12 completed, 4 terminated, 2 recruiting, 2 unknown. 14 Not applicable, 4 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 7, Recruiting 2, Terminated 2, Unknown 2, Withdrawn 1 |
| Phase 3 | 4 | Completed 3, Terminated 1 |
| Phase 2 | 3 | Terminated 2, Completed 1 |
Follow Vestibulodynia: new trials by email Literature Review of Vestibulodynia trials Research Report on Vestibulodynia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Does a Virtual Program for Pelvic Pain Improve Pain and Sexual Outcomes in Individuals With Provoked Vestibulodynia? Virtual online pelvic health program - Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis | Not applicable | Recruiting | Queen's University | 250 | 2025-12-17 | 2026-02-12 |
| VIBRating vs Traditional Therapy for Treatment of ENTry Dyspareunia Pelvic floor therapy - Genito-Pelvic Pain/Penetration Disorder, Dyspareunia | Not applicable | Recruiting | Medstar Health Research Institute | 60 | 2025-03-01 | 2025-05-21 |
| Treatment and Mapping of Impostor Phenomenon Impostor tasks - Dermatoses, Vestibulodynia | Not applicable | Unknown | Umeå University | 20 | 2024-05-15 | 2024-05-10 |
| Effects of Flourish HEC on Localized Provoked Vulvodynia BioNourish, a component of the Flourish HEC kit, Control - no intervention - Vulvodynia, Vestibulodynia | Not applicable | Completed | Vaginal Biome Science | 7 | 2022-09-26 | 2024-02-06 |
| Feasibility Study for Provoked Vestibulodynia Somatosensory Rehabilitation Program, Educational Pain Management Program - Vestibulodynia | Not applicable | Completed | Université de Sherbrooke | 45 | 2022-05-16 | 2023-09-28 |
| Somatocognitive Therapy in Treatment of Provoked (Localized) Vestibulodynia - Randomized Clinical Trial (ProLoVe Study) Somatocognitive physiotherapy, Treatment as usual - Vulvodynia, Vestibulodynia | Not applicable | Unknown | Oslo Metropolitan University | 128 | 2021-01-01 | 2022-09-21 |
| Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments 5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline, Placebo cream - Vestibulodynia, Temporomandibular Disorder | Phase 2 | Completed | Duke University | 209 | 2019-11-04 | 2026-03-19 |
| Sexual Penetration Pain in Postmenopausal Women: A Topical Botanical Drug Treatment 5% sinecatechins ointment, Placebo, 10% sinecatechins ointment - Sexual Pain Disorders, Postmenopausal Symptoms | Phase 2 | Terminated | GTO Pharmaceutical, LLC | 32 | 2018-08-30 | 2022-07-27 |
| Randomized CO2 vs Sham Laser Treatment of Provoked Vestibulodynia Fractional CO2 Laser Treatment, Sham Laser Treatment - Vestibulodynia | Not applicable | Withdrawn | Wake Forest University Health Sciences | 2018-08-01 | 2019-06-10 | |
| Lipofilling as a Treatment for Vestibulodynia Adipose derived stem cell transplantation via lipofilling, Surgical excision - Vestibulodynia | Not applicable | Completed | University Hospital, Ghent | 9 | 2018-04-17 | 2023-07-17 |
| A Study of the Effects of Topical Capsaicin in the Treatment of Provoked Vestibulodynia Capsaicin patch - Vestibulodynia | Phase 2 / Phase 3 | Terminated | Centre Hospitalier Universitaire de Besancon | 10 | 2016-01-20 | 2022-11-14 |
| Study to Compare the Efficacy of Cognitive-behavioral Couple Therapy and Lidocaine for Provoked Vestibulodynia Cognitive Behavioral Couple Therapy, Topical Lidocaine - Vulvodynia, Dyspareunia | Not applicable | Completed | Université de Montréal | 108 | 2014-03-06 | 2019-04-16 |
| Cold Laser: A Modality to Promote Vulvar Healing and Pain Relief Cold laser - Vulvar Vestibulitis, Vestibulodynia | Not applicable | Terminated | ProHealth Care, Inc | 10 | 2014-03-01 | 2017-07-02 |
