16 completed. 16 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 16 | Completed 16 |
Follow Spasm: new trials by email Literature Review of Spasm trials Research Report on Spasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Submucosal Dexamethasone for Control of Post-operative Pain, Trismus, and Swelling After Mandibular Third Molar Surgery Dexamethasone, Normal Saline - Impacted Mandibular Third Molar Extraction | Phase 4 | Completed | PAEC General Hospital, Islamabad | 70 | 2024-10-01 | 2025-12-02 |
| Comparison of the Effects of Intraoral Postoperative Dexamethasone Applications After Mandibular Third Molar Surgery In this group, patients received 8 mg IM dexamethasone injection into the masseter muscle after impacted tooth surgery., 8 mg IM dexamethasone injection into the pterygoid cavity after impacted tooth surgery. - Wisdom Teeth, Edema Face | Phase 4 | Completed | Afyonkarahisar Health Sciences University | 20 | 2023-04-28 | 2024-09-20 |
| Lornoxicam Versus Etodolac After Third Molar Surgery Lornoxicam 8 Mg Oral Tablet - Pain, Acute, Edema | Phase 4 | Completed | Kutahya Health Sciences University | 20 | 2022-07-20 | 2023-01-11 |
| Minimizing Pain During Office Intradetrussor Botox Injection Bicarbonate protocol, Standard protocol - Overactive Bladder, Overactive Detrusor | Phase 4 | Completed | Boston Urogynecology Associates | 85 | 2020-08-15 | 2025-03-06 |
| Clinical Efficacy of Diazepam After Whiplash Diazepam Tablets - Whiplash Injuries, Whiplash Injury of Cervical Spine | Phase 4 | Completed | Edin Mešanović | 89 | 2020-01-01 | 2024-12-04 |
| Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema Hyaluronidase Injection mesomedica, Dexamethasone dekort - Edema, Pain | Phase 4 | Completed | Hacettepe University | 60 | 2019-12-01 | 2022-07-20 |
| The Efficacy of A-PRF+ on Postoperative Outcomes Following Surgical Removal of Impacted Mandibular Third Molars (A-PRF+: Advanced Platelet Rich Fibrin) A-PRF+ - PRF | Phase 4 | Completed | University of Medicine and Pharmacy at Ho Chi Minh City | 76 | 2019-10-01 | 2023-04-24 |
| Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery? Dexketoprofen Trometamol, Dexamethasone 21-Phosphate, Therapeutic Elastic Bandage - Third Molar Surgery | Phase 4 | Completed | Tokat Gaziosmanpasa University | 52 | 2019-05-02 | 2019-12-17 |
| Topical Arnica and Mucopolysaccharide Polysulfate on Postoperative Pain, Edema and Trismus : Arnica montana, Mucopolysaccharide polysulfate, Control group - Impacted Third Molar Tooth | Phase 4 | Completed | Abant Izzet Baysal University | 60 | 2018-12-01 | 2020-09-01 |
| Treatments for Fathers With ADHD and Their At-Risk Children (Fathers Too) Vyvanse, Behavioral Parent Training, Methylphenidate - Attention Deficit/Hyperactivity Disorder (ADHD) | Phase 4 | Completed | Seattle Children's Hospital | 19 | 2015-12-01 | 2018-09-12 |
| Pretarsal Versus Preseptal Botulinum Toxin for Patients With Eyelid Spasm Botulinum Toxin Type A 100Unit/Vial (Product), Saline Solution for Injection - Blepharospasm, Hemifacial Spasm | Phase 4 | Completed | The University of Hong Kong | 100 | 2015-07-01 | 2019-04-26 |
| The Effects of ADHD Medication (TEAM) Study OROS-Methylphenidate (MPH) - ADHD | Phase 4 | Completed | Children's Hospital Medical Center, Cincinnati | 204 | 2015-01-12 | 2023-12-21 |
