13 completed, 5 unknown, 4 recruiting, 2 not yet recruiting. 12 Not applicable, 4 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 8, Unknown 2, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 4 | Completed 2, Active not recruiting 1, Not yet recruiting 1 |
| Phase 3 | 3 | Completed 2, Recruiting 1 |
Follow Lichen Sclerosus et Atrophicus: new trials by email Literature Review of Lichen Sclerosus et Atrophicus trials Research Report on Lichen Sclerosus et Atrophicus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nemolizumab for LS Nemolizumab 30 mg - Lichen Sclerosus of Vulva | Phase 2 | Not yet recruiting | University of Texas Southwestern Medical Center | 25 | 2026-09-01 | 2026-07-15 |
| A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen Sclerosus Delgocitinib, Cream Vehicle - Lichen Sclerosus | Phase 3 | Recruiting | LEO Pharma | 652 | 2026-05-01 | 2026-10-13 |
| Efficacy of Collagendep in Reducing Vulvar Dryness in Patients With Lichen Sclerosus Treated With Fat Grafting Autologous Fat Grafting (Lipofilling), Collagendep Pink Beauty - Vulvar Lichen Sclerosus, Vulvar Atrophy | Not applicable | Not yet recruiting | San Gallicano Dermatological Institute IRCCS | 40 | 2026-02-20 | 2026-03-04 |
| Identification of Genetic Variants Associated With Lichen Sclerosus No Interventions - Lichen Sclerosus Lesion | Recruiting | Gudula Kirtschig | 100 | 2025-12-13 | 2026-07-22 | |
| Male Lichen Sclerosus - Risk Factors, Treatment, and Impact on Quality of Life Circumcision - Lichen Sclerosus | Recruiting | Region Västerbotten | 300 | 2025-10-06 | 2026-02-10 | |
| Topical Ruxolitinib Evaluation in Immune-related Vitiligo-like Depigmentation Ruxolitinib Topical Cream - Immune-related Vitiligo-like-Depigmentation | Phase 2 | Active not recruiting | University of Zurich | 34 | 2024-07-25 | 2026-07-24 |
| Vaginal Ecosystem and Network in the United States Study Vaginal Swab Collection - Bacterial Vaginosis, Candidiasis | Enrolling by invitation | Vaginal Biome Science | 3250 | 2024-05-16 | 2025-07-01 | |
| Comparison of Laser Treatment With Clobetasol Therapy in Patients With Lichen Sclerosus Treatment with Monalisa Glide Laser, Treatment with Clobetasol - Lichen Sclerosus | Not applicable | Recruiting | Kantonsspital Winterthur KSW | 120 | 2023-11-10 | 2025-09-23 |
| A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Lichen Sclerosus Ruxolitinib cream, Vehicle cream - Lichen Sclerosus | Phase 2 | Completed | Incyte Corporation | 61 | 2022-11-18 | 2024-09-24 |
| Genital Lichen Sclerosus - Epidemiology, Comorbidities and the Role of Vulvar and Penile Microbiome Lichen Sclerosus | Unknown | Region Jönköping County | 200 | 2022-01-14 | 2023-01-09 | |
| Laser vs Clobetasol for Lichen Sclerosus Clobetasol 0.05% Emollient Top Cream, Non-ablative CO2 Laser - Lichen Sclerosus | Phase 3 | Completed | Ruhr University of Bochum | 246 | 2021-11-02 | 2025-12-04 |
| Laser Therapy in Women With Lichenoid Disorders Laser, Placebolaser - Lichen Sclerosus Et Atrophicus, Lichen Planus | Not applicable | Completed | Medical University of Graz | 40 | 2020-11-17 | 2025-05-13 |
| Effect of Treatment With the Ablative Fractional Carbodioxide Laser in Vulvar Lichen Sclerosis Active microablative fractional CO2 laser designed as SmartXide Touch C60, CO2 laser system for MonaLisa Touch, DEKA, Florence, Sham microablative fractional CO2 laser designed as SmartXide Touch C60, CO2 laser system for MonaLisa Touch, DEKA, Florence - Lichen Sclerosus Et Atrophicus of the Vulva | Not applicable | Unknown | Insel Gruppe AG, University Hospital Bern | 64 | 2020-01-01 | 2021-08-19 |
| Safety and Efficacy of Laser Therapy in Gynaecology Herpes Genitalis, Genital Wart | Unknown | Juna d.o.o. | 300 | 2019-07-24 | 2019-08-30 | |
| MonaLisa Touch Laser for the Treatment of Vulvar Lichen Sclerosus FxCO2 Laser, Sham Laser - Lichen Sclerosus | Not applicable | Completed | Center for Vulvovaginal Disorders | 40 | 2018-08-28 | 2020-11-12 |
| a Flexible Wound Dressing for the Management of Genital Skin Conditions Film forming silicone gel (7-0940) - Vaginitis, Atrophic Vaginitis | Not applicable | Completed | Stratpharma AG | 54 | 2018-01-31 | 2022-05-31 |
| Lichen Sclerosus - the Influence on Quality of Life Standard care and sexological counseling - Lichen Sclerosus | Not applicable | Completed | Regionshospital Nordjylland | 158 | 2018-01-04 | 2020-05-27 |
| Efficacy and Safety of the Neodymium Laser in Treatment of Urogenital Tract Diseases in Women Genitourinary Syndrome of Menopause, Pelvic Floor Dysfunction | Completed | 1st Federal Budgetary Healthcare Institution Volga District Medical Center | 60 | 2018-01-01 | 2022-02-22 | |
| Biomarkers of Lichen Sclerosus Lichen Sclerosus | Unknown | Center for Vulvovaginal Disorders | 58 | 2017-11-27 | 2018-06-19 | |
| Fractional / Pixel CO2 Laser Treatment of Vulvar Atrophy and Lichen Sclerosus Fractional / Pixel CO2 Laser - Vaginal Atrophy, Lichen Sclerosus | Not applicable | Completed | Hadassah Medical Organization | 16 | 2017-09-01 | 2019-08-06 |
Showing 20 of 29. Sign in to see all of them.
Vulvar Lichen Sclerosus (6) · Lichen Planus (5) · Vulvar Diseases (4) · Vulvodynia (4) · Neoplasms (2) · Vulvar Neoplasms (2) · Atrophic Vaginitis (1) · Candidiasis (1) · Carcinoma, Squamous Cell (1) · Condylomata Acuminata (1) · Disease (1) · Endometriosis (1) · Herpes Genitalis (1) · Hidradenitis Suppurativa (1)
Lichenoid Eruptions (29) · Skin Diseases, Papulosquamous (29) · Skin and Connective Tissue Diseases (29) · Skin Diseases (28) · Female Urogenital Diseases (13) · Female Urogenital Diseases and Pregnancy Complications (13) · Genital Diseases (13) · Genital Diseases, Female (13) · Urogenital Diseases (13) · Vulvar Diseases (7) · Male Urogenital Diseases (3) · Bacterial Infections (2) · Bacterial Infections and Mycoses (2) · Genital Diseases, Male (2) · Genital Neoplasms, Female (2)
Clobetasol (4) · Circumcision, Male (1) · Lasers (1) · Lasers, Solid-State (1) · Ointments (1) · Photography (1) · Standard of Care (1) · Therapeutics (1) · delgocitinib (1) · nemolizumab (1) · pimecrolimus (1) · ruxolitinib (1)
Center for Vulvovaginal Disorders (5) · Northwestern University (2) · 1st Federal Budgetary Healthcare Institution Volga District Medical Center (1) · Dr Adolf Lukanovič (1) · Ginekološka Poliklinika Dr. Vesna Harni (1) · Gloucestershire Hospitals NHS Foundation Trust (1) · Gudula Kirtschig (1) · Hadassah Medical Organization (1) · Incyte Corporation (1) · Insel Gruppe AG, University Hospital Bern (1) · Juna d.o.o. (1) · Kantonsspital Winterthur KSW (1) · LEO Pharma (1) · Medical University of Graz (1) · Medstar Health Research Institute (1)
United States (11) · Switzerland (4) · Canada (3) · Sweden (2) · United Kingdom (2) · Australia (1) · Austria (1) · Croatia (1) · Denmark (1) · Germany (1) · Israel (1) · Russia (1) · Slovenia (1)
Andrew T Goldstein, MD (3) · Bethanee J Schlosser, MD, PhD (2) · Andrew Goldstein, MD (1) · Annika Bergman, PhD (1) · Charles Macri, MD (1) · Cheryl Iglesia, MD (1) · Clemens B Tempfer, MD (1) · Gesine Meili, MD (1) · Gudula Kirtschig, Dr. (1) · Haq Nawaz, MD (1) · Kimberly Capone, PhD (1) · Laura Knabben, Dr. med. (1)
PMID 12418071, PMID 15568399, PMID 16130842, PMID 16176512, PMID 20522071, PMID 20868406, PMID 21353334, PMID 25608255, PMID 33957642, PMID 33957648, PMID 35333024, PMID 39035147, PMID 42208069
2023 (1), 2025 (1)