12 recruiting, 3 completed, 3 unknown, 1 active not recruiting. 12 Not applicable, 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Recruiting 6, Completed 2, Unknown 2, Active not recruiting 1, Terminated 1 |
| Phase 2 | 4 | Recruiting 4 |
| Phase 1 | 1 | Recruiting 1 |
Follow Spine Metastases: new trials by email Literature Review of Spine Metastases trials Research Report on Spine Metastases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease Atorvastatin and Lisinopril, Placebo - Chest Wall Tumor, Breast Cancer | Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 60 | 2026-08-12 | 2026-09-17 |
| Radiofrequency Ablation/Bone Augmentation + Radiotherapy vs Radiotherapy Alone Radiofrequency ablation and bone augmentation with radiotherapy, Radiotherapy alone - Spine Metastases, Bone Pain | Not applicable | Recruiting | University of Minnesota | 36 | 2025-12-01 | 2025-12-03 |
| Spine Oncology Registry Spine Tumor, Spine Metastases | Recruiting | Ohio State University Comprehensive Cancer Center | 3000 | 2025-11-24 | 2026-09-24 | |
| Erector Spinae Plane Block in Spine Surgeries for Postoperative Pain Erector Spinae Plane Block using 0.25 % bupivacaine - Spine Fusion, Spine Metastases | Not applicable | Completed | Ain Shams University | 50 | 2023-12-31 | 2025-05-22 |
| Definitive Radiation for High-Risk Spine Metastases SBRT to the spine - Metastatic Cancer, Metastatic Lung Cancer | Phase 2 | Recruiting | Stony Brook University | 26 | 2023-12-14 | 2025-05-14 |
| Increased Early Pain Relief by Adding Vertebroplasty to SBRT Vertebroplasty, Stereotactic Body Radiation Therapy only - Spine Metastases, Radiation Therapy | Not applicable | Recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 50 | 2023-11-22 | 2026-08-24 |
| Posterior Corpectomy in Thoracolumbar Spinal Metastatsis Posterior corpectomy - Spine Metastases | Unknown | Assiut University | 30 | 2023-11-01 | 2023-11-07 | |
| Effectiveness Of Radiofrequency Ablation And Stabilization In Metastatic Spine Lesions By Positron Emission Computed Tomography (PET-CT) Confirmation Radiofrequency Ablation and Bone Augmentation - Bone Cancer Metastatic, Radiofrequency Ablation | Recruiting | National and Kapodistrian University of Athens | 16 | 2023-01-01 | 2026-04-09 | |
| Prophylactic Radiotherapy of MInimally Symptomatic Spinal Disease Prophylactic Radiotherapy, Standard of care systemic therapy - Spine Metastases | Phase 1 / Phase 2 | Recruiting | Baptist Health South Florida | 74 | 2022-08-29 | 2026-10-13 |
| Post Operative RT for Limited Spine Metastases Spondylectomy, SBRT - Spine Metastases | Not applicable | Recruiting | National Taiwan University Hospital | 111 | 2022-08-01 | 2024-02-06 |
| Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases Stereotactic Laser Ablation, Stereotactic Radiosurgery, MRI guided laser ablation - Neoplasm Metastasis, Spinal Cord Diseases | Not applicable | Recruiting | Henry Ford Health System | 60 | 2021-09-02 | 2026-06-03 |
| Ablation and Cementoplasty for Painful Bone Lesions Ablation and Cementoplasty - Bone Lesion, Bone Metastases | Not applicable | Unknown | University of Calgary | 50 | 2021-06-01 | 2021-04-30 |
| Dose-Escalated Spine SbRT for Localized Metastasis to the Spinal Column Spine stereotactic body radiotherapy - Spine Metastases, Metastasis Spine | Not applicable | Recruiting | Baptist Health South Florida | 60 | 2021-03-14 | 2025-11-14 |