| Imaging Stimulant and Non Stimulant Treatments for ADHD: A Network Based Approach fMRI scans, Atomoxetine arm, Methylphenidate arm - Attention Deficit Hyperactivity Disorder, ADHD | Phase 4 | Completed | Icahn School of Medicine at Mount Sinai | 127 | 2012-10-01 | 2020-07-24 |
| Guanfacine for the Treatment of Hyperactivity in Pervasive Developmental Disorder placebo, extended-release guanfacine - Pervasive Development Disorders | Phase 4 | Completed | Yale University | 62 | 2011-12-01 | 2020-03-31 |
| Levetiracetam in Chronic Neuropathic Pain Following Spinal Cord Injury Levetiracetam - Injuries, Spinal Cord, Pain | Phase 4 | Completed | Danish Pain Research Center | 36 | 2005-11-01 | 2009-08-20 |
| An Effectiveness and Safety Study of Cyclobenzaprine HCl Alone or in Combination With Ibuprofen for Acute Back or Neck Muscle Pain With Muscle Spasm cyclobenzaprine hydrochloride - Pain, Spasm | Phase 4 | Completed | McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. | 1000 | 2011-02-18 |
Trismus (7) · Pain (6) · Edema (5) · Attention Deficit Disorder with Hyperactivity (4) · Pain, Postoperative (2) · Acute Pain (1) · Agnosia (1) · Asperger Syndrome (1) · Autistic Disorder (1) · Blepharospasm (1) · Child Development Disorders, Pervasive (1) · Dystonia (1) · Hemifacial Spasm (1) · Neuralgia (1)
Nervous System Diseases (16) · Neurologic Manifestations (16) · Neuromuscular Manifestations (16) · Pathological Conditions, Signs and Symptoms (16) · Signs and Symptoms (16) · Attention Deficit and Disruptive Behavior Disorders (4) · Mental Disorders (4) · Neurodevelopmental Disorders (4) · Pain (3) · Pathologic Processes (3) · Postoperative Complications (3) · Stomatognathic Diseases (2) · Wounds and Injuries (2) · Autism Spectrum Disorder (1)
Methylphenidate (3) · 5,10-dihydro-5-methylphenazine (2) · Saline Solution (2) · AIEOP acute lymphoblastic leukemia protocol (1) · Arnicae flos extract (1) · Atomoxetine Hydrochloride (1) · Botulinum Toxins, Type A (1) · Control Groups (1) · Dexamethasone (1) · Diazepam (1) · Etodolac (1) · Guanfacine (1) · Injections (1) · Injections, Intramuscular (1) · Levetiracetam (1)
Abant Izzet Baysal University (1) · Afyonkarahisar Health Sciences University (1) · Boston Urogynecology Associates (1) · Children's Hospital Medical Center, Cincinnati (1) · Danish Pain Research Center (1) · Edin Mešanović (1) · Hacettepe University (1) · Icahn School of Medicine at Mount Sinai (1) · Kutahya Health Sciences University (1) · McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. (1) · PAEC General Hospital, Islamabad (1) · Seattle Children's Hospital (1) · The University of Hong Kong (1) · Tokat Gaziosmanpasa University (1) · University of Medicine and Pharmacy at Ho Chi Minh City (1)
Turkey (Türkiye) (5) · United States (5) · Bosnia and Herzegovina (1) · Cyprus (1) · Denmark (1) · Pakistan (1) · Vietnam (1)
Bryan King, MD (1) · Christopher McDougle, MD (1) · Dr Kanza Ateeque, BDS (1) · James Dziura, MPH, PhD (1) · James McCracken, MD (1) · Jeffrey Newcorn, MD (1) · Kurt Schulz, PhD (1) · Lawrence Scahill, MSN, PhD (1) · Marcus M Marcet, MD (1) · Mark A Stein, PhD (1) · Nanna B Finnerup, MD (1) · Nihat Akbulut, Assoc. Dr. (1)
PMID 16197668, PMID 19506571, PMID 21845387, PMID 23512235, PMID 2469747, PMID 25853044, PMID 26910697, PMID 32803439, PMID 32855917, PMID 32950350, PMID 35201607, PMID 37811711, PMID 37913818, PMID 39215323, PMID 40025238, PMID 42816859, PMID 7613277
R01MH083707 (1), R01MH095766 (1)