12 completed, 4 enrolling by invitation, 2 not yet recruiting, 2 terminated. 11 Phase 4, 6 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 5, Enrolling by invitation 2, Terminated 2, Recruiting 1, Unknown 1 |
| Not applicable | 6 | Completed 3, Not yet recruiting 2, Active not recruiting 1 |
Follow Total Shoulder Arthroplasty: new trials by email Literature Review of Total Shoulder Arthroplasty trials Research Report on Total Shoulder Arthroplasty
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Continuous Interscalene Blocks and Rebound Pain Continuous interscalene nerve block, Interscalene Block - Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty | Not applicable | Not yet recruiting | University of Calgary | 154 | 2026-10-01 | 2026-08-19 |
| A Trial to Assess the Safety and Effectiveness of an Anatomic Total Shoulder System Mirror Anatomic Total Shoulder Prosthesis, Medacta Anatomic Shoulder - Shoulder Arthroplasty, Total Shoulder Arthroplasty | Not applicable | Not yet recruiting | Medacta USA | 286 | 2026-09-01 | 2026-09-16 |
| ZYNRELEF vs Continuous Catheter for Pain Management Following Shoulder Arthroplasty Zynrelef, Bupivacaine - Total Shoulder Arthroplasty, Pain Management | Phase 4 | Enrolling by invitation | Washington University School of Medicine | 86 | 2026-02-14 | 2026-02-19 |
| Iodine Drapes Used in TSA Total shoulder arthroplasty, Iodine impregnated drapes, Tissue Culture Samples - Total Shoulder Arthroplasty, Iodine | Phase 4 | Enrolling by invitation | tnicholson | 128 | 2026-01-05 | 2026-07-23 |
| Surgiphor Us in TSA sterile saline solution, Surgiphor, Sample Collection - Total Shoulder Arthroplasty, Shoulder Infection | Phase 4 | Unknown | Rothman Institute Orthopaedics | 126 | 2024-09-16 | 2024-09-19 |
| Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement bupivacaine., Saline - Total Shoulder Arthroplasty | Phase 4 | Recruiting | University of Minnesota | 110 | 2024-08-14 | 2026-03-17 |
| Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients Liposomal bupivacaine, Bupivacaine - Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty | Phase 4 | Terminated | Johnny K. Lee | 78 | 2023-10-23 | 2026-08-06 |
| A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. HTX-011, Bupivacaine Hydrochloride, Ibuprofen - Postoperative Pain, Total Shoulder Arthroplasty | Phase 4 | Completed | Heron Therapeutics | 30 | 2021-10-20 | 2023-10-31 |
| Total Shoulder Arthroplasty Preoperative Pain Threshold and Association With Postoperative Opioid Consumption Pain Threshold using algometer/dolorimeter - Total Shoulder Arthroplasty, Postoperative Pain | Enrolling by invitation | The Cooper Health System | 150 | 2021-05-21 | 2024-08-20 | |
| Ultrasound After Total Shoulder Arthroplasty Ultasound - Total Shoulder Arthroplasty, Rotator Cuff Tears | Completed | Duke University | 12 | 2021-05-20 | 2024-07-22 | |
| Post Surgical Pain in Arthroscopic Shoulder shoulder periarticular injection, suprascapular and axillary nerve block - Total Shoulder Arthroplasty | Not applicable | Completed | Namik Kemal University | 60 | 2021-05-20 | 2021-11-02 |
| Postoperative Pain Control in Total Shoulder Arthroplasty Liposomal bupivacaine, Bupivacaine - Total Shoulder Arthroplasty | Phase 4 | Completed | Scripps Clinic | 100 | 2021-03-01 | 2025-03-21 |
