11 completed. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 11 |
Follow Tobacco Dependence: new trials by email Literature Review of Tobacco Dependence trials Research Report on Tobacco Dependence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| C-Raven, a Virtual Tobacco Cessation Intervention in the Community C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker - Tobacco Dependence | Phase 4 | Completed | Johns Hopkins University | 10 | 2024-10-30 | 2026-02-02 |
| Testing C-Raven, a Virtual Tobacco Cessation Intervention, in the Community C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker - Tobacco Dependence | Phase 4 | Completed | Johns Hopkins University | 5 | 2024-04-30 | 2025-09-10 |
| Varenicline OTC Trial on Efficacy and Safety 1.0mg Varenicline b.i.d., 0.5mg Varenicline b.i.d., 0.0mg placebo Varenicline b.i.d. - Tobacco Dependence, Withdrawal Symptoms | Phase 4 | Completed | Arizona State University | 313 | 2018-05-07 | 2024-09-19 |
| UW Quitting Using Intensive Treatment Study (QUITS) Varenicline, Nicotine patch, Placebo Patch - Tobacco Dependence | Phase 4 | Completed | University of Wisconsin, Madison | 1251 | 2017-11-11 | 2023-01-23 |
| Varenicline for Co-occurring Cannabis and Tobacco Use Standard clinical care first, followed by standard clinical care and varenicline, Standard clinical care and varenicline first, followed by standard clinical care - Cannabis Dependence, Tobacco Dependence | Phase 4 | Completed | Albert Einstein College of Medicine | 7 | 2015-01-01 | 2024-09-24 |
| Evaluation of the Safety Profile, Quit and Reduction Rate After Nicorette® Gum and Patch Treatment Nicotine Gum, Nicotine Patch - Tobacco Dependence | Phase 4 | Completed | McNeil AB | 300 | 2009-02-01 | 2012-07-13 |
| The Pharmacogenetic Study , Readiness to Change, and Pharmacological Intervention for Smoking Cessation in Schizophrenia Hihg-doseNRT, Low-dose NRT, bupropion - Tobacco Dependence, Schizophrenia | Phase 4 | Completed | Yu-Li Hospital | 360 | 2006-01-01 | 2010-04-14 |
| Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation sustained-release bupropion (Zyban(R)), Psychodynamic Model Training (R) = PDM(R) - Nicotine Dependence, Substance Abuse | Phase 4 | Completed | Medical University Innsbruck | 779 | 2005-07-01 | 2007-06-11 |
| Smoking Cessation Intervention: Effectiveness in Primary Care nicotine patch, nicotine lozenge, bupropion - Tobacco Dependence | Phase 4 | Completed | University of Wisconsin, Madison | 1346 | 2004-09-01 | 2015-10-14 |
| Bupropion Alone or Combined With Nicotine Gum bupropion + nicotine gum, Active bupropion-Placebo gum, Placebo bupropion-Placebo gum - Tobacco Dependence | Phase 4 | Completed | University of Wisconsin, Madison | 608 | 2001-01-01 | 2016-12-06 |
| Bupropion SR Plus Counseling for Smoking Cessation Active bupropion + counseling, Active bupropion, No counseling, Placebo medication + counseling - Tobacco Dependence, Smoking | Phase 4 | Completed | University of Wisconsin, Madison | 463 | 2001-01-01 | 2016-01-27 |
Tobacco Use Disorder (11) · Smoking Cessation (4) · Marijuana Abuse (1) · Schizophrenia (1) · Smoking (1) · Substance Withdrawal Syndrome (1) · Substance-Related Disorders (1)
Chemically-Induced Disorders (11) · Mental Disorders (11) · Substance-Related Disorders (10) · Behavior (5) · Health Behavior (4) · Schizophrenia Spectrum and Other Psychotic Disorders (1)
Tobacco Use Cessation Devices (5) · Bupropion (3) · Community Health Workers (2) · Nicotine Chewing Gum (2) · Varenicline (2) · Counseling (1) · Nicotine (1) · Nicotine Replacement Therapy (1) · Transdermal Patch (1)
University of Wisconsin, Madison (4) · Johns Hopkins University (2) · Albert Einstein College of Medicine (1) · Arizona State University (1) · McNeil AB (1) · Medical University Innsbruck (1) · Yu-Li Hospital (1)
United States (7) · Austria (1) · China (1) · Taiwan (1)
Timothy B Baker, PhD (2) · Alejandra Ellison-Barnes, MD (1) · Gerald Zernig, M.D. (1) · Jackie Mao (1) · Jeanne Clark, MD (1) · Shadi Nahvi (1) · Thomas C Jackson, MD (1) · Tsuo-Hung Lan, MD, Ph.D (1)
PMID 37230961, PMID 17763111, PMID 18418793, PMID 20008701, PMID 22608375, PMID 34665204
P50DA019706 (2), K23DA025736 (1), P50CA084724 (1), R01DA044125 (1), R01HL109031 (1), R25DA023021 (1), R25GM104547 (1)