35 completed, 8 unknown, 4 terminated, 3 not yet recruiting. 52 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 52 | Completed 35, Unknown 8, Terminated 4, Not yet recruiting 3, Recruiting 2 |
Follow Vaginitis: new trials by email Literature Review of Vaginitis trials Research Report on Vaginitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV Vaginal estradiol tablets, Vaginal moisturizer - Menopausal Complaints, Vaginal Atrophy | Phase 4 | Not yet recruiting | Albert Einstein College of Medicine | 62 | 2026-09-01 | 2026-07-28 |
| Clinical Study on the Prevention and Treatment of Radiation Vaginitis With Triethanolamine Cream Trolamine (Biafine) - Vaginitis, Radiotherapy Induced Mucositis | Phase 4 | Not yet recruiting | Fujian Cancer Hospital | 238 | 2026-03-01 | 2026-03-25 |
| ASSIST-VLA: Assessment of Symptom-Specific Improvement in Diagnosed Vaginal Atrophy Following Laser Therapy 7-940 - Vaginal Atrophy, Atrophic Vaginitis | Phase 4 | Completed | Stratpharma AG | 11 | 2025-08-13 | 2026-07-20 |
| Probiotics as an Adjunct to Antibiotics for Recurrent Bacterial Vaginosis Probiotic Combination Cap/Tab, Placebo capsules - Recurrent Bacterial Vaginosis | Phase 4 | Completed | Nishtar Medical University | 70 | 2025-08-01 | 2026-10-26 |
| Refining Treatment Options for Trichomonas Vaginalis Infection: A Comparative Analysis of Metronidazole and Secnidazole Metronidazole 500 mg, Secnidazole 2000 MG - Trichomonas Vaginitis, Bacterial Vaginitis | Phase 4 | Recruiting | Tulane University | 1200 | 2025-05-06 | 2026-05-06 |
| Difference in Serum Estrogen Level Based on Methods of Vaginal Estrogen Application (fingertip Vs Applicator Use) in Post-menopausal Women application of the vaginal estrogen cream - Postmenopausal Atrophic Vaginitis, Genitourinary Syndrome of Menopause | Phase 4 | Not yet recruiting | Walter Reed National Military Medical Center | 110 | 2025-02-01 | 2025-02-05 |
| Optimization of Bacterial Vaginosis Treatment in Women of Reproductive Age Longidaza, Metronidazole 500 mg - Bacterial Vaginosis | Phase 4 | Unknown | I.M. Sechenov First Moscow State Medical University | 100 | 2024-06-01 | 2025-04-09 |
| A Pilot Study to Evaluate the Efficacy and Safety of Lactobacillus Species Suppositories on Vaginal Health and pH Lactobacillus Species, Placebo - Bacterial Vaginosis | Phase 4 | Unknown | Vedic Lifesciences Pvt. Ltd. | 75 | 2022-01-03 | 2022-05-02 |
| Comparison of Dequalinium Chloride (Fluomizin) vs Oral Metronidazole for the Treatment of Bacterial Vaginosis Dequalinium Chloride, Metronidazole Oral - Bacterial Vaginosis, Vaginal Infection | Phase 4 | Terminated | Medinova AG | 151 | 2021-07-26 | 2024-10-16 |
| A Randomized Controlled Trial of Treatment of Bacterial Vaginosis Metronidazole, Placebo - Bacterial Vaginoses | Phase 4 | Terminated | Ohio State University | 16 | 2021-04-26 | 2023-06-15 |
| Fluconazol Versus Medical Honey in the Treatment of Recurrent Vulvovaginal Candidiasis Fluconazole, L-Mesitran - Candidiasis, Vulvovaginal, Recurrent Candidiasis of Vagina | Phase 4 | Unknown | Maastricht University Medical Center | 252 | 2021-03-01 | 2020-11-12 |
| Accelerated Genital Tract Aging in HIV: Estradiol Clinical Trial Estradiol Vaginal Insert - HIV Infection, Vaginal Atrophy | Phase 4 | Completed | Kerry Murphy | 60 | 2020-09-01 | 2025-03-14 |
| Study of Lactobacillus in Adjuvant Treatment of RVVC clotrimazole vaginal tablets, Clotrimazole vaginal tablets+ Lactobacillus - Recurrent Vulvovaginal Candidiasis | Phase 4 | Completed | Peking University Shenzhen Hospital | 140 | 2020-07-01 | 2025-06-12 |
| A Prospective, Randomized Controlled Study of the Probiotics as Adjuvant Treatment for Bacterial Vaginosis Metronidazole vaginal suppositories, Metronidazole vaginal suppositories and Probiotics(Umeta-mimi) - Bacterial Vaginosis | Phase 4 | Recruiting | Peking University Shenzhen Hospital | 140 | 2020-02-01 | 2025-06-12 |
| Investigation of Microbiomes of Postmenopausal Women Looking for Outcomes and Response to Estrogen Therapy Conjugated Estrogens Cream - Female Urogenital Diseases, Vaginal Atrophy | Phase 4 | Completed | University of Alabama at Birmingham | 25 | 2019-08-01 | 2024-05-07 |