| Subscapularis-Sparing Total Shoulder Arthroplasty Subscapularis-Sparing Total Shoulder Arthroplasty - Total Shoulder Arthroplasty | Enrolling by invitation | University of Utah | 50 | 2021-01-29 | 2026-09-21 | |
| Exparel for Total Shoulder Arthroplasty Exparel, Pain Pump - Total Shoulder Arthroplasty | Phase 4 | Completed | Norton Healthcare | 102 | 2020-08-12 | 2024-11-26 |
| LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs Liposomal Bupivicaine 1.3%, Bupivacaine 0.5% - Post-operative Pain, Total Shoulder Arthroplasty | Phase 4 | Completed | Hartford Hospital | 90 | 2019-03-11 | 2023-09-15 |
| Comparison of Analgesic Efficacy Between of Interscalene Block With Liposomal Bupivacaine With Bupivacaine and Dexamethasone Interscalene catheter, Liposomal bupivacaine, Dexamethasone - Total Shoulder Arthroplasty, Shoulder Osteoarthritis | Completed | Icahn School of Medicine at Mount Sinai | 90 | 2018-08-18 | 2024-05-07 | |
| Posterior Approach to Total Shoulder Arthroplasty posterior approach to total shoulder arthroplasty - Total Shoulder Arthroplasty, Osteo Arthritis Shoulders | Unknown | The Orthopaedic Research & Innovation Foundation | 31 | 2017-10-01 | 2019-05-30 | |
| Pain Management After Total Shoulder Arthroplasty Ropivacaine, liposomal bupivacaine - Glenohumeral Arthritis, Total Shoulder Arthroplasty | Phase 4 | Terminated | The Christ Hospital | 22 | 2016-11-01 | 2017-11-06 |
| Glenosphere Size and Scapular Notch in RSA, Prospective Randomized Study reverse shoulder arthroplasty - Total Shoulder Arthroplasty | Not applicable | Completed | Hospital del Mar | 95 | 2014-09-01 | 2019-03-12 |
| Diagnostic Accuracy of Synovial Biopsy for Implant-Related Shoulder Infections Synovial Biopsy, Open Tissue Biopsy - Total Shoulder Arthroplasty | Not applicable | Active not recruiting | Ottawa Hospital Research Institute | 118 | 2014-06-01 | 2024-04-30 |
Showing 20 of 24. Sign in to see all of them.
Pain, Postoperative (4) · Agnosia (2) · Rotator Cuff Injuries (1)
Neurologic Manifestations (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Pain (4) · Pathologic Processes (4) · Postoperative Complications (4) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Rupture (1) · Shoulder Injuries (1) · Tendon Injuries (1) · Wounds and Injuries (1)
Bupivacaine (6) · Ropivacaine (2) · Acetaminophen (1) · Arthroplasty, Replacement, Shoulder (1) · Dexamethasone (1) · Epinephrine (1) · Ibuprofen (1) · Sodium Chloride (1) · Specimen Handling (1) · bupivacaine-meloxicam drug combination (1)
Hospital for Special Surgery, New York (2) · Duke University (1) · Hartford Hospital (1) · Heron Therapeutics (1) · Hospital del Mar (1) · Icahn School of Medicine at Mount Sinai (1) · Johnny K. Lee (1) · Medacta USA (1) · Namik Kemal University (1) · Norton Healthcare (1) · Ottawa Hospital Research Institute (1) · Rothman Institute Orthopaedics (1) · Scripps Clinic (1) · The Christ Hospital (1) · The Cleveland Clinic (1)
United States (20) · Canada (2) · Turkey (Türkiye) (1)
Jacques T YaDeau, MD, PhD (2) · Alexander Aleem, MD (1) · Catherine J Fedorka, MD (1) · Christopher Klifto, MD (1) · Heinz Hoenecke, MD (1) · Jacob Hutchins, MD, MHA (1) · Johnny K Lee, MD (1) · Joseph P. Iannotti, MD, PhD (1) · Kevin Finkel, MD (1) · Peter Chalmers, M.D. (1) · Peter Lapner, MD (1) · R M Greiwe, MD (1) · Ryan Krupp, MD (1) · Surena Namdari, MD (1)
PMID 21716734, PMID 22067185, PMID 22323951, PMID 23411725, PMID 32858194, PMID 33372953, PMID 36261261