48 completed, 4 unknown, 3 not yet recruiting, 2 terminated. 57 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 57 | Completed 48, Unknown 4, Not yet recruiting 3, Terminated 2 |
Follow Tetanus: new trials by email Literature Review of Tetanus trials Research Report on Tetanus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A First in Human Study Investigating the Safety of an Unloaded and Loaded (With a Tetanus-containing Vaccine Booster) Microneedle Patch in Healthy Adults Microneedle Patch, Tetanus-containing vaccine - Vaccine Delivery, Tetanus | Phase 4 | Not yet recruiting | Microneedle Solutions Ltd | 30 | 2026-08-01 | 2026-06-03 |
| Maternal Immunization With Tetanus Toxoid, Reduced Diphtheria Toxoid, Reduced-dose (2 µg) Recombinant Pertussis Vaccine (TdaP2gen) and Its Effect on the Immune Response in Thai Infants up to 15-18 Months Old Maternal TdaP2gen vaccine, Infant Acellular Pertussis-containing Vaccine, Infant Whole-cell Pertussis-containing Vaccine - Pertussis, Diphtheria | Phase 4 | Not yet recruiting | Chiang Mai University | 320 | 2026-05-26 | 2026-06-02 |
| Study of Concomitant Administration of the sIPV and DTaP or MMR sIPV, DTaP, bOPV 1,3 - Polio, Diphteria, Tetanus and Pertussis | Phase 4 | Not yet recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 2640 | 2025-05-15 | 2025-04-17 |
| PFAS Exposure and Immune Response to Vaccination in Adults TENIVAC - Innate Inflammatory Response, Vaccination | Phase 4 | Completed | Rutgers, The State University of New Jersey | 20 | 2024-11-04 | 2025-12-30 |
| A Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK)'s Infanrix Hexa Vaccine (DTPa-HBV-IPV/Hib) Versus MCM Vaccine BV's Vaxelis Vaccine (DTaP5-HBV-IPV-Hib) in Healthy Infants and Toddlers DTPa-HBV-IPV/Hib, DTaP5-HBV-IPV-Hib, Pneumococcal 13-valent conjugate vaccine - Diphtheria | Phase 4 | Completed | GlaxoSmithKline | 500 | 2021-05-26 | 2024-08-27 |
| Comparing the Incidence of Preeclampsia Between Pregnant Women Receiving Tdap Vaccinations at Week 28 or at Week 36 Tdap Vaccine Administration - Pre-Eclampsia, Diphtheria, Tetanus and Pertussis Vaccine Reaction | Phase 4 | Unknown | Institute of Arthritis Research | 1600 | 2020-12-01 | 2020-06-16 |
| A Phase IV Study to Assess the Safety of EupentaTM Inj Eupenta Inj. - Hepatitis B, Diphtheria | Phase 4 | Unknown | LG Chem | 3000 | 2019-09-23 | 2019-08-14 |
| Evaluation of Immunogenicity and Safety of a Booster Dose of Infanrix Hexa™ in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Infanrix hexa - Diphtheria, Hepatitis B | Phase 4 | Completed | GlaxoSmithKline | 551 | 2016-09-19 | 2020-01-14 |
| Evaluation of Immunogenicity and Safety of the Diphtheria, Tetanus, Pertussis and Inactivated Poliovirus (DPT-IPV) Vaccine Squarekids Co-administered With GSK Biologicals' Human Rotavirus (HRV) Vaccine Rotarix (GSK444563) in Healthy Infants Squarekids, Rotarix - Rotavirus | Phase 4 | Completed | GlaxoSmithKline | 292 | 2016-09-16 | 2019-11-25 |
| Immunogenicity and Safety Study of Infanrix Hexa in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Infanrix hexa, Prevnar13 - Acellular Pertussis, Tetanus | Phase 4 | Completed | GlaxoSmithKline | 601 | 2016-01-22 | 2019-07-09 |
| A Protocol to Collect Human Serum Samples From Healthy Adults for Use as Quality Controls Samples in GlaxoSmithKline (GSK) Biologicals' Assays Menveo®, Boostrix®, Pneumovax 23® - Meningococcal | Phase 4 | Completed | GlaxoSmithKline | 359 | 2014-04-01 | 2017-11-27 |
| Immunogenicity and Safety of a Tetanus-diphtheria Vaccine and a 13-valent Pneumococcal Conjugate Vaccine Tetanus-diphtheria (Td) and PCV13, PCV13 alone, Td alone - Tetanus, Diphtheria | Phase 4 | Completed | Korea University Guro Hospital | 462 | 2013-11-01 | 2018-06-11 |
| Hepatitis B Vaccination in Infants Menjugate, Menitorix, NeisVac-C - Meningococcal Disease, Pneumococcal Disease | Phase 4 | Completed | Public Health England | 300 | 2013-07-01 | 2020-10-01 |
| Tdap Vaccine in Post-Partum Women Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbed onto aluminum phosphate - Diphtheria, Pertussis | Phase 4 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 55 | 2012-10-26 | 2017-05-05 |
| Study of Menactra® in Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of Age Meningococcal polysaccharide diphtheria toxoid conjugate, Meningococcal polysaccharide diphtheria toxoid conjugate + Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate - Meningitis, Meningococcal Infection | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 1394 | 2012-07-01 | 2015-12-15 |