| Postmenopausal Pessary Users: Estrogen Versus Trimosan Estrogen vaginal cream, Trimo-San vaginal gel - Vaginosis, Vaginosis, Bacterial | Phase 4 | Terminated | The University of Texas Health Science Center, Houston | 4 | 2019-05-07 | 2023-03-08 |
| Evaluation of Efficacy and Safety of Gynomax® XL Ovule Gynomax® XL Vaginal Ovule - Trichomonal Vaginitis, Bacterial Vaginosis | Phase 4 | Completed | Exeltis Turkey | 116 | 2019-04-03 | 2020-01-31 |
| Probiotics as Adjuvant Treatment for Bacterial Vaginosis "Probiotics" and "Metronidazole", Metronidazole Vaginal - Bacterial Vaginosis | Phase 4 | Completed | Peking University Shenzhen Hospital | 126 | 2019-03-26 | 2021-07-09 |
| Use of Vagitories Based on St. John's Wort, Tea Tree Oil and Shepherd's Purse in the Treatment of Vaginal Inflammation Shepherd's Purse extractum oleosum vagitories, Tea tree oil vagitories, Hyperici extractum oleosum vagitories - Non Specific Vaginitis | Phase 4 | Completed | University of Sarajevo | 210 | 2019-03-21 | 2020-09-22 |
| Evaluate the Safety of a Single Oral Dose of Solosec™ (Secnidazole) 2g for the Treatment of Adolescent Girls With BV Secnidazole - Bacterial Vaginoses | Phase 4 | Completed | Lupin Research Inc | 40 | 2018-11-28 | 2020-12-19 |
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Vaginosis, Bacterial (34) · Atrophic Vaginitis (8) · Candidiasis, Vulvovaginal (8) · Candidiasis (3) · Aging, Premature (2) · Dysbiosis (2) · HIV Infections (2) · Infections (2) · Premature Birth (2) · Recurrence (2) · Trichomonas Vaginitis (2) · Vaginal Diseases (2) · Acquired Immunodeficiency Syndrome (1) · Bacterial Infections and Mycoses (1)
Female Urogenital Diseases and Pregnancy Complications (52) · Genital Diseases (52) · Genital Diseases, Female (52) · Female Urogenital Diseases (51) · Urogenital Diseases (51) · Vaginal Diseases (50) · Infections (44) · Bacterial Infections and Mycoses (40) · Bacterial Infections (34) · Mycoses (10) · Vulvar Diseases (8) · Vulvitis (8) · Vulvovaginitis (8) · Candidiasis (7)
Metronidazole (13) · Clindamycin (4) · Clotrimazole (4) · Fluconazole (3) · NuvaRing (3) · Acetylcysteine (2) · Azithromycin (2) · Estradiol (2) · Lacteol (2) · Therapeutics (2) · secnidazole (2) · Anti-Bacterial Agents (1) · Antifungal Agents (1) · Benchmarking (1) · Biafine (1)
Peking University Shenzhen Hospital (6) · University of Alabama at Birmingham (3) · Medinova AG (2) · University of Washington (2) · AGUNCO Obstetrics and Gynecology Centre (1) · Albert Einstein College of Medicine (1) · Assiut University (1) · Christiana Care Health Services (1) · Dongfang Hospital Beijing University of Chinese Medicine (1) · Dr Bharti Daswani (1) · Eastern Virginia Medical School (1) · Exeltis Turkey (1) · Fujian Cancer Hospital (1) · Guangzhou Yipinhong Pharmaceutical CO.,LTD (1) · I.M. Sechenov First Moscow State Medical University (1)
United States (16) · China (9) · India (3) · Egypt (2) · France (2) · Italy (2) · Spain (2) · Bosnia and Herzegovina (1) · Brazil (1) · Czechia (1) · Kenya (1) · Norway (1) · Pakistan (1) · Poland (1) · Russia (1)
Shangrong Fan, M.D. (4) · Jane Schwebke, MD (2) · Kerry J Murphy, MD (2) · Ruifang Wu, M.D. (2) · Ahmed R El-Adawy, Professor (1) · Ahmed Y Shahin, MD (1) · Andrea Lojacono, MD (1) · Bertille de Barbeyrac, MD (1) · Bharti R Daswani, MD, PhD (1) · Christine Johnston, MD, MPH (1) · Deslyn Hobson, M.D. (1) · Fahir Becic, PhD (1) · Gazala Siddiqui, MD (1) · Gilles Brabant, MD (1)
PMID 23985562, PMID 11166145, PMID 12861145, PMID 15028938, PMID 16303068, PMID 16458626, PMID 16647928, PMID 17054136, PMID 18489500, PMID 18698279, PMID 19252451, PMID 21251190, PMID 21854593, PMID 22047020, PMID 22073175, PMID 22143133, PMID 23481118, PMID 23632798, PMID 23935388, PMID 24421044, PMID 25392183, PMID 25415166, PMID 25637520, PMID 25877666, PMID 26220080, PMID 27073145, PMID 30322724, PMID 30762806, PMID 32940765, PMID 3485071, PMID 35550262, PMID 37431855, PMID 37575226, PMID 38336815, PMID 38696172, PMID 39762879, PMID 42031495, PMID 8244360, PMID 8293835, PMID 8628042, PMID 8794418
2019 (1), K23AG062400 (1), R01AG102277 (1), R01AI058033 (1), R01HD077872 (1), U19AI113173 (1)