26 completed. 26 Phase 1, 17 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 26 | Completed 26 |
| Phase 2 | 17 | Completed 17 |
Follow Vision Disorders: new trials by email Literature Review of Vision Disorders trials Research Report on Vision Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patient-centered Modular CBT for CPTSD: A Randomised Controlled Pilot Study Psychotherapy - Complex Post-Traumatic Stress Disorder | Phase 1 / Phase 2 | Completed | Danish Veterans Centre | 60 | 2021-01-05 | 2025-04-02 |
| Safety and Efficacy of NPI-001 Tablets for RP Associated With Usher Syndrome NPI-001, Placebo - Usher Syndromes | Phase 1 / Phase 2 | Completed | Nacuity Pharmaceuticals, Inc. | 49 | 2020-09-03 | 2026-07-01 |
| Gene Therapy for Achromatopsia (CNGA3) adeno-associated virus vector AAV- CNGA3 - Achromatopsia | Phase 1 / Phase 2 | Completed | MeiraGTx UK II Ltd | 11 | 2019-08-12 | 2022-12-01 |
| Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene QR-421a, Sham-procedure (dose cohort 1&2 only) - Retinitis Pigmentosa, Usher Syndrome Type 2 | Phase 1 / Phase 2 | Completed | ProQR Therapeutics | 20 | 2019-03-06 | 2022-04-20 |
| ADVM-022 Intravitreal Gene Therapy for Wet AMD ADVM-022 - Wet Age-related Macular Degeneration, Neovascular Age-related Macular Degeneration | Phase 1 | Completed | Adverum Biotechnologies, Inc. | 30 | 2018-11-14 | 2023-08-08 |
| Side Effects of Atropine (SEA) Study 0.01% concentration atropine drops - Myopia | Phase 1 / Phase 2 | Completed | Jeffrey J. Walline, OD PhD | 31 | 2018-07-23 | 2022-12-02 |
| Gene Therapy for Achromatopsia (CNGB3) AAV - CNGB3 - Achromatopsia | Phase 1 / Phase 2 | Completed | MeiraGTx UK II Ltd | 23 | 2017-01-16 | 2023-03-08 |
| A Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram Syndrome dantrolene sodium - Wolfram Syndrome, Diabetes Mellitus | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 21 | 2017-01-01 | 2024-03-13 |
| Pilot Clinical Evaluation of Approved Contact Lenses Marketed Contact Lens 1, Marketed Contact Lens 2, Marketed Contact Lens 3 - Vision Disorders | Phase 1 | Completed | Johnson & Johnson Vision Care, Inc. | 30 | 2015-08-01 | 2017-06-20 |
| Safety Study of TPI-287 to Treat CBS and PSP TPI 287 2 mg/m2, TPI-287 20 mg/m2, Placebo - Primary Four Repeat Tauopathies (4RT), Corticobasal Syndrome (CBS) | Phase 1 | Completed | University of California, San Francisco | 44 | 2014-05-01 | 2020-04-15 |
| Study to Determine the Efficacy and Safety of ELS-M11 in Acute Migraine ELS-M11, Placebo - Migraine Headaches | Phase 1 / Phase 2 | Completed | Achelios Therapeutics | 48 | 2014-03-01 | 2017-07-11 |
| Nitisinone for Type 1B Oculocutaneous Albinism Nitisinone - Albinism, Vision Loss | Phase 1 / Phase 2 | Completed | National Eye Institute (NEI) | 5 | 2013-04-16 | 2019-02-26 |
| Combined tDCS and Vision Restoration Training in Post-acute Stroke: an Exploratory Efficacy and Safety Study verum tDCS, sham tDCS, VRT - Hemianopia, Stroke | Phase 1 / Phase 2 | Completed | University of Magdeburg | 19 | 2013-03-01 | 2016-03-09 |
| Combined tDCS and Vision Restoration Training in Subacute Stroke Rehabilitation: A Pilot Study tDCS, Standard rehabilitation - Hemianopia, Stroke | Phase 1 / Phase 2 | Completed | University of Magdeburg | 14 | 2013-01-01 | 2016-10-17 |
| Treatment of Residual Amblyopia With Donepezil Donepezil, Patching - Amblyopia | Phase 1 | Completed | Boston Children's Hospital | 18 | 2012-08-01 | 2021-06-18 |
