7 completed. 7 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 7 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Status Epilepticus: new trials by email Literature Review of Status Epilepticus trials Research Report on Status Epilepticus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combined Ketamine and Midazolam for Generalized Convulsive Status Epilepticus Ketamine, Midazolam, Placebo - Generalized Convulsive Status Epilepticus | Phase 2 / Phase 3 | Completed | Sohag University | 144 | 2023-03-21 | 2024-10-29 |
| VIGABatrin in Post-anoxic STATus Epilepticus - Phase IIa Vigabatrin Only Product - Status Epilepticus, Electrographic, Coma | Phase 2 | Completed | University of Florida | 6 | 2021-09-22 | 2024-07-23 |
| Effectiveness of Combined Levetiracetam and Midazolam in Generalized Convulsive Status Epilepticus in Children Levetiracetam, Midazolam, Placebo - Status Epilepticus, Generalized Convulsive Status Epilepticus | Phase 2 | Completed | Sohag University | 144 | 2021-06-20 | 2022-09-21 |
| Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticus IV Ganaxolone active, IV Placebo, non-active - Status Epilepticus, Convulsive Status EPILEPTICUS | Phase 2 | Completed | Marinus Pharmaceuticals | 17 | 2018-02-19 | 2023-03-09 |
| Levetiracetam Versus Sodium Valproate in Children With Refractory Generalized Convulsive Status Epilepticus Intravenous levetiracetam, Sodium valproate - Grand Mal Status Epilepticus | Phase 2 | Completed | Banaras Hindu University | 80 | 2015-01-01 | 2016-09-30 |
| Study to Evaluate SAGE-547 Injection as Adjunctive Therapy for the Treatment of Super-Refractory Status Epilepticus SAGE-547 - Super-refractory Status Epilepticus | Phase 1 / Phase 2 | Completed | Supernus Pharmaceuticals, Inc. | 25 | 2014-03-21 | 2025-09-15 |
| Efficacy and Safety Study Comparing Lorazepam and Diazepam for Children in the Emergency Department With Seizures (Status 2) lorazepam or diazepam - Status Epilepticus | Phase 2 / Phase 3 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 259 | 2008-02-01 | 2012-12-18 |
Coma (1) · Epilepsy (1) · Heart Arrest (1) · Seizures (1)
Nervous System Diseases (7) · Neurologic Manifestations (7) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Seizures (6) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Consciousness Disorders (1) · Heart Diseases (1) · Neurobehavioral Manifestations (1) · Unconsciousness (1)
Midazolam (2) · Diazepam (1) · Ketamine (1) · Levetiracetam (1) · Lorazepam (1) · Valproic Acid (1) · Vigabatrin (1) · brexanolone (1)
Sohag University (2) · Banaras Hindu University (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Marinus Pharmaceuticals (1) · Supernus Pharmaceuticals, Inc. (1) · University of Florida (1)
United States (4) · Egypt (2) · Canada (1)
Abdelrahim A Sadek, MD, PhD (2) · Carolina B Maciel, MD, MSCR (1) · James Chamberlain, MD (1) · Maciej Gasior, MD, PhD (1) · Rajniti Prasad, MD (1) · Robert Lasser, MD, MBA (1)