| Immunogenicity of Adacel® and BOOSTRIX® Vaccines in Adolescents Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed (Adacel®), Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed (BOOSTRIX®) - Tetanus, Diphtheria | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 423 | 2012-06-01 | 2016-03-02 |
| Antibody Persistence to REVAXIS or DT Polio and Immune Response to TETRAVAC-ACELLULAIRE Diphtheria, tetanus, polio and pertussis vaccination - Diphtheria, Tetanus | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 278 | 2012-02-01 | 2017-09-11 |
| Safety of PENTAXIM® Given as a Three-Dose Primary Vaccination at 2, 3, and 4 Months of Age in Infants in China DTacP IPV//PRP~T combined vaccine: PENTAXIM® - Diphtheria, Tetanus | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 900 | 2011-12-01 | 2013-03-29 |
| Safety and Immunogenicity in Adults of Revaccination With Adacel® Vaccine 10 Years After a Previous Dose Tetanus Toxoid, Diphtheria Toxoid and Pertussis Vaccine, Tetanus and Diphtheria Toxoids Adsorbed For Adult Use - Tetanus, Diphtheria | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 1330 | 2011-11-01 | 2022-04-28 |
| A Phase 4, Placebo-Controlled, Randomized Study to Evaluate the Immunogenicity and Safety of HPV and Tdap When Administered With MenACWY in Adolescents Placebo + Combined Tetanus, Reduced Diphtheria Toxoid, Acellular Pertussis Vaccine + Quadrivalent Human Papillomavirus Vaccine, MenACWY-CRM Conjugate Vaccine + Combined Tetanus, Reduced Diphtheria Toxoid, Acellular Pertussis Vaccine + Quadrivalent Human Papillomavirus Vaccine - Meningococcal Meningitis | Phase 4 | Completed | Novartis | 801 | 2011-09-01 | 2014-02-14 |
Showing 20 of 57. Sign in to see all of them.
Diphtheria (53) · Whooping Cough (37) · Poliomyelitis (20) · Haemophilus Infections (15) · Hepatitis B (12) · Meningitis (3) · Meningococcal Infections (3) · Pneumococcal Infections (2) · Infant Death (1) · Inflammation (1) · Measles (1) · Meningitis, Meningococcal (1) · Pre-Eclampsia (1) · Trismus (1)
Bacterial Infections (57) · Bacterial Infections and Mycoses (57) · Clostridium Infections (57) · Gram-Positive Bacterial Infections (57) · Infections (57) · Actinomycetales Infections (53) · Corynebacterium Infections (53) · Gram-Negative Bacterial Infections (42) · Bordetella Infections (37) · Respiratory Tract Diseases (37) · Respiratory Tract Infections (37) · Virus Diseases (27) · Nervous System Diseases (24) · Neuroinflammatory Diseases (23) · Central Nervous System Diseases (21)
Tetanus Toxoid (14) · adacel (11) · Boostrix (8) · Diphtheria-Tetanus Vaccine (4) · Meningococcal Vaccines (4) · Pentavac (3) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (3) · 13-valent pneumococcal vaccine (2) · Diphtheria-Tetanus-acellular Pertussis Vaccines (2) · Poliovirus Vaccine, Inactivated (2) · Vaccines (2) · 23-valent pneumococcal capsular polysaccharide vaccine (1) · Blood Specimen Collection (1) · Diphtheria Toxoid (1) · Hepatitis A Vaccines (1)
GlaxoSmithKline (20) · Sanofi Pasteur, a Sanofi Company (13) · Sanofi (6) · Shantha Biotechnics Limited (3) · Bandim Health Project (1) · Chiang Mai University (1) · Crucell Holland BV (1) · Grifols Therapeutics LLC (1) · Institute of Arthritis Research (1) · Institute of Medical Biology, Chinese Academy of Medical Sciences (1) · Korea University Guro Hospital (1) · LG Chem (1) · Microneedle Solutions Ltd (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Norwegian Institute of Public Health (1)
United States (16) · Canada (7) · Italy (5) · Australia (4) · Finland (4) · Germany (4) · Spain (4) · India (3) · Sweden (3) · Thailand (3) · Belgium (2) · China (2) · Czechia (2) · France (2) · Norway (2)
Raman Rao, MD (3) · Craig D Scoville, MD, PhD (1) · Elizabeth Coates, PhD (1) · Eva Netterlid (1) · Kumar Alagappan, MD (1) · Leif Gothefors, Prof. em. (1) · Maria RZ Capeding, MD (1) · Robert Laumbach, MD (1)
PMID 20448468, PMID 20616762, PMID 21134450, PMID 22115634, PMID 23077849, PMID 24176498, PMID 24835247, PMID 25008903, PMID 25230939, PMID 25613716, PMID 25882172, PMID 26057135, PMID 26075317, PMID 29438562, PMID 29573876, PMID 30518331, PMID 31301919, PMID 31377946, PMID 31776027, PMID 31945015, PMID 33612341, PMID 35575974
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