79 completed, 29 unknown, 15 recruiting, 8 not yet recruiting. 71 Not applicable, 18 Phase 2, 7 Phase 1, 6 Phase 3, 3 Early Phase 1.
Follow Milk Hypersensitivity: new trials by email Literature Review of Milk Hypersensitivity trials Research Report on Milk Hypersensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GOAt Milk Formula-based Ladder Versus Cow's Milk Ladder oral food challenge (OFC) - Food Allergy, Cow's Milk Protein Allergy | Not applicable | Not yet recruiting | Medical University of Warsaw | 92 | 2027-01-02 | 2026-08-31 |
| Performance of the Basophil Activation Test in the Diagnosis of IgE-mediated Cow's Milk Allergy in Infants and Evaluation of Hydrolysate Allergenicity. Basophil activation test, quality of life questionnaire - Milk Allergy | Not applicable | Not yet recruiting | Odense University Hospital | 100 | 2027-01-01 | 2026-10-28 |
| TeriFort 1+ Study: Efficacy and Safety of an Extensively Hydrolyzed Formula in the Management of Cow's Milk Protein Allergy in Young Children: A Prospective, Single-Arm Interventional Study (TeriFort 1+) Diagnosed with or highly suspected CMPA: Extensively Hydrolyzed Formula intervention - Cow's Milk Protein Allergy (CMPA) | Not applicable | Not yet recruiting | Shanghai Teyi Yinuo Health Technology Co., Ltd. | 50 | 2026-11-01 | 2026-10-02 |
| Oral Immunotherapy for Children With Cow's Milk Allergy Oral immunotherapy with cow's milk - Milk Allergy, Cow's, Food Allergy in Children | Not applicable | Not yet recruiting | Laura Ozer Kettner | 56 | 2026-09-01 | 2026-08-17 |
| Dietary Restriction Efficiency Assessment in CMPA Amino Acid Formula (AAF), Extensively Hydrolyzed Formula (eHF) - