8 completed, 2 unknown, 1 not yet recruiting, 1 terminated. 12 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 8, Unknown 2, Not yet recruiting 1, Terminated 1 |
| Phase 2 | 2 | Not yet recruiting 1, Terminated 1 |
Follow Vulvodynia: new trials by email Literature Review of Vulvodynia trials Research Report on Vulvodynia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of Topical Testosterone and Estrogen vs Estrogen Alone in Vulvodynia: a Randomized Controlled Trial Estradiol 0.01% Vag Cream, testosterone 0.1% and estradiol 0.01% vaginal cream - Vulvodynia, Dyspareunia | Phase 2 / Phase 3 | Not yet recruiting | TriHealth Inc. | 44 | 2025-12-01 | 2025-12-03 |
| Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery Bupivacaine-Meloxicam - Stress Urinary Incontinence, Surgical Incision | Phase 3 | Completed | TriHealth Inc. | 148 | 2023-01-23 | 2024-11-22 |
| Physical Therapy as Adjuvant Treatment of Vulvodynia: a Randomized Controled Trial Amitriptyline, Kinesiotherapy, IC (Quark) - Vulvodynia | Phase 3 | Unknown | University of Campinas, Brazil | 58 | 2016-07-01 | 2016-08-18 |
| Botulinum Toxin A as a Treatment for Provoked Vestibulodynia botulinum toxin A, NaCl - Vulvodynia | Phase 3 | Completed | Karolinska Institutet | 90 | 2016-05-15 | 2019-08-15 |
| Placebo-controlled RCT of Botulinum Toxin A as a Treatment for Provoked Vestibulodynia Botulinum Toxin Type A, Sterile Saline Solution - Vulvodynia | Phase 3 | Completed | Karolinska Institutet | 90 | 2016-05-01 | 2019-08-14 |
| A Study of the Effects of Topical Capsaicin in the Treatment of Provoked Vestibulodynia Capsaicin patch - Vestibulodynia | Phase 2 / Phase 3 | Terminated | Centre Hospitalier Universitaire de Besancon | 10 | 2016-01-20 | 2022-11-14 |
| Clobetasol Propionate Versus Fractionated Carbon Dioxide Laser for the Treatment of Lichen Sclerosus Fractionated Carbon Dioxide Laser, Clobetasol Propionate 0.05% ointment - Vulvar Lichen Sclerosus | Phase 3 | Completed | Medstar Health Research Institute | 52 | 2015-10-01 | 2021-10-12 |
| Dysbiosis in Localized Provoked Vulvodynia (LPV) Low Oxalate Diet - Vulvodynia, Vulvar Vestibulitis | Phase 3 | Unknown | Western Galilee Hospital-Nahariya | 70 | 2015-03-01 | 2015-03-20 |
| Therapy to Prevent Sexual Pain in Breast Cancer Survivors Topical liquid lidocaine, Topical saline - Vulvodynia, Dyspareunia | Phase 3 | Completed | OHSU Knight Cancer Institute | 50 | 2011-12-01 | 2017-04-14 |
| Savella in Treatment for Provoked Vestibulodynia Milnacipran - Vestibulodynia, Vulvodynia | Phase 3 | Completed | University of Tennessee | 31 | 2010-10-01 | 2018-06-11 |
| A Pilot Study of the Effects of Botulinum Toxin in the Treatment of Provoked Vestibulodynia Botulinum Toxin Type A, Saline solution, Indexes - Vestibulodynia | Phase 3 | Completed | Centre Hospitalier Universitaire de Besancon | 60 | 2010-05-04 | 2022-11-10 |
| Efficacy Study of Topical Application of Nifedipine Cream to Treat Vulvar Vestibulitis Nifedipine cream topical application - Vulvar Diseases, Vulvar Pain | Phase 3 | Completed | Western Galilee Hospital-Nahariya | 30 | 2006-04-01 | 2008-05-08 |
Dyspareunia (2) · Vulvar Lichen Sclerosus (2) · Breast Neoplasms (1) · Lichen Sclerosus et Atrophicus (1) · Surgical Wound (1) · Urinary Incontinence, Stress (1) · Vulvar Diseases (1) · Vulvar Vestibulitis (1)
Female Urogenital Diseases (12) · Female Urogenital Diseases and Pregnancy Complications (12) · Genital Diseases (12) · Genital Diseases, Female (12) · Urogenital Diseases (12) · Vulvar Diseases (11) · Male Urogenital Diseases (3) · Genital Diseases, Male (2) · Mental Disorders (2) · Sexual Dysfunction, Physiological (2) · Sexual Dysfunctions, Psychological (2) · Skin Diseases (2) · Skin and Connective Tissue Diseases (2) · Breast Diseases (1) · Lichenoid Eruptions (1)
Botulinum Toxins, Type A (3) · Sodium Chloride (2) · Amitriptyline (1) · Clobetasol (1) · Estradiol (1) · Milnacipran (1) · Ointments (1) · Saline Solution (1) · Testosterone (1) · Vaginal Creams, Foams, and Jellies (1) · Water (1) · bupivacaine-meloxicam drug combination (1)
Centre Hospitalier Universitaire de Besancon (2) · Karolinska Institutet (2) · TriHealth Inc. (2) · Western Galilee Hospital-Nahariya (2) · Medstar Health Research Institute (1) · OHSU Knight Cancer Institute (1) · University of Campinas, Brazil (1) · University of Tennessee (1)
United States (5) · France (2) · Sweden (2) · Brazil (1) · Israel (1)
Fabien Pelletier, MD (2) · Jacob Bornstein, MD (2) · Nina Bohm-Starke, MD (2) · Candace S Brown, PharmD (1) · Cheryl Iglesia, MD (1) · Doron Zarfati, MD (1) · Marcela G Bardin, PT, Master (1) · Martha Goetsch, MD (1) · Paulo C Giraldo, MD, PhD (1)
PMID 17012991, PMID 18981976, PMID 20059663, PMID 24807329, PMID 26215946, PMID 27045258, PMID 27150263, PMID 32769643, PMID 33957642, PMID 35943448, PMID 36307361, PMID 36951987
2016 (1)