12 completed, 8 unknown, 2 suspended, 2 terminated. 6 Phase 2, 6 Phase 4, 4 Not applicable, 4 Phase 3, 2 Phase 1.
Follow Methimazole: new trials by email Literature Review of Methimazole trials Research Report on Methimazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AI-Based Wearable Monitoring (Glandy HYPER) for Antithyroid Drug Dose Adjustment in Graves' Disease Glandy HYPER (AI-based monitoring software), Methimazole - Hyperthyroidism, Graves Disease | Not applicable | Not yet recruiting | THYROSCOPE INC. | 30 | 2026-10-20 | 2026-10-05 |
| Phase 2 Study to Assess Efficacy & Safety of WP1302 Prevent Relapse of MMI w/Draw in Subj. w/ Graves' dz WP1302, WP1302 placebo, methimazole - Graves Disease | Phase 2 | Suspended | Worg Biotherapeutics Inc. | 176 | 2026-03-31 | 2025-05-08 |
| Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' Disease Ergocalciferol 50,000 IU, Methimazole - Graves Disease, Graves' Disease | Phase 2 | Active not recruiting | Northwell Health | 30 | 2025-08-25 | 2026-10-23 |
| Graves' Disease Remission Study: MycoMeth Combo Mycophenolate Mofetil, Oral, 250 Mg, methimazole, oral, 10mg - Graves' Disease | Phase 2 / Phase 3 | Unknown | The First Affiliated Hospital of Xiamen University | 205 | 2023-10-16 | 2024-02-28 |
| A Conservative vs an Ablative Approach for Treatment of Hyperthyroidism in Patients With Graves' Orbitopathy Methimazole, Radioiodine or thyroidectomy - Graves' Orbitopathy | Phase 3 | Unknown | University of Pisa | 52 | 2023-03-02 | 2023-03-17 |
| Methimazole in Patients With Progressive Glioblastoma Methimazole, Recurrent Glioblastoma Surgical Resection, Pharmacodynamic Assays - Glioblastoma, Glioma | Phase 2 | Suspended | Case Comprehensive Cancer Center | 19 | 2023-01-30 | 2026-08-17 |
| Efficacy of Methimazole Dosing Algorithm Methimazole Tablets - Graves Disease | Terminated | Cook County Health | 11 | 2022-02-14 | 2024-12-27 | |
| Inducing a Hypothyroxinemic State in Patients With Recurrent Glioblastoma or Gliosarcoma Liothyronine, Lomustine, Methimazole - Recurrent Glioblastoma, Recurrent Gliosarcoma | Early Phase 1 | Withdrawn | Emory University | 2021-10-20 | 2022-12-02 | |
| Comparative Study of mMASI Before and After Hyperthyroid Therapy in Hyperthyroid Subjects With Melasma Thiamazol - Melasma, Hyperthyroidism | Phase 1 | Completed | Dr.dr.Irma Bernadette, SpKK (K) | 23 | 2019-08-01 | 2020-05-06 |
| Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis Propylthiouracil, Methimazole - Hyperthyroidism, Graves Disease | Phase 3 | Completed | Universitas Indonesia | 36 | 2019-01-01 | 2021-11-12 |
| Effects of Different Treatment Schemes on the Regulation and Recurrence of Graves' Disease Methimazole - Graves Disease, Relapse | Phase 4 | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 240 | 2018-05-01 | 2023-12-11 |
| The Oral Microbiota is Associated With Autoimmune Thyroiditis Methimazole Pill, Propylthiouracil Pill - Microbiota | Unknown | First Affiliated Hospital of Harbin Medical University | 120 | 2017-12-23 | 2018-02-27 | |
| Intestinal Microbiota and Treatment of GD Methimazole Pill, Propylthiouracil Pill - Microbiota | Unknown | First Affiliated Hospital of Harbin Medical University | 90 | 2017-12-23 | 2018-02-14 | |
