6 completed, 5 recruiting, 4 unknown, 2 not yet recruiting. 3 Phase 2, 3 Phase 3, 2 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 1, Recruiting 1, Unknown 1 |
| Phase 3 | 3 | Completed 2, Not yet recruiting 1 |
| Not applicable | 2 | Completed 1, Unknown 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Thrombolysis: new trials by email Literature Review of Thrombolysis trials Research Report on Thrombolysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Low-dose ASpirin Use After Intravenous Thrombolysis for Acute Ischemic Cerebral Infarction（ELASTIC） Aspirin (Early, 2h), Aspirin (Standard, 24h) - Cerebral Infarction, Thrombolysis | Phase 4 | Not yet recruiting | Beijing Chao Yang Hospital | 210 | 2026-05-01 | 2026-05-08 |
| Quantitative Net Water Uptake as a Predictor of Functional Outcomes After Intravenous Thrombolysis in Acute Ischemic Stroke International Multicenter Observational Retrospective Study No Interventions - Ischemic Stroke, Thrombolysis | Recruiting | Sigmund Freud PrivatUniversitat | 200 | 2026-02-01 | 2026-07-16 | |
| Thrombolysis in Early Acute Ischemic Stroke Trial-Blood Pressure Management Adjusted BP management group, Usual BP management group - Stroke, Acute Ischemic Stroke | Phase 2 | Recruiting | Shanghai East Hospital | 340 | 2026-01-15 | 2026-01-21 |
| Efficacy and Safety of Intravenous Thrombolysis in Branch Atheromatous Disease Stroke, Thrombolysis | Recruiting | Sigmund Freud PrivatUniversitat | 462 | 2026-01-01 | 2026-07-16 | |
| Tenecteplase vs Medical Management in 4.5-24h LVO no Access to EVT TNK, Standard medical treatment - Acute Ischemic Stroke, Large Vessel Occlusion | Phase 3 | Not yet recruiting | The First Affiliated Hospital of University of Science and Technology of China | 794 | 2025-11-01 | 2025-09-11 |
| Endovascular Treatment With or Without Preceding Intravenous Tenecteplase (TNK) in Patients With Late-window acUte Ischemic Stroke Due to Middle Cerebral Artery Occlusion Tenecteplase, direct EVT - Ischemic Stroke, Acute, Thrombolysis | Phase 3 | Completed | Beijing Tiantan Hospital | 391 | 2024-01-25 | 2025-11-26 |
| A Study to Learn More About How Well BAY3018250 Works and How Safe it is for People With Proximal Deep Vein Thrombosis BAY3018250, Placebo to BAY3018250 - Thrombolysis, Symptomatic Proximal Deep Vein Thrombosis | Phase 2 | Completed | Bayer | 283 | 2024-01-15 | 2026-07-23 |
| Rescue Stenting and Intravenous Thrombolysis In Patients With Large Vessel Ischemic Stroke Large Vessel Occlusion, Stroke Acute | Recruiting | ASST Santi Paolo e Carlo | 400 | 2023-10-21 | 2024-12-17 | |
| Application of Standardized Green Channel Treatment System for Ischemic Stroke in Xi 'an Standardized green channel treatment methods for stroke - Acute Ischemic Stroke, Thrombolysis | Recruiting | Xi'an No.3 Hospital | 3600 | 2022-06-01 | 2024-01-26 | |
| Prospective Study of Cerebrovascular Accidents (CVA) in 3 French Cities (Besançon, Cayenne and Tours) Observational study - Cerebrovascular Accident, Thrombolysis | Completed | Centre Hospitalier de Cayenne | 300 | 2019-05-07 | 2021-06-14 | |
| Contemporary Endovascular Therapies in Treatment of Acute Iliofemoral Deep Vein Thrombosis Contemporary endovascular venous intervention by Zelante pharmacomechanical thrombolysis - Thrombolysis, Deep Vein Thrombosis | Unknown | Guy's and St Thomas' NHS Foundation Trust | 65 | 2019-03-29 | 2019-08-02 | |