| Long-Term Assessment of Quality of Life and Effectiveness of Onabotulinumtoxina Injections in Provoked Vestibulodynia Vestibulodynia | Completed | Centre Hospitalier Universitaire de Besancon | 21 | 2013-03-01 | 2016-08-08 | |
| Pilot Study to Assess the Efficacy of Cognitive-behavioral Couple Therapy for Provoked Vestibulodynia Cognitive-behavioral couple therapy - Vestibulodynia | Not applicable | Completed | Université de Montréal | 9 | 2012-05-01 | 2014-12-03 |
| Hormonal Contraceptive Use and the Risk of Provoked Vestibulodynia Hormonal contraceptive - Vestibulodynia | Withdrawn | ahinoam lev sagie | 2012-01-01 | 2015-02-10 | ||
| Efficacy of a Physiotherapy Treatment in Women Suffering From Provoked Vestibulodynia Multimodal physiotherapy, lidocaine - Vestibulodynia | Not applicable | Completed | Université de Sherbrooke | 212 | 2011-10-01 | 2016-11-04 |
| Study of Emu Oil vs. Placebo for Vulvar Pain in Women. Emu Oil, Inert oil - Vulvodynia, Vestibulodynia | Not applicable | Terminated | Corewell Health East | 1 | 2011-02-01 | 2017-01-25 |
| Savella in Treatment for Provoked Vestibulodynia Milnacipran - Vestibulodynia, Vulvodynia | Phase 3 | Completed | University of Tennessee | 31 | 2010-10-01 | 2018-06-11 |
| A Pilot Study of the Effects of Botulinum Toxin in the Treatment of Provoked Vestibulodynia Botulinum Toxin Type A, Saline solution, Indexes - Vestibulodynia | Phase 3 | Completed | Centre Hospitalier Universitaire de Besancon | 60 | 2010-05-04 | 2022-11-10 |
Showing 20 of 22. Sign in to see all of them.
Vulvodynia (22) · Dyspareunia (4) · Vulvar Vestibulitis (4) · Pain (3) · Pelvic Pain (2) · Vulvar Diseases (2) · Agnosia (1) · Back Pain (1) · Chronic Pain (1) · Cystitis, Interstitial (1) · Endometriosis (1) · Fatigue Syndrome, Chronic (1) · Fibromyalgia (1) · Hyperalgesia (1) · Hyperhidrosis (1)
Female Urogenital Diseases (22) · Female Urogenital Diseases and Pregnancy Complications (22) · Genital Diseases (22) · Genital Diseases, Female (22) · Urogenital Diseases (22) · Vulvar Diseases (20) · Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Male Urogenital Diseases (5) · Mental Disorders (5) · Genital Diseases, Male (4) · Vulvitis (4) · Nervous System Diseases (3) · Sexual Dysfunction, Physiological (3)
Lidocaine (2) · Acupuncture Therapy (1) · Botulinum Toxins, Type A (1) · Milnacipran (1) · Nortriptyline (1) · Petrolatum (1) · Saline Solution (1) · Therapeutics (1) · emu Oil (1) · polyphenon E (1)
Centre Hospitalier Universitaire de Besancon (3) · Université de Montréal (2) · Université de Sherbrooke (2) · Corewell Health East (1) · Duke University (1) · GTO Pharmaceutical, LLC (1) · Hadassah Medical Organization (1) · Medstar Health Research Institute (1) · Oslo Metropolitan University (1) · ProHealth Care, Inc (1) · Queen's University (1) · Umeå University (1) · University Hospital, Ghent (1) · University of Tennessee (1) · Vaginal Biome Science (1)
United States (7) · Canada (5) · France (3) · Israel (2) · Belgium (1) · Norway (1) · Sweden (1)
Fabien Pelletier, MD (3) · Sophie Bergeron, PhD (2) · Ahinoam LevSagie, MD (1) · Andrea Nackley, PhD (1) · Candace S Brown, PharmD (1) · Caroline Pukall, PhD (1) · Catherine A Matthews, MD (1) · Cheryl Iglesia, MD (1) · Donna J Carrico, WHNP, MS (1) · Doron Zarfati, MD (1) · Jacob Bornstein, MD (1) · Lila Nachtigall, M.D. (1) · Linda A LaBorde, BS PT (1) · Mary Ojo-Carons, MD (1) · Melanie Morin, Pht, Ph.D. (1)
PMID 25540035, PMID 32434709, PMID 32818475, PMID 36269028, PMID 36862472, PMID 42857927
R01HD096331 (1)