29 completed, 8 recruiting, 5 unknown, 4 not yet recruiting. 50 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 50 | Completed 29, Recruiting 8, Unknown 5, Not yet recruiting 4, Terminated 2, Active not recruiting 1, Withdrawn 1 |
Follow Syphilis: new trials by email Literature Review of Syphilis trials Research Report on Syphilis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans Integrated care - Opioid Use Disorder, HIV | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-04-03 | 2026-04-24 |
| Pilot HIV Self-Testing And Self-collected STI Testing Strategy for Sex Worker Empowerment Study Venue-based, peer-enhanced strategy for integrated HIV self-testing (and self-collected STI testing - HIV, Syphilis | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 232 | 2026-11-01 | 2026-10-29 |
| Strengthening, Guidance, Health, Empowerment Self-sampling for six sexually transmitted infections - HIV Infection, Syphilis | Not applicable | Not yet recruiting | University Hospital, Montpellier | 200 | 2026-09-01 | 2026-08-26 |
| Improving Maternal and Child Health Through Point-of-care STI Testing Point-of-care STI tests, Standard of care STI testing - Treponema Pallidum Infection, Chlamydia Trachomatis Infection | Not applicable | Recruiting | Emory University | 756 | 2026-08-11 | 2026-08-19 |
| Ultrasound-Guided Long vs Short Peripheral IV Catheters in Neonates With Congenital Syphilis Receiving Antibiotics Ultrasound-Guided Long Peripheral Intravenous Catheter, Short Peripheral Intravenous Catheter (Conventional Technique) - Infant, Newborn, Syphilis, Congenital | Not applicable | Not yet recruiting | Hospital de Clinicas de Porto Alegre | 104 | 2026-05-01 | 2026-05-11 |
| Doxi-Rio: Study on the Use of Doxycycline to Prevent Sexually Transmitted Infections in Rio de Janeiro Doxycycline - Sexually Transmitted Diseases, Syphilis | Not applicable | Recruiting | Oswaldo Cruz Foundation | 200 | 2025-10-28 | 2026-03-30 |
| Validation of Self Testing Using the INSTI Multiplex HIV1/2 Syphilis Antibody Test INSTI HIV/syphilis Point of Care Self-Test Administration - Hiv, Syphilis | Not applicable | Terminated | Nova Scotia Health Authority | 35 | 2025-10-06 | 2026-10-01 |
| Spotting Syphilis: A Dual Point-of-Care Syphilis Screening Initiative in a Low-Resource Healthcare Setting Chembio HIV/Syphilis rapid POC test - Syphilis, HIV Infections | Not applicable | Completed | The University of Texas Health Science Center, Houston | 153 | 2025-09-30 | 2026-08-28 |
| A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities Chlamydia, gonorrhea, syphilis, and HIV screening - Chlamydia, Gonorrhea | Not applicable | Recruiting | Tulane University | 2322 | 2025-08-14 | 2026-09-21 |
| The Feasibility of Implementing Syphilis Point-of-care Testing Into a Prenatal Clinic for People Facing Barriers to Care Rapid Syphilis/HIV point-of-care test - Syphilis | Not applicable | Recruiting | McMaster University | 77 | 2025-06-25 | 2026-07-07 |
| Offering Routine and Rapid Point of Care (POC) Syphilis Testing in Pregnant Patients Presenting to the Emergency Department Rapid Point of Care (POC) Syphilis testing - Syphilis | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 1500 | 2025-02-04 | 2026-05-06 |
| Ayaangwaamiziwin Initiative: Carefulness and Preparedness INSTI HIV-1/2 Antibody Test, INSTI Multiplex HIV-1/2 Syphilis Antibody Test, Multiplo Complete Syphilis (TP/nTP) Antibody Test - Point-of-Care Testing, HIV | Not applicable | Active not recruiting | Unity Health Toronto | 10000 | 2025-02-01 | 2025-03-25 |
| A Cross-sectional Investigational Study to Evaluate the Sensitivity, Specificity, and Utility of the MedMira Inc. Multiplo® Complete Syphilis (TP/nTP) Antibody Test (POCT) to Diagnose Infectious Syphilis in Participants Attending the Sexual Health Clinic in Ottawa, Ontario. Medical Device - Syphilis, Treponema Pallidum | Not applicable | Recruiting | MedMira Laboratories Inc. | 1300 | 2024-08-26 | 2025-11-18 |
| Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection Screening Motivational interviewing and specimen self-collection - Sexually Transmitted Diseases, Gonorrhea | Not applicable | Completed | University of Michigan | 75 | 2024-04-19 | 2025-07-01 |
| Combination Primary Care and Prevention Services for Women Who Inject Drugs and Exchange Sex in Seattle, Washington Mobile Van Clinic - Opioid Use Disorder, HIV Infections | Not applicable | Completed | University of Washington | 50 | 2024-03-18 | 2026-02-20 |
| The TRIple Elimination Model Of Mother-to-child Transmission Program (TRI-MOM) TRI-MOM intervention - Hiv, Syphilis | Not applicable | Unknown | Institut de Recherche pour le Developpement | 2800 | 2024-03-18 | 2024-06-20 |
| Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis Syphilis Ab Test at the Point- Of-Care Sites iStatis Syphilis Ab Test - Syphilis Infection, Syphilis | Not applicable | Completed | bioLytical Laboratories | 1500 | 2024-03-14 | 2024-08-12 |
| Comparisons of Treatment Responses of Early Syphilis to Benzathine Penicillin G With or Without Doxycycline Benzathine Penicillin G, Doxycycline Capsule - Early Syphilis, Latent, Serological Relapse After Treatment | Not applicable | Recruiting | National Taiwan University Hospital | 688 | 2024-01-01 | 2026-08-06 |
| mLab App Plus: A Randomized Controlled Trial of a Mobile Health (mHealth) Intervention mLab App Plus - HIV Infections, Sexually Transmitted Diseases, Viral | Not applicable | Completed | Columbia University | 40 | 2023-10-17 | 2025-03-05 |
| MENJAGA: Continuous Quality Improvement for Antenatal HIV, Syphilis and Hepatitis B Testing in Indonesia Continuous quality improvement - Hiv, Syphilis | Not applicable | Unknown | Yanri Wijayanti Subronto, MD, PhD, | 2000 | 2023-10-01 | 2023-09-28 |
Showing 20 of 50. Sign in to see all of them.