| Gut Microbiota is Associated With Autoimmune Thyroid Disease Methimazole Pill - Gut Microbiota | Unknown | First Affiliated Hospital of Harbin Medical University | 200 | 2017-04-20 | 2018-01-04 | |
| Total Thyroidectomy Versus Thionamides in Patients With Moderate-to-Severe Graves' Ophthalmopathy Antithyroid Drug, Total thyroidectomy - Graves Disease, Graves Ophthalmopathy | Phase 3 | Unknown | Medical University of Vienna | 60 | 2017-03-01 | 2017-02-28 |
| Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism thionamide treatment for 3 months - Hyperthyroidism | Unknown | Hu Hao | 240 | 2016-07-01 | 2016-07-06 | |
| The Role of Thyroid Status in Regulating Brown Adipose Tissue Activity, White Adipose Tissue Partitioning and Resting Energy Expenditure carbimazole (CMZ) or thiamazole (TMZ) - Hyperthyroidism | Completed | Singapore Institute of Food and Biotechnology Innovation | 30 | 2015-10-13 | 2023-05-25 | |
| Treatment of Graves' Hyperthyroidism With Selenium Plus Methimazole Selenium, Methimazole - Graves' Disease | Not applicable | Completed | University of Pisa | 30 | 2014-01-01 | 2016-04-06 |
| Cardiopulmonary Capacity in Elderly With Different Ranges of Serum Thyroid Stimulating Hormone Methimazole - Healthy | Phase 4 | Unknown | Universidade Federal do Rio de Janeiro | 200 | 2011-09-01 | 2013-05-13 |
| Characteristics of Islet β-cell Functions in Chinese Patients With Graves' Disease Methimazole - Graves Disease | Completed | Weikai Hou | 328 | 2011-06-01 | 2015-03-03 |
Showing 20 of 28. Sign in to see all of them.
Graves Disease (19) · Hyperthyroidism (8) · Graves Ophthalmopathy (4) · Eye Diseases (2) · Glioblastoma (2) · Hashimoto Disease (2) · Recurrence (2) · Atherosclerosis (1) · Autoimmune Diseases (1) · Dermatomyositis (1) · Exophthalmos (1) · Glioma (1) · Gliosarcoma (1) · Insulin Resistance (1) · Melanosis (1)
First Affiliated Hospital of Harbin Medical University (3) · Odense University Hospital (2) · University of Pisa (2) · Case Comprehensive Cancer Center (1) · Cook County Health (1) · Dr.dr.Irma Bernadette, SpKK (K) (1) · Emory University (1) · Hu Hao (1) · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran (1) · Mashhad University of Medical Sciences (1) · Medical University of Vienna (1) · Mikael Lantz (1) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (1) · Northwell Health (1) · Singapore Institute of Food and Biotechnology Innovation (1)
China (6) · United States (5) · Denmark (3) · Indonesia (2) · Italy (2) · Austria (1) · Brazil (1) · Germany (1) · Iran (1) · Mexico (1) · Singapore (1) · Sweden (1)
Yunwei Wei (2) · Cai Ruonan, MD (1) · Claudio Marcocci, MD (1) · Dan Mihailescu, MD (1) · Daniel El-Fassi, MD (1) · David Peereboom, MD (1) · Dylan Lee, MD (1) · Fangsen Xiao, MD (1) · Gao Zhaohua, MD (1) · Guido Dorner, MD (1) · Hu Hao, MD (1) · Irma B Sitohang, MD, PhD (1) · Jan Calissendorff, MD (1) · Jeffrey J. Olson, MD (1)
PMID 19850691, PMID 21175612, PMID 24262987, PMID 26670972, PMID 27272078, PMID 27521067, PMID 27797318, PMID 29396246, PMID 30912336, PMID 32055040, PMID 32616746, PMID 32929476, PMID 34598995, PMID 35223896, PMID 35256693, PMID 35959915, PMID 36346684, PMID 39355401
2015 (2), 2005 (1), P30CA138292 (1)