| Tenecteplase in Stroke Patients Between 4.5 and 24 Hours Tenecteplase, Placebo - THROMBOLYSIS | Phase 3 | Completed | Genentech, Inc. | 458 | 2019-03-02 | 2024-05-22 |
| CaveoVasc Thrombolysis Protection System, Access Protection Study CaveoVasc® Thrombolysis Protection System - Thrombolysis | Not applicable | Unknown | CaveoMed GmbH | 20 | 2018-01-01 | 2017-12-22 |
| Effect of Ticagrelor and Clopidogrel on Coronary Microcirculation in Patients With Acute Myocardial Infarction Microbubble Contrasted Echocardiography, Platelet Aggregability, Laboratory - Coronary Microvascular Disease, Ticagrelor | Not applicable | Completed | University of Sao Paulo General Hospital | 48 | 2016-10-01 | 2018-05-18 |
| Submassive Pulmonary Embolism Experience With EKOS EkoSonic Endovascular System - Thrombolytic Therapy, Thrombolysis | Unknown | Krishna Mannava, MD, FACS, RPVI | 50 | 2014-02-01 | 2016-10-06 | |
| Hypothermia in Acute Ischemic Stroke - Surface Versus Endovascular Cooling (HAIS-SE) ZOLL Thermogard XP, BARD/Medivance Arctic Sun 5000 - Ischemic Stroke, Thrombolysis | Phase 2 | Unknown | University Hospital Heidelberg | 60 | 2012-08-01 | 2015-02-18 |
| The Impact of a Helicopter Emergency Medical System on Prognosis in Stroke Patients Thrombolysis | Completed | Copenhagen University Hospital, Rigshospitalet | 1068 | 2010-01-01 | 2016-07-11 |
Ischemic Stroke (7) · Stroke (5) · Cerebral Infarction (1) · Hypothermia (1) · Infarction, Middle Cerebral Artery (1) · Microvascular Angina (1) · Pulmonary Embolism (1) · Thrombosis (1) · Venous Thrombosis (1)
Cardiovascular Diseases (13) · Vascular Diseases (13) · Brain Diseases (10) · Central Nervous System Diseases (10) · Cerebrovascular Disorders (10) · Nervous System Diseases (10) · Stroke (5) · Embolism and Thrombosis (3) · Pathological Conditions, Signs and Symptoms (3) · Brain Infarction (2) · Brain Ischemia (2) · Infarction (2) · Ischemia (2) · Necrosis (2) · Pathologic Processes (2)
Tenecteplase (3) · Aspirin (1) · Observation (1)
Sigmund Freud PrivatUniversitat (2) · ASST Santi Paolo e Carlo (1) · Bayer (1) · Beijing Chao Yang Hospital (1) · Beijing Tiantan Hospital (1) · CaveoMed GmbH (1) · Centre Hospitalier de Cayenne (1) · Copenhagen University Hospital, Rigshospitalet (1) · Genentech, Inc. (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Krishna Mannava, MD, FACS, RPVI (1) · Shanghai East Hospital (1) · The First Affiliated Hospital of University of Science and Technology of China (1) · University Hospital Heidelberg (1) · University of Sao Paulo General Hospital (1)
China (5) · Germany (3) · Austria (2) · Canada (2) · Italy (2) · United States (2) · Belgium (1) · Brazil (1) · Bulgaria (1) · Czechia (1) · France (1) · French Guiana (1) · Greece (1) · Hungary (1) · Netherlands (1)
Bertrand De Toffol, PHD (1) · Elena Ballabio, MD (1) · Fengyuan Che, MD (1) · Jacob Steinmetz, MD, PhD (1) · Julian Frederic Hotz, DDr. (1) · Kamilia S. Funder, MD (1) · Krishna Mannava, MD (1) · Lisa K Stevens, MSN (1) · Luca Valvassori, MD (1) · Marek Sykora, Prof. Dr. (1) · Sven Poli, Dr. med. (1) · Ye Tian, Doctor (1) · Yunyun Xiong, MD (1)
PMID 25387730, PMID 26898852, PMID 28231814, PMID 29281734, PMID 30808653, PMID 31662037, PMID 32807436, PMID 33310073, PMID 33793319, PMID 33817340, PMID 35115395, PMID 35218519, PMID 35262424, PMID 35369714, PMID 35598721, PMID 36082254, PMID 38329148, PMID 42099212
2023 (1)