10 recruiting. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Recruiting 10 |
Follow Tauopathies: new trials by email Literature Review of Tauopathies trials Research Report on Tauopathies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation System for Lecanemab Efficacy Using Gold Electrode ECL to Monitor Alzheimer's Biomarkers Lecanemab - Alzheimer Disease | Phase 4 | Recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 100 | 2026-07-10 | 2026-07-07 |
| Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis Acoramidis (AG10) oral tablet - Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM), Amyloidosis | Phase 4 | Recruiting | Eidos Therapeutics, a BridgeBio company | 150 | 2026-07-01 | 2026-07-29 |
| A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE) Zunveyl® - Alzheimer Disease | Phase 4 | Recruiting | Alpha Cognition, Inc | 150 | 2026-05-20 | 2026-10-19 |
| A Study to Evaluate the Effect of Recombinant Zoster Vaccine on New Diagnosis of Dementia in an Older Adult Population Aged 76 Years or Older in Finland Recombinant zoster vaccine, Placebo - Herpes Zoster | Phase 4 | Recruiting | GlaxoSmithKline | 33609 | 2026-03-31 | 2026-05-12 |
| Evaluating the Efficacy and Safety of Lecanemab in Alzheimer's Disease Through Multi-omics Approachs Lecanemab 10 mg/kg, Conventional anti-dementia treatment group - Alzheimer s Disease, Alzheimer Dementia (AD) | Phase 4 | Recruiting | First Affiliated Hospital of Wenzhou Medical University | 200 | 2026-01-01 | 2026-05-22 |
| Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease Daridorexant 50 mg, Placebo, Polysomnography - Alzheimer Disease, Insomnia Disorder | Phase 4 | Recruiting | University Hospital, Montpellier | 62 | 2024-03-13 | 2026-06-25 |
| An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease GV-971, Placebo - Alzheimer's Disease | Phase 4 | Recruiting | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | 1312 | 2023-08-31 | 2023-11-09 |
| Aβ Dynamics in LLMD Escitalopram Oxalate, Placebo - Alzheimer Disease, Major Depressive Disorder | Phase 4 | Recruiting | NYU Langone Health | 60 | 2022-02-04 | 2026-05-06 |
| Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease 18-F-Flortaucipir - Alzheimer Disease | Phase 4 | Recruiting | Mayo Clinic | 614 | 2019-06-27 | 2025-11-24 |
| Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease Gabapentin Enacarbil, Placebo Oral Tablet - Alzheimer Disease | Phase 4 | Recruiting | University of Texas at Austin | 156 | 2017-07-01 | 2022-05-18 |
Alzheimer Disease (10) · Amyloid Neuropathies, Familial (1) · Amyloidosis (1) · Amyloidosis, Hereditary, Transthyretin-Related (1) · Cardiomyopathies (1) · Cognitive Dysfunction (1) · Depressive Disorder, Major (1) · Herpes Zoster (1) · Sleep Initiation and Maintenance Disorders (1)
Brain Diseases (10) · Central Nervous System Diseases (10) · Dementia (10) · Mental Disorders (10) · Nervous System Diseases (10) · Neurocognitive Disorders (10) · Neurodegenerative Diseases (10) · Amyloid Neuropathies (1) · Amyloidosis, Familial (1) · Cardiovascular Diseases (1) · Cognition Disorders (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · DNA Virus Infections (1) · Depressive Disorder (1)
lecanemab (2) · 1-(((alpha-isobutanoyloxyethoxy)carbonyl)aminomethyl)-1-cyclohexaneacetic acid (1) · 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole (1) · 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole (1) · Escitalopram (1) · GV-971 (1) · Gabapentin (1) · Neuropsychological Tests (1) · Tablets (1) · attruby (1) · daridorexant (1)
Alpha Cognition, Inc (1) · Eidos Therapeutics, a BridgeBio company (1) · First Affiliated Hospital of Wenzhou Medical University (1) · GlaxoSmithKline (1) · Green Valley (Shanghai) Pharmaceuticals Co., Ltd. (1) · Mayo Clinic (1) · NYU Langone Health (1) · The Fourth Affiliated Hospital of Zhejiang University School of Medicine (1) · University Hospital, Montpellier (1) · University of Texas at Austin (1)
United States (5) · China (3) · Finland (1) · France (1)
Kathy Richards, PhD (1) · Kejal Kantarci, MD (1) · Nunzio Pomara, MD (1) · Yves Dauvilliers, MD (1)
2025 (1), R01AG051588 (1), R01AG093767 (1), U54AG044170 (1)