| Radiation Therapy Alone Versus Radiation Therapy Plus Radiofrequency Ablation (RFA)/Vertebral Augmentation Radiation Therapy, Radiofrequency Ablation (RFA) - Oncology, Spine Metastases | Not applicable | Active not recruiting | Baptist Health South Florida | 63 | 2020-05-22 | 2025-02-04 |
| Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases Diagnostic MRI, Planning MRI, Simulation CT - Spine Metastases, Spine Stereotactic Radiosurgery (sSRS) | Phase 2 | Recruiting | Case Comprehensive Cancer Center | 130 | 2020-02-07 | 2026-08-06 |
| Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine MRI with custom MRI spine coil - Thoracic Cancer, Spine Cancer | Not applicable | Completed | Memorial Sloan Kettering Cancer Center | 9 | 2020-01-09 | 2025-07-18 |
| Stereotactic Magnetic Resonance Guided Radiation Therapy MR-guided Linac - Pancreas Cancer, Lung Cancer | Not applicable | Recruiting | Dana-Farber Cancer Institute | 397 | 2019-10-22 | 2025-11-13 |
| Stereotactic Radiotherapy and Image-guided Intensity Modulated Radiotherapy for Spinal Metastatic Tumors Stereotactic radiotherapy, Conventionally-fractionated image- guided Intensity modulated radiotherapy - Radiotherapy, Spine Metastases | Not applicable | Unknown | Peking University Third Hospital | 100 | 2019-06-10 | 2019-07-19 |
| Health Economics Evaluation of Percutaneous Vertebroplasty Compared to Radiation Therapy in Patients With Painful Spine Metastases. External radiotherapy, Percutaneous vertebroplasty - Spine Metastases | Not applicable | Terminated | Centre Leon Berard | 7 | 2015-04-01 | 2017-01-10 |
| Minimally Invasive Surgery (MIS) for Spine Metastases Spine Metastases | Completed | Icahn School of Medicine at Mount Sinai | 14 | 2015-02-01 | 2017-06-20 |
Spinal Cord Neoplasms (4) · Lung Neoplasms (3) · Breast Neoplasms (2) · Neoplasm Metastasis (2) · Thoracic Neoplasms (2) · Agnosia (1) · Bone Neoplasms (1) · Brain Neoplasms (1) · Cardiovascular Diseases (1) · Epidural Neoplasms (1) · Esophageal Neoplasms (1) · Kidney Neoplasms (1) · Mediastinal Neoplasms (1) · Mesothelioma (1) · Neoplasms (1)
Neoplasms (6) · Neoplasms by Site (6) · Central Nervous System Diseases (5) · Central Nervous System Neoplasms (5) · Nervous System Diseases (5) · Nervous System Neoplasms (5) · Pathological Conditions, Signs and Symptoms (4) · Respiratory Tract Diseases (4) · Lung Diseases (3) · Neurologic Manifestations (3) · Pathologic Processes (3) · Respiratory Tract Neoplasms (3) · Signs and Symptoms (3) · Spinal Cord Diseases (3) · Bone Diseases (2)
Radiofrequency Ablation (3) · Vertebroplasty (3) · Radiosurgery (2) · Radiotherapy (2) · Atorvastatin (1) · Bupivacaine (1) · Cementoplasty (1) · Lisinopril (1) · Magnetic Resonance Imaging (1)
Baptist Health South Florida (3) · Ain Shams University (1) · Assiut University (1) · Case Comprehensive Cancer Center (1) · Centre Leon Berard (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Dana-Farber Cancer Institute (1) · Henry Ford Health System (1) · Icahn School of Medicine at Mount Sinai (1) · Memorial Sloan Kettering Cancer Center (1) · National Taiwan University Hospital (1) · National and Kapodistrian University of Athens (1) · Ohio State University Comprehensive Cancer Center (1) · Peking University Third Hospital (1) · Stony Brook University (1)
United States (12) · Canada (2) · China (1) · Egypt (1) · France (1) · Greece (1) · Taiwan (1)
Rupesh Kotecha, MD (2) · Arthur Jenkins, MD (1) · Dongjie He, M Med (1) · Essam Elmorshidy, MD (1) · Fei Xu, M Med (1) · Hongqing Zhuang, M Med (1) · Ian Lee, MD (1) · James B Elder, MD (1) · Jason K Wong (1) · Jianguo Zhang, M Med (1) · Jie Li, M Med (1) · Jonathan Leeman, MD (1) · Junjie Wang, MD (1)