waterpipe) Smoking on Blood Vessel Function Hookah smoking - Hookah Smoking | Not applicable | Terminated | Cedars-Sinai Medical Center | 58 | 2015-01-01 | 2021-02-04 |
| Effects of Nicotine-Free Hookah Smoking on Blood Flow to the Heart, Muscle and Skin Nicotine free hookah smoking - Nicotine-free Hookah Smoking | Phase 1 / Phase 2 | Terminated | Cedars-Sinai Medical Center | 9 | 2014-11-01 | 2020-01-13 |
| The Role of Contingency Management in Waterpipe Smoking Cessation Contingency Management - Waterpipe Smoking | Not applicable | Completed | Washington State University | 39 | 2014-07-01 | 2015-12-14 |
| Effects of Hookah Smoking on Blood Flow to the Heart, Muscle and Skin Hookah smoking - Hookah Smoking | Not applicable | Completed | Cedars-Sinai Medical Center | 42 | 2013-03-01 | 2020-01-13 |
| Efficacy of School-Based, Peer-Led Asthma and Smoking Prevention Program on CO1 Levels and Smoking Behavior Among Early Adolescents in Jordan TAJ Plus (Adolescent Asthma Action in Jordan) Plus the added class smoke free pledge - Asthma, Tobacco | Phase 2 | Completed | University of Technology, Sydney | 815 | 2012-10-01 | 2013-09-10 |
| Carbon Monoxide and Oxidative Stress in Waterpipe Smokers Breath carbon monoxide, Pulmonary function tests., Oxidative stress and antioxidant status. - Waterpipe Smoking, Oxidative Stress | Not applicable | Completed | Ataturk Training and Research Hospital | 100 | 2012-07-01 | 2016-10-18 |
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Smoking Cessation (4) · Smoking (3) · Tobacco Use Disorder (2) · Alcohol Drinking (1) · Asthma (1) · Cigar Smoking (1) · Cigarette Smoking (1) · Health Risk Behaviors (1) · Periodontal Diseases (1) · Pipe Smoking (1) · Tobacco Smoking (1) · Tobacco Use (1) · Vaping (1)
Behavior (23) · Pipe Smoking (22) · Smoking (20) · Health Behavior (4) · Chemically-Induced Disorders (2) · Mental Disorders (2) · Substance-Related Disorders (2) · Bronchial Diseases (1) · Drinking Behavior (1) · Hypersensitivity (1) · Hypersensitivity, Immediate (1) · Immune System Diseases (1) · Lung Diseases (1) · Lung Diseases, Obstructive (1) · Mouth Diseases (1)
Smoking Water Pipes (3) · Ascorbic Acid (1) · Behavior Therapy (1) · Economics (1) · Ethanol (1) · Exercise (1) · Oxidative Stress (1) · Respiratory Physiological Phenomena (1) · Tobacco Products (1) · Varenicline (1)
Cedars-Sinai Medical Center (3) · Florida International University (2) · Rambam Health Care Campus (2) · American University of Beirut Medical Center (1) · Ataturk Training and Research Hospital (1) · Duke University (1) · Georgetown University (1) · Noha Ayman Ghallab (1) · Nora Tariq Mohammed (1) · Oklahoma State University (1) · San Diego State University (1) · University of California, Los Angeles (1) · University of California, San Francisco (1) · University of Memphis (1) · University of Minnesota (1)
United States (15) · Israel (2) · Egypt (1) · Iraq (1) · Lebanon (1) · Syria (1)
April Wilhelm, MD, MPH (1) · Darren Mays, PhD, MPH (1) · Florian Rader, MD (1) · Isaac Lipkus, PhD (1) · Kawkab Shishani, PhD (1) · Kenneth D. Ward, PhD (1) · Lea Bentur, Prof (1) · Lea Bentur, Prof. (1) · Nada Kassem, DrPH (1) · Neal L Benowitz, MD (1) · Noha Ayman Ghallab, MD (1) · Ozcan Erel, Prof. M.D. (1) · Ronald G Victor (1) · Ronald G Victor, MD (1) · Theodore Wagener, PhD (1)
PMID 24158379, PMID 12235470, PMID 15564614, PMID 15970733, PMID 16274311, PMID 18030938, PMID 20457679, PMID 20888700, PMID 21030492, PMID 21908725, PMID 25666550, PMID 25997893, PMID 26383198, PMID 29963753, PMID 30764644, PMID 30820567, PMID 31326957, PMID 31903494
R01CA217861 (1), R03DA041928 (1)