6 completed, 2 terminated, 2 unknown, 1 not yet recruiting. 10 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 5, Unknown 2, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Sleep-Wake Transition Disorders: new trials by email Literature Review of Sleep-Wake Transition Disorders trials Research Report on Sleep-Wake Transition Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of a Daily Magnesium and Melatonin Supplement on Sleep Quality in People With Nighttime Leg Cramps Magnesium and melatonin based multi-ingredient dietary supplementation, Placebo - Poor Sleep Quality, Leg Cramps, Nocturnal | Not applicable | Recruiting | StudySetGo | 50 | 2026-10-10 | 2026-10-26 |
| Weighted Blanket in Pregnancy Weighted Blanket - Leg Cramps, Nocturnal, Poor Sleep Quality | Not applicable | Not yet recruiting | Ataturk University | 50 | 2025-12-30 | 2025-12-30 |
| Effect of Vitamin K2 in the Treatment of Nocturnal Leg Cramps in Older Population Vitamin K2, Placebo - Nocturnal Leg Cramps | Not applicable | Completed | The Third People's Hospital of Chengdu | 200 | 2022-10-01 | 2025-01-17 |
| Exercise and Dry Needling Treatment Combination in Nocturnal Calf Cramps Stretching exercise, Dry needling - Nocturnal Leg Cramps, Myofascial Pain Syndrome | Not applicable | Unknown | Kars State Hospital | 50 | 2020-12-01 | 2021-06-10 |
| Extracorporeal Shock Wave Therapy Treatment for Nocturnal Leg Cramps Extracorporeal shock wave therapy, General physical therapy - Nocturnal Leg Cramps | Not applicable | Unknown | China Medical University Hospital | 30 | 2019-03-05 | 2019-03-11 |
| The Study of Efficacy and Safety of a 60-day Use of the Magnox Comfort Compared to the Placebo in Subjects With NLC Magnox Comfort, Placebo - Nocturnal Leg Cramps | Not applicable | Completed | Naveh Pharma LTD | 216 | 2018-02-09 | 2019-01-16 |
| Effect of Theraworx/[pH]Uel on Night-time Leg Cramps and Spasm Symptoms Theraworx, Placebo - Leg Cramp, Nocturnal | Not applicable | Completed | Sport and Spine Rehab Clinical Research Foundation | 57 | 2016-11-01 | 2019-03-25 |
| Nocturnal Leg Cramps in Geneva : an Observational Study observational study, no intervention - Sleep Wake Transition Disorders, Nocturnal Leg Cramps | Completed | University of Geneva, Switzerland | 129 | 2015-03-01 | 2018-05-22 | |
| Magnesium Oxide Monohydrate for Nocturnal Leg Cramps MAGNOX 520®, placebo - Nocturnal Leg Cramps, Quality of Life | Phase 4 | Terminated | Uzi Milman | 94 | 2013-02-01 | 2017-07-21 |
| The Effects of the Myofascial Trigger Point Injections on Pain and Sleep Disturbance in Patients With Nocturnal Leg Cramps With Trigger Points on Gastrocnemius Muscle Myofascial trigger point injections on gastrocnemius muscle - Nocturnal Leg Cramps | Not applicable | Completed | Yonsei University | 13 | 2012-06-01 | 2015-01-28 |
| Vitamin D for Painful Nocturnal Leg Cramps vitamin d, placebo - Leg Cramps, Nocturnal | Not applicable | Terminated | University of Wisconsin, Madison | 29 | 2007-08-01 | 2019-09-17 |
| Exploring the Role of Magnesium in Rest Cramps Intravenous Infusion of Magnesium Sulfate - Rest Cramps | Not applicable | Completed | University of British Columbia | 54 | 2007-01-01 | 2008-12-10 |
Muscle Cramp (3) · Anxiety Disorders (1) · Magnesium Deficiency (1) · Myofascial Pain Syndromes (1) · Parasomnias (1) · Sleep Initiation and Maintenance Disorders (1) · Spasm (1) · Vitamin D Deficiency (1)
Mental Disorders (12) · Nervous System Diseases (12) · Sleep Wake Disorders (12) · Parasomnias (11) · Muscular Diseases (4) · Musculoskeletal Diseases (4) · Neurologic Manifestations (4) · Neuromuscular Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Deficiency Diseases (2) · Malnutrition (2) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2) · Avitaminosis (1)
Dry Needling (1) · Ergocalciferols (1) · Extracorporeal Shockwave Therapy (1) · Lactose (1) · Magnesium (1) · Muscle Stretching Exercises (1) · Observation (1) · Vitamin D (1) · Vitamin K 2 (1)
Ataturk University (1) · China Medical University Hospital (1) · Kars State Hospital (1) · Naveh Pharma LTD (1) · Sport and Spine Rehab Clinical Research Foundation (1) · StudySetGo (1) · The Third People's Hospital of Chengdu (1) · University of British Columbia (1) · University of Geneva, Switzerland (1) · University of Wisconsin, Madison (1) · Uzi Milman (1) · Yonsei University (1)
United States (3) · Turkey (Türkiye) (2) · Canada (1) · China (1) · Israel (1) · South Korea (1) · Switzerland (1) · Taiwan (1) · Ukraine (1)
Fatih Bagcier, M.D. (1) · Garrison Scott, MD (1) · Hubert Maisonneuve, MD (1) · Mary E Elliott, PhD (1) · Nitsan Primor (1) · Noga Maor Rougin, MD (1) · Uzi Milman, MD (1)
PMID 28241153, PMID 33275278, PMID 33998664, PMID 34719399, PMID 36908924, PMID 39466236