5 recruiting, 4 unknown, 3 enrolling by invitation, 1 completed. 1 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Somatic Mutation: new trials by email Literature Review of Somatic Mutation trials Research Report on Somatic Mutation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations Blood Sample, Tissue Sample, Excess fluid Sample - Solid Tumor, Solid Tumor, Adult | Withdrawn | University of California, San Francisco | 2026-08-31 | 2026-09-02 | ||
| Development of Polygenic Risk Scores in Colon Cancer Patients Through the Study of Ancestry and Diversity in Genetic Maps of the Brazilian Population - ORIGEM Project Colo-rectal Cancer, Polygenic Risk Score | Enrolling by invitation | D'Or Institute for Research and Education | 500 | 2025-03-14 | 2025-04-08 | |
| SMS 2: Impact of Cancer Therapy on the Somatic Mutational Landscape of Normal Tissues sample collection, Discussing study, Seeking consent - Somatic Mutation, Cancer | Enrolling by invitation | The Wellcome Sanger Institute | 60 | 2024-11-26 | 2025-02-18 | |
| Linking Somatic Mutation Rate With Baseline Exposure in East Palestine Survey, Biological specimen collection, Communications about study updates and future research opportunities - Somatic Mutation | Not applicable | Recruiting | Case Comprehensive Cancer Center | 500 | 2024-08-16 | 2026-03-16 |
| Somatic Mutation in Chronic Liver Disease No intervention - Chronic Liver Disease, Somatic Mutation | Unknown | The Wellcome Sanger Institute | 250 | 2024-07-07 | 2024-10-24 | |
| Somatic Mosaicism in Twins Discordant for Childhood Cancer Biospecimen collection, Questionnaire Administration - Pediatric Central Nervous System Tumor, Central Nervous System Tumor | Recruiting | Children's Oncology Group | 50 | 2024-06-03 | 2026-10-01 | |
| Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study Paraganglioma, Pheochromocytoma | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 400 | 2023-10-01 | 2023-04-07 | |
| MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies Fludarabine, Busulfan, Melphalan - Hematologic Malignancy, Acute Leukemia | Phase 2 | Recruiting | Masonic Cancer Center, University of Minnesota | 70 | 2023-05-11 | 2026-04-06 |
| Molecular Diagnosis of Systemic Autoinflammatory Diseases Inflammatory Disease, Genetic Disease | Recruiting | Institut National de la Santé Et de la Recherche Médicale, France | 300 | 2022-05-18 | 2026-03-05 | |
| Lynch Syndrome Can be Diagnosed Just From Somatic Mismatch Repair Mutation Mismatch repair instability somatic and germline testing - Cancer Gene Mutation, Lynch Syndrome | Unknown | RWJ Barnabas Health at Jersey City Medical Center | 100 | 2019-12-21 | 2020-08-18 | |
| iSITE: Investigation of Somatic Alterations in Tumours of the Eye sample collection, Discussing study/seeking consent, Completion of Study Questionnaire - Somatic Mutation, Ocular Melanoma | Completed | The Wellcome Sanger Institute | 58 | 2019-03-25 | 2026-04-01 | |
| Exploring the Landscape of Somatic Mutations in Human Tissue sample collection - Somatic Mutation | Unknown | The Wellcome Sanger Institute | 1800 | 2019-03-01 | 2024-09-19 | |
| SMS - Study of Somatic Mutations Using Genome Sequencing sample collection, Seeking consent, Sample Collection: Surgical - Somatic Mutation | Enrolling by invitation | The Wellcome Sanger Institute | 600 | 2016-10-01 | 2025-07-20 | |
| A Retrospective Pharmacokinetics and Pharmacogenomics Research of Imatinib in Gastrointestinal Stromal Tumor Treatment Gastrointestinal Stromal Tumors, Germline Mutation | Unknown | Xueding Wang | 200 | 2014-06-01 | 2018-09-13 | |
| A Retrospective Study of EGFR-TKIs,Gefitinib, Erlotinib and Osimertinib in NSCLC Patients Treatment Non-small Cell Lung Cancer (NSCLC), EGFR-TKI Resistant Mutation | Recruiting | Sun Yat-sen University | 1000 | 2012-09-01 | 2023-04-12 |
Anemia, Refractory, with Excess of Blasts (1) · Carcinoma, Non-Small-Cell Lung (1) · Central Nervous System Neoplasms (1) · Chromosome 7, monosomy (1) · Chromosome Aberrations (1) · Colonic Neoplasms (1) · Colorectal Neoplasms, Hereditary Nonpolyposis (1) · Endometrial Neoplasms (1) · Gastrointestinal Stromal Tumors (1) · Genetic Diseases, Inborn (1) · Genetic Predisposition to Disease (1) · Genetic Risk Score (1) · Head and Neck Neoplasms (1) · Hematologic Neoplasms (1) · Influenza, Human (1)
Neoplasms (8) · Neoplasms by Site (7) · Neoplasms by Histologic Type (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Digestive System Diseases (3) · Digestive System Neoplasms (3) · Gastrointestinal Diseases (3) · Gastrointestinal Neoplasms (3) · Neoplasms, Nerve Tissue (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Colonic Diseases (2) · Colorectal Neoplasms (2) · Disease Attributes (2) · Disease Susceptibility (2)
Specimen Handling (4) · Blood Specimen Collection (2) · Busulfan (1) · Cyclophosphamide (1) · Histocompatibility Testing (1) · Levetiracetam (1) · Melphalan (1) · Rituximab (1) · Surveys and Questionnaires (1) · fludarabine (1) · thymoglobulin (1)
The Wellcome Sanger Institute (5) · Case Comprehensive Cancer Center (1) · Children's Oncology Group (1) · Copenhagen University Hospital, Rigshospitalet (1) · D'Or Institute for Research and Education (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Masonic Cancer Center, University of Minnesota (1) · RWJ Barnabas Health at Jersey City Medical Center (1) · Sun Yat-sen University (1) · University of California, San Francisco (1) · Xueding Wang (1)
United Kingdom (5) · United States (4) · China (2) · Brazil (1) · Denmark (1) · France (1)
Min Huang, Professor (2) · Fredrick R Schumacher, PhD (1) · Jenny Poynter, PhD (1) · Margaret MacMillan (1) · Mike Stratton (1) · Peter Campbell (1) · Phil Jones (1) · Phil Jones, PhD (1) · Pui Ying Chan (1) · Ulla Feldt-Rasmussen, Prof., Dr. med. (1) · Varun Monga, MBBS (1)
R21ES036031 (1)