45 completed, 22 recruiting, 13 unknown, 12 terminated. 35 Not applicable, 19 Phase 1, 17 Phase 2, 5 Phase 3, 2 Early Phase 1.
Follow Spinal Cord Neoplasms: new trials by email Literature Review of Spinal Cord Neoplasms trials Research Report on Spinal Cord Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar Spine 3D-printed custom-made non-rigid biomimetic implant - Spinal Tumor | Not applicable | Not yet recruiting | National Taiwan University Hospital | 18 | 2027-01-01 | 2025-12-17 |
| Remimazolam vs Propofol for Motor and Somatosensory Evoked Potentials in Spinal Tumor Surgery Remimazolam, Propofol - Spinal Cord Neoplasms, Spinal Neoplasms | Phase 4 | Not yet recruiting | Beijing Tsinghua Chang Gung Hospital | 190 | 2027-01-01 | 2026-10-28 |
| A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors NEO100 - Pediatric Tumor of CNS, Pediatric Tumor of Brain | Phase 1 | Recruiting | Neonc Technologies, Inc. | 12 | 2026-09-08 | 2026-09-15 |
| Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease Atorvastatin and Lisinopril, Placebo - Chest Wall Tumor, Breast Cancer | Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 60 | 2026-08-12 | 2026-09-17 |
| Postoperative Neurological Recovery and Risk Factor Analysis in Patients With Paralysis Due to Spinal Metastases Metastatic Spinal Tumors, Spinal Cord Compression | Not yet recruiting | Shanghai Changzheng Hospital | 150 | 2026-05-01 | 2026-04-14 | |
| PMCF Study on the Effectiveness and Safety of METROSAN Spinal Systems and BONEGRAFT Filling Materials Titania® Cervical Interbody Fusion Cage (Titanium), Titania® Cervical Interbody Fusion Cage (PEEK), Titania® Posterior Cervical Stabilization System - Degenerative Disc Disease (DDD), Spinal Stenosis | Recruiting | Metrosan End. ve Elk. Mek. Cihazlar ve Tibbi Malz. San. Tic. Ltd. Co. | 561 | 2026-04-27 | 2026-05-29 | |
| Spine Oncology Registry Spine Tumor, Spine Metastases | Recruiting | Ohio State University Comprehensive Cancer Center | 3000 | 2025-11-24 | 2026-09-24 | |
| Liquid Biopsy Following BBB Disruption Using Barrier Disrupting Fields in Patients Undergoing Spine Surgery spinal surgery, BDF - Spinal Tumors | Not applicable | Recruiting | Sheba Medical Center | 20 | 2025-10-16 | 2025-11-04 |
| The Effect of Radiotherapy After Separation Surgery for Spinal Metastases radiotherapy - Spinal Metastases, Spinal Tumor | Not applicable | Recruiting | Wei Xu | 130 | 2025-09-01 | 2026-09-16 |
| Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors Intraspinal Tumor, Juxtamedullary Tumor | Recruiting | University Hospital Muenster | 100 | 2025-05-01 | 2025-07-09 | |
| Study of Olutasidenib and Temozolomide in HGG Olutasidenib + TMZ - High Grade Glioma, Astrocytoma | Phase 2 | Recruiting | Rigel Pharmaceuticals | 60 | 2025-02-01 | 2026-09-01 |
| A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy Abemaciclib, Temozolomide - Glioma | Phase 2 | Active not recruiting | Eli Lilly and Company | 45 | 2024-10-25 | 2026-07-17 |
| Study of Collagen-Based Thrombin Hemostat for the Control of Bleeding in Spinal Surgery CollaStat®, Floseal® - Spinal Tumor, Spinal Injury | Not applicable | Completed | DALIM TISSEN Co., Ltd. | 130 | 2024-10-22 | 2026-01-21 |
| Long-Term Patient Reported Outcomes Following Surgery for Spinal Intradural Tumours Spinal Tumors | Completed | Walton Centre NHS Foundation Trust | 150 | 2024-03-14 | 2026-09-30 | |
| Microsurgical Resection of Intramedullary Spinal Cord Metastases Microsurgical resection of ISCM - Spinal Cord Metastasis, Spinal Cord Tumor Malignant Intramedullary | Unknown | Cantonal Hospital of St. Gallen | 60 | 2023-09-01 | 2024-08-21 | |
| En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor. total en bloc spondylectomy - Spinal Metastases, Spinal Tumor | Recruiting | Shanghai Changzheng Hospital | 182 | 2023-07-01 | 2023-11-13 | |
