10 recruiting. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Recruiting 10 |
Follow Suppuration: new trials by email Literature Review of Suppuration trials Research Report on Suppuration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VATS or Intrapleural Enzymatic Therapy for Patients With Empyema. VATS group, IET - Empyema, Pleural, Pleural Infections | Phase 4 | Recruiting | Amsterdam UMC | 164 | 2026-11-07 | 2026-11-10 |
| A Single Dose of Intravenous Penicillin as an Adjunct to Oral Penicillin in the Treatment of Acute Tonsillitis, Peritonsillar Phlegmon, and Peritonsillar Abscess Benzylpenicillin, Isotonic NaCl (Placebo) - Acute Tonsillitis, Peritonsillar Abscess | Phase 4 | Recruiting | Tejs Ehlers Klug | 154 | 2026-11-01 | 2026-11-04 |
| Clinical Efficacy of Stopping Oral Antibiotics When Symptoms Stop, Compared to 'Finishing the Course' Antibiotics for duration of symptoms, Antibiotics for duration of prescribed course - Urinary Tract Infection, Cellulitis | Phase 4 | Recruiting | Murdoch Childrens Research Institute | 200 | 2026-08-18 | 2026-08-21 |
| Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to Severe Hidradenitis Suppurativa Secukinumab - Hidradenitis Suppurativa (HS) | Phase 4 | Recruiting | Novartis Pharmaceuticals | 36 | 2026-06-01 | 2026-09-09 |
| Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema Fibrinolytic once daily, Fibrinolytic twice daily, DNA degradation once daily - Pleural Infection Bacterial, Pleural Infections | Phase 4 | Recruiting | University of North Carolina, Chapel Hill | 270 | 2025-09-11 | 2026-09-29 |
| Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections Trimethoprim Sulfamethoxazole - Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute | Phase 4 | Recruiting | Indiana University | 100 | 2025-05-20 | 2026-07-29 |
| APPI-Cost Trial for Perforated Appendicitis PVI, Usual Care - Perforated Appendicitis | Phase 4 | Recruiting | The University of Texas Health Science Center, Houston | 346 | 2025-04-07 | 2025-12-11 |
| Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled Trial Clindamycin, Standard of care - Skin Infection, Staphylococcal Infections | Phase 4 | Recruiting | Frieder Schaumburg | 100 | 2024-03-15 | 2024-12-09 |
| Ketamine as a Supplement to Local Anesthesia for Minor Procedures Ketamine, Saline - Pain, Procedural, Minor Laceration | Phase 4 | Recruiting | Loyola University | 108 | 2022-05-25 | 2025-10-03 |
| Partial Oral Antibiotic Treatment for Bacterial Brain Abscess Early transition to oral antibiotics, Standard treatment of intravenous antibiotics - Brain Abscess, Cerebral Abscess | Phase 4 | Recruiting | Henrik Nielsen | 400 | 2020-11-06 | 2025-01-30 |
Cellulitis (2) · Empyema (2) · Empyema, Pleural (2) · Peritonsillar Abscess (2) · Abdominal Abscess (1) · Abscess (1) · Appendicitis (1) · Arthritis, Infectious (1) · Brain Abscess (1) · Hidradenitis Suppurativa (1) · Infections (1) · Inflammation (1) · Lymphadenitis (1) · Mastoiditis (1) · Orbital Cellulitis (1)
Infections (9) · Pathological Conditions, Signs and Symptoms (6) · Pathologic Processes (5) · Respiratory Tract Diseases (5) · Abscess (4) · Inflammation (4) · Respiratory Tract Infections (4) · Skin and Connective Tissue Diseases (4) · Connective Tissue Diseases (3) · Skin Diseases, Infectious (3) · Bacterial Infections (2) · Bacterial Infections and Mycoses (2) · Neurologic Manifestations (2) · Otorhinolaryngologic Diseases (2)
Anti-Bacterial Agents (1) · Clindamycin (1) · Ketamine (1) · Penicillin G (1) · Sodium Chloride (1) · Standard of Care (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1) · secukinumab (1)
Amsterdam UMC (1) · Frieder Schaumburg (1) · Henrik Nielsen (1) · Indiana University (1) · Loyola University (1) · Murdoch Childrens Research Institute (1) · Novartis Pharmaceuticals (1) · Tejs Ehlers Klug (1) · The University of Texas Health Science Center, Houston (1) · University of North Carolina, Chapel Hill (1)
United States (4) · Denmark (2) · Australia (1) · China (1) · Netherlands (1) · Sierra Leone (1)
Dalya Ferguson, MD, MS (1) · Frieder Schaumburg, MD (1) · Jacob Bodilsen, MD (1) · James Wood, MD (1) · Jason Akulian, MD, MPH (1) · Tejs E Klug, MD, DMSc (1) · Trent Reed, DO (1)
K12TR004908 (1)