Chlamydia Infections (14) · Gonorrhea (14) · HIV Infections (10) · Sexually Transmitted Diseases (10) · Acquired Immunodeficiency Syndrome (7) · Hepatitis B (6) · Hepatitis C (6) · Opioid-Related Disorders (3) · Syphilis, Congenital (3) · Coitus (2) · Depression (2) · Homosexuality (2) · Trichomonas Infections (2) · Tuberculosis (2)
Bacterial Infections (50) · Bacterial Infections and Mycoses (50) · Gram-Negative Bacterial Infections (50) · Infections (50) · Spirochaetales Infections (50) · Treponemal Infections (49) · Communicable Diseases (48) · Genital Diseases (48) · Urogenital Diseases (48) · Sexually Transmitted Diseases, Bacterial (47) · Sexually Transmitted Diseases (38) · Blood-Borne Infections (20) · RNA Virus Infections (20) · Virus Diseases (20) · Immune System Diseases (17)
Doxycycline (2) · Penicillin G (2) · Syphilis Serodiagnosis (2) · Ceftriaxone (1) · Centers for Disease Control and Prevention, U.S. (1) · Counseling (1) · Delivery of Health Care, Integrated (1) · Equipment and Supplies (1) · HIV Testing (1) · Mass Screening (1) · Motivational Interviewing (1) · Mouthwashes (1) · Multicenter Studies as Topic (1) · Patient Portals (1) · Spinal Puncture (1)
The University of Texas Health Science Center, Houston (3) · Centers for Disease Control and Prevention (2) · Columbia University (2) · Jacobi Medical Center (2) · MedMira Laboratories Inc. (2) · Unity Health Toronto (2) · University of California, San Diego (2) · University of Washington (2) · California State University, Long Beach (1) · Elizabeth Glaser Pediatric AIDS Foundation (1) · Emory University (1) · Hospital Moinhos de Vento (1) · Hospital de Clinicas de Porto Alegre (1) · Institut de Recherche pour le Developpement (1) · Institute of Tropical Medicine, Belgium (1)
United States (19) · Canada (8) · Mexico (2) · Zambia (2) · Argentina (1) · Belgium (1) · Brazil (1) · Burkina Faso (1) · China (1) · Colombia (1) · Democratic Republic of the Congo (1) · France (1) · Indonesia (1) · Kenya (1) · Kyrgyzstan (1)
Irene Stafford, MD (2) · Akshay Sharma, PhD (1) · Ann N Burchell, PhD (1) · Audun J Lier, MD (1) · Caroline DeSchacht, MD, MSc (1) · Chinazo Cunningham, MD (1) · Chris Kenyon, MD (1) · Christina M Marra, MD (1) · Corina Lelutiu-Weinberger, PhD (1) · Dennis G Fisher, Ph.D. (1) · Despina G. Contopoulos-Ioannidis, MD (1) · Frederick L Altice, MD (1) · Ilesh V Jani, MD, PhD (1)
PMID 21482866, PMID 23107285, PMID 26772390, PMID 26879979, PMID 28495681, PMID 29191814, PMID 29970355, PMID 30107833, PMID 30204761, PMID 30910531, PMID 32444901, PMID 33676596, PMID 34175944, PMID 34193138, PMID 3508756, PMID 35366848, PMID 36557750, PMID 37080628, PMID 37461458, PMID 37658305, PMID 38346403, PMID 38709550, PMID 39208425, PMID 41240948, PMID 41360480, PMID 41361278, PMID 41400951, PMID 41468606, PMID 41649980, PMID 42414214, PMID 42599370
1IK2CX002822-01A1 (1), D43TW009340 (1), K23MH084611 (1), K24NR018621 (1), R01DA029910 (1), R01DA030234 (1), R01HD108201 (1), R01MD020754 (1), R01MH087054 (1), R01MH116829 (1), R01MH118151 (1), R01NS082120 (1), R21AI168606 (1), R34DA054588 (1)