| Assessment of Quality of Life and Independence, as Well as Received Social Support for Spinal Cancer. BREF,ADL,AIS - Spinal Canal Tumors | Unknown | Andrzej Frycz Modrzewski Krakow University | 100 | 2023-06-15 | 2024-05-02 | |
| RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors RRx-001, Temozolomide, Irinotecan - Brain Tumor, Recurrent, Brain Tumor, Pediatric | Phase 1 | Terminated | EpicentRx, Inc. | 2 | 2023-01-26 | 2024-10-31 |
| MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment Magnetic Resonance Elastography, Assessment and Recording - Spinal Cord Tumors | Not applicable | Recruiting | Shengjing Hospital | 20 | 2023-01-01 | 2026-02-12 |
| Swiss Spinal Tumor Registry (Swiss-STR) Spinal Tumors, Surgical Treatment | Recruiting | Luzerner Kantonsspital | 250 | 2023-01-01 | 2025-03-19 |
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Astrocytoma (26) · Central Nervous System Neoplasms (21) · Medulloblastoma (18) · Brain Neoplasms (16) · Familial ependymoma (16) · Optic Nerve Glioma (16) · Oligodendroglioma (15) · Choroid Plexus Neoplasms (14) · Rhabdoid Tumor (9) · Glioma (8) · Ependymoma (7) · Meningioma (7) · Spinal Stenosis (7) · Burkitt Lymphoma (6)
Central Nervous System Diseases (106) · Neoplasms by Site (106) · Nervous System Neoplasms (106) · Nervous System Diseases (105) · Spinal Cord Diseases (105) · Neoplasms (100) · Central Nervous System Neoplasms (85) · Neoplasms by Histologic Type (41) · Neoplasms, Nerve Tissue (39) · Neoplasms, Glandular and Epithelial (37) · Neuroectodermal Tumors (37) · Neoplasms, Germ Cell and Embryonal (36) · Neoplasms, Neuroepithelial (36) · Glioma (28) · Brain Diseases (27)
Temozolomide (10) · Carboplatin (5) · Radiosurgery (5) · Radiotherapy (5) · Vincristine (4) · Bevacizumab (3) · Etoposide (3) · Magnetic Resonance Imaging (3) · Surveys and Questionnaires (3) · Cisplatin (2) · Disulfides (2) · Fluorodeoxyglucose F18 (2) · Ifosfamide (2) · Immunoglobulin G (2) · Irinotecan (2)
National Cancer Institute (NCI) (11) · Children's Oncology Group (6) · M.D. Anderson Cancer Center (5) · Peking University Third Hospital (4) · City of Hope Medical Center (3) · National Institute of Neurological Disorders and Stroke (NINDS) (3) · Pediatric Brain Tumor Consortium (3) · Beijing Tiantan Hospital (2) · Shanghai Changzheng Hospital (2) · Sohag University (2) · University of Florida (2) · Wake Forest University Health Sciences (2) · Aesculap AG (1) · Andrzej Frycz Modrzewski Krakow University (1) · Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria (1)
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Kevin Camphausen, M.D. (2) · Maryam Fouladi (2) · Maryam Fouladi, MD (2) · Ning Lang (2) · Alberto Broniscer, MD (1) · Amol J. Ghia, MD (1) · Andrew J Shepherd (1) · Anhua Wu, MD (1) · Annamaria Nicolini, RN (1) · Astrid Gnekow (1) · Athos Patsalides (1) · Bart Depreitere, MD, PhD (1) · Bruce H. Cohen, MD (1) · Bryan Oronsky, MD (1)
PMID 14722039, PMID 27488294, PMID 28640703, PMID 29122701, PMID 32556627, PMID 33538338, PMID 11811240, PMID 12942006, PMID 15131446, PMID 17634493, PMID 17705175, PMID 18989154, PMID 20041484, PMID 20694800, PMID 20725730, PMID 21115653, PMID 21339192, PMID 21345842, PMID 21681631, PMID 22000724, PMID 22327407, PMID 23554030, PMID 23709750, PMID 25061868, PMID 25854526, PMID 26335676, PMID 27488296, PMID 27718847, PMID 27752060, PMID 28505327, PMID 28578109, PMID 28649001, PMID 29027863, PMID 29395172, PMID 29777897, PMID 30039254, PMID 30957567, PMID 31049920, PMID 31062234, PMID 31256678, PMID 31501123, PMID 31807602, PMID 32355776, PMID 32554986, PMID 32580249, PMID 33145289, PMID 33293803, PMID 33513968, PMID 33540174, PMID 33550326
U01CA081457 (5), U01CA097452 (4), P30CA012197 (2), U10CA098543 (2), 2005 (1), 2023 (1), P30CA033572 (1), R21CA256421 (1), U10CA081920 (1), U10CA180886 (1)