3 completed, 3 not yet recruiting, 2 recruiting, 1 unknown. 3 Not applicable, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 2 | Recruiting 2 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Syphilis, Congenital: new trials by email Literature Review of Syphilis, Congenital trials Research Report on Syphilis, Congenital
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Congenital Syphilis Treatment Trial (CONSISTENT) in Neonates Benzathine Penicillin, Amoxicillin - Syphilis, Congenital | Phase 4 | Not yet recruiting | University of Alabama at Birmingham | 374 | 2026-11-01 | 2026-09-02 |
| Comprehensive Ambulatory Antibiotics for the Treatment of Congenital Syphilis Linezolid (LZD), Amoxicillin, Benzathine Penicillin G - Syphilis, Congenital | Phase 2 | Recruiting | London School of Hygiene and Tropical Medicine | 90 | 2026-05-04 | 2026-10-22 |
| Ultrasound-Guided Long vs Short Peripheral IV Catheters in Neonates With Congenital Syphilis Receiving Antibiotics Ultrasound-Guided Long Peripheral Intravenous Catheter, Short Peripheral Intravenous Catheter (Conventional Technique) - Infant, Newborn, Syphilis, Congenital | Not applicable | Not yet recruiting | Hospital de Clinicas de Porto Alegre | 104 | 2026-05-01 | 2026-05-11 |
| Evaluation of Antimicrobial Prophylaxis to Prevent Syphilis in Pregnancy in Patients at Risk in Rio de Janeiro, Brazil Benzathine penicillin 2.4 million units, Counseling and intensified testing. - Congenital Syphilis | Phase 2 | Recruiting | University of California, Los Angeles | 500 | 2025-09-24 | 2026-06-01 |
| Congenital and Maternal Point of Care Rapid Testing for Syphilis Study, Uganda Syphilis, Syphilis, Congenital | Not yet recruiting | St George's, University of London | 24 | 2025-09-01 | 2025-09-15 | |
| Congenital Syphilis in Switzerland Epidemiological study - Congenital Syphilis | Completed | University Hospital, Geneva | 265 | 2022-10-19 | 2023-08-04 | |
| Point-Of-Care Testing for Congenital Syphilis in Mothers and Newborns Syphilis Health Check POC-test (Diagnostics Direct LLC, NJ) - Maternal Syphilis During Pregnancy - Baby Not Yet Delivered, Congenital Syphilis | Not applicable | Withdrawn | Stanford University | 2019-10-30 | 2019-12-13 | |
| Congenital Syphilis Prospective Cohort With Retrospective Evaluation Syphilis, Congenital | Completed | Hospital de Niños R. Gutierrez de Buenos Aires | 62 | 2019-07-01 | 2022-03-29 | |
| Implementation Strategy of Bio-molecular Techniques for Early Diagnose of Congenital Syphilis and Chagas Diseases Chagas Disease, Syphilis | Unknown | Hospital de Niños R. Gutierrez de Buenos Aires | 560 | 2019-07-01 | 2023-03-01 | |
| Preventing Congenital Syphilis Congenital Syphilis Intervention Group - Congenital Syphilis | Not applicable | Completed | Tulane University School of Public Health and Tropical Medicine | 60386 | 2016-01-11 | 2018-04-26 |
Syphilis (3) · Chagas Disease (1)
Bacterial Infections (10) · Bacterial Infections and Mycoses (10) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (10) · Gram-Negative Bacterial Infections (10) · Infant, Newborn, Diseases (10) · Infections (10) · Spirochaetales Infections (10) · Treponemal Infections (10) · Syphilis (7) · Communicable Diseases (3) · Genital Diseases (3) · Sexually Transmitted Diseases (3) · Sexually Transmitted Diseases, Bacterial (3) · Urogenital Diseases (3) · Euglenozoa Infections (1)
Amoxicillin (2) · Counseling (1) · Epidemiologic Studies (1) · Linezolid (1) · Penicillin G (1) · Penicillin G Benzathine (1)
Hospital de Niños R. Gutierrez de Buenos Aires (2) · Hospital de Clinicas de Porto Alegre (1) · London School of Hygiene and Tropical Medicine (1) · St George's, University of London (1) · Stanford University (1) · Tulane University School of Public Health and Tropical Medicine (1) · University Hospital, Geneva (1) · University of Alabama at Birmingham (1) · University of California, Los Angeles (1)
Argentina (3) · United States (3) · Brazil (1) · Democratic Republic of the Congo (1) · Indonesia (1) · Malawi (1) · South Africa (1) · Switzerland (1) · Uganda (1) · Zambia (1)
Bridget Freyne (1) · David Kimberlin, MD (1) · Despina G. Contopoulos-Ioannidis, MD (1) · Jaime Altcheh, Dr (1) · Jodie Dionne, MD (1) · Michael Marks (1) · Pierre Buekens, MD, PhD (1)
R01AI187414 (1)