10 active not recruiting, 6 completed, 6 recruiting, 4 terminated. 9 Not applicable, 9 Phase 2, 6 Phase 1, 1 Early Phase 1, 1 Phase 3.
Follow Stage IIA Lung Cancer AJCC v8: new trials by email Literature Review of Stage IIA Lung Cancer AJCC v8 trials Research Report on Stage IIA Lung Cancer AJCC v8
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilot Trial of E Cigarettes in Pts Diagnosed With Cancer of the Head, Neck, and Lung Best Practice, Nicotine Replacement, Quality-of-Life Assessment - Head and Neck Squamous Cell Carcinoma, Lung Non-Small Cell Carcinoma | Not applicable | Withdrawn | Ohio State University Comprehensive Cancer Center | 2024-01-01 | 2024-04-12 | |
| Quality of Life Intervention to Inform Patient Decision-Making in Early-Stage Lung Cancer Best Practice, Informational Intervention, Questionnaire Administration - Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8 | Not applicable | Recruiting | Roswell Park Cancer Institute | 150 | 2023-12-21 | 2025-10-20 |
| Subcutaneous Atezolizumab for the Treatment of Non-small Cell Lung Cancer Atezolizumab and Recombinant Human Hyaluronidase, Survey Administration - Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 | Phase 2 | Active not recruiting | University of Southern California | 5 | 2022-12-07 | 2026-01-29 |
| Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer Carboplatin, Durvalumab, Paclitaxel - Locally Advanced Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 | Phase 1 | Recruiting | Ohio State University Comprehensive Cancer Center | 28 | 2021-12-06 | 2026-06-30 |
| A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence Quality-of-Life Assessment, Questionnaire Administration, Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine - Chronic Obstructive Pulmonary Disease, Lung Non-Small Cell Carcinoma | Early Phase 1 | Completed | Roswell Park Cancer Institute | 20 | 2021-11-22 | 2026-03-17 |
| Canakinumab for the Prevention of Lung Cancer, the Can-Prevent-Lung Trial Canakinumab, Quality-of-Life Assessment - Lung Carcinoma, Stage I Lung Cancer AJCC v8 | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 50 | 2021-07-20 | 2026-06-12 |
| Cognitive-Behavioral Stress Management Device for the Treatment of Anxiety and Depressive Symptoms in Patients With Stage I-III Breast or Lung Cancer Cognitive Behavior Therapy, Interview, Quality-of-Life Assessment - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8 | Not applicable | Terminated | Jonsson Comprehensive Cancer Center | 5 | 2021-04-08 | 2023-07-25 |
| Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer Best Practice, Biospecimen Collection, Endoscopic Procedure - Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8 | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 800 | 2021-02-21 | 2026-07-15 |
| Sapanisertib and Nivolumab for the Treatment of Stage I-IV Non-small Cell Lung Cancer in Patients Who Have Progressed on Prior PD-1/PD-L1 Inhibitor Therapy, I-OVERCOME Study Nivolumab, Sapanisertib - Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma | Phase 1 / Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2021-02-18 | 2022-05-27 | |
| Adaptive Radiation Planning for the Reduction of Radiation-Induced Toxicity in Patients With Stage II-IV Non-small Cell Lung Cancer Computed Tomography, Contrast Agent - Locally Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma | Not applicable | Active not recruiting | Rutgers, The State University of New Jersey | 34 | 2021-02-11 | 2026-06-11 |
| NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung Cancer Hafnium Oxide-containing Nanoparticles NBTXR3, Radiation Therapy - Recurrent Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8 | Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 34 | 2021-02-10 | 2026-08-19 |
| Sirolimus and Durvalumab for the Treatment of Stage I-IIIA Non-small Cell Lung Cancer Durvalumab, Sirolimus - Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8 | Phase 1 | Terminated | Emory University | 3 | 2021-01-22 | 2024-08-22 |
| Bintrafusp Alfa Before Surgery for the Treatment of Untreated Resectable Non-small Cell Lung Cancer Bintrafusp Alfa, Therapeutic Conventional Surgery - Resectable Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8 | Phase 2 | Terminated | M.D. Anderson Cancer Center | 2 | 2020-08-05 | 2022-07-28 |