| CNTF Implants for CNGB3 Achromatopsia NT-501 CNTF-releasing implant - Eye Disease, Achromatopsia | Phase 1 / Phase 2 | Completed | National Eye Institute (NEI) | 5 | 2012-07-01 | 2016-11-21 |
| Assessment of a New Surgical Smoke Clearing Technology in Laparoscopic Cholecystectomy Innervision Surgical Smoke Removal System - Focus: Surgical Smoke During Laparoscopic Surgery | Phase 1 / Phase 2 | Completed | Asalus Medical Instruments Limited | 30 | 2012-04-01 | 2012-08-15 |
| Intra-arterial Thrombolysis for Severe Recent Central Retinal Vein Occlusion Tissue Plasminogen Activator - Central Retinal Vein Occlusion | Phase 1 | Completed | Weill Medical College of Cornell University | 1 | 2012-01-01 | 2018-08-06 |
| Computer Vision System for the Blind Veteran initial system, modified system - Blindness | Phase 1 | Completed | VA Office of Research and Development | 16 | 2011-11-01 | 2016-01-22 |
| Comparison of Photorefraction With Cycloautorefraction and Cycloretinoscopy at Emam Hosein Medical Centre in 2008-2009 photorefraction,cycloautorefraction,cycloretinoscopy - Amblyopia | Phase 1 / Phase 2 | Completed | Shahid Beheshti University of Medical Sciences | 2008-05-01 | 2010-04-08 |
Showing 20 of 26. Sign in to see all of them.
Amblyopia (5) · Color Vision Defects (5) · Blindness (3) · Eye Diseases (3) · Hemianopsia (2) · Macular Degeneration (2) · Macular Edema (2) · Photophobia (2) · Retinal Diseases (2) · Stroke (2) · Usher Syndromes (2) · Albinism (1) · Anisometropia (1) · Ataxia (1)
Nervous System Diseases (26) · Neurologic Manifestations (26) · Pathological Conditions, Signs and Symptoms (26) · Sensation Disorders (26) · Signs and Symptoms (26) · Eye Diseases (23) · Brain Diseases (10) · Central Nervous System Diseases (10) · Eye Diseases, Hereditary (9) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Blindness (5) · Cone Dystrophy (5) · Retinal Degeneration (5)
Transcranial Direct Current Stimulation (2) · Atropine (1) · Dantrolene (1) · Donepezil (1) · Intravitreal Injections (1) · Ketoprofen (1) · Psychotherapy (1) · Ranibizumab (1) · Rituximab (1) · TPI-287 (1) · Tissue Plasminogen Activator (1) · nitisinone (1)
National Eye Institute (NEI) (4) · MeiraGTx UK II Ltd (2) · University of Magdeburg (2) · Achelios Therapeutics (1) · Adverum Biotechnologies, Inc. (1) · Asalus Medical Instruments Limited (1) · Boston Children's Hospital (1) · City, University of London (1) · Danish Veterans Centre (1) · Jeffrey J. Walline, OD PhD (1) · Johnson & Johnson Vision Care, Inc. (1) · Nacuity Pharmaceuticals, Inc. (1) · ProQR Therapeutics (1) · Retina Research Foundation (1) · Shahid Beheshti University of Medical Sciences (1)
United States (18) · United Kingdom (4) · Austria (2) · Canada (2) · Germany (2) · Australia (1) · Denmark (1) · France (1) · Iran (1)
Adam Boxer, MD, PhD (1) · Agnes Wong, MD (1) · Bernhard A Sabel, Prof. Dr. (1) · Bharti Gangwani, MD (1) · Brian P Brooks, M.D. (1) · Carolyn Wu, MD (1) · Cha-Min Tang, PhD MD (1) · Craig A Elmets (1) · Crist J. Frangakis, Ph.D. (1) · David G. Hunter, MD, PhD (1) · Fumihiko Urano, MD (1) · Hong Jiang, MD, PhD (1) · James Bainbridge (1) · James Bainbridge, Prof (1) · Jared Torkington, MBBS MS FRCS (1)
PMID 17855283, PMID 20212198, PMID 23882695, PMID 25205868, PMID 28082176, PMID 30674731, PMID 31215818, PMID 31710340, PMID 34185708, PMID 37172884, PMID 37418643, PMID 38152412
2016 (1), 2018 (1), R21DK113487 (1)