| Family Caregivers in Underserved Populations Providing Complex Cancer Care Educational Intervention, Quality-of-Life Assessment, Questionnaire Administration - Malignant Female Reproductive System Neoplasm, Stage 0 Lung Cancer AJCC v8 | Not applicable | Completed | City of Hope Medical Center | 48 | 2020-07-15 | 2024-01-05 |
| Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer Quality-of-Life Assessment, Questionnaire Administration, Survivorship Care Plan - Lung Non-Small Cell Carcinoma, Stage I Colorectal Cancer AJCC v8 | Phase 3 | Active not recruiting | City of Hope Medical Center | 403 | 2020-07-11 | 2026-02-24 |
| Pembrolizumab With or Without Chemotherapy Before Surgery in Treating Patients With Stage I-IIIA Non-Small Cell Lung Cancer Cisplatin, Pembrolizumab, Pemetrexed - Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8 | Phase 2 | Withdrawn | University of California, San Francisco | 2020-05-29 | 2022-03-04 | |
| Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes Biospecimen Collection, Cardiac Event Monitor, Chemoradiotherapy - Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8, Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8 | Completed | Mayo Clinic | 24 | 2019-09-23 | 2026-05-27 | |
| Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung Cancer Ipilimumab, Nivolumab, Radiation Therapy - ALK Gene Rearrangement, EGFR Gene Mutation | Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 21 | 2019-09-13 | 2026-09-14 |
| Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study Computed Tomography with Contrast, Microwave Ablation, Questionnaire Administration - Lung Non-Small Cell Carcinoma, Metastatic Colorectal Carcinoma | Active not recruiting | M.D. Anderson Cancer Center | 74 | 2019-08-07 | 2026-10-07 | |
| Tumor Treating Fields (TTFields) Therapy to Manage Brain Metastases in Small Cell Lung Cancer Questionnaire Administration, Tumor Treating Fields Therapy - Extensive Stage Lung Small Cell Carcinoma, Limited Stage Lung Small Cell Carcinoma | Phase 2 | Terminated | OHSU Knight Cancer Institute | 3 | 2019-06-11 | 2023-10-30 |
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Lung Neoplasms (29) · Carcinoma, Non-Small-Cell Lung (20) · Colorectal Neoplasms (3) · Adenocarcinoma of Lung (1) · Adenocarcinoma, Bronchiolo-Alveolar (1) · Anxiety Disorders (1) · Carcinoma, Neuroendocrine (1) · Colitis (1) · Depression (1) · Esophageal Neoplasms (1) · Liver Neoplasms (1) · Neoplasms (1) · Ovarian Neoplasms (1) · Pneumonia (1) · Pulmonary Disease, Chronic Obstructive (1)
Lung Diseases (29) · Neoplasms by Site (29) · Respiratory Tract Diseases (29) · Respiratory Tract Neoplasms (29) · Thoracic Neoplasms (29) · Neoplasms (28) · Bronchial Neoplasms (20) · Carcinoma, Bronchogenic (20) · Digestive System Diseases (5) · Gastrointestinal Diseases (5) · Colonic Diseases (4) · Digestive System Neoplasms (4) · Gastrointestinal Neoplasms (4) · Intestinal Diseases (4) · Intestinal Neoplasms (3)
Nivolumab (4) · Practice Guidelines as Topic (4) · Radiation (4) · Radiotherapy (4) · Specimen Handling (4) · Standard of Care (4) · Contrast Media (3) · Disulfides (3) · Early Intervention, Educational (3) · Educational Status (3) · Immunoglobulin G (3) · Methods (3) · Pemetrexed (3) · pembrolizumab (3) · 1,2-diaminocyclohexaneplatinum II citrate (2)
M.D. Anderson Cancer Center (11) · City of Hope Medical Center (3) · Roswell Park Cancer Institute (3) · Ohio State University Comprehensive Cancer Center (2) · University of California, San Francisco (2) · Emory University (1) · Jonsson Comprehensive Cancer Center (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · OHSU Knight Cancer Institute (1) · Rutgers, The State University of New Jersey (1) · SWOG Cancer Research Network (1) · University of Southern California (1)
United States (28) · Chile (1) · Colombia (1) · Guam (1) · Mexico (1) · Puerto Rico (1)
Jianjun Zhang (2) · Kathrin Milbury (2) · Anne S Tsao (1) · Anurag K Singh (1) · Arya Amini (1) · Betty Ferrell (1) · Carlos E. Vargas, M.D. (1) · David E Kozono (1) · Ellis Levine, MD (1) · Jennifer W Carlisle, MD (1) · Jeremey Brownstein, MD (1) · Joe Y Chang (1) · Jorge J Nieva, MD (1) · Marcelo V Negrao, MD (1) · Mary Reid, PhD (1)
PMID 33415649, PMID 34036820, PMID 34663123, PMID 35297944, PMID 36040670, PMID 37478883, PMID 38351528, PMID 42830627
P30CA033572 (2), K07CA215546 (1), P30CA014089 (1), P30CA016672 (1), P30CA072720 (1), P30CA138292 (1), P50CA217691 (1), R01CA222382 (1), R01CA249501 (1), R01CA262388 (1), R37CA231522 (1), U10CA031946 (1), U10CA180821 (1), U10CA180830 (1), UG1CA189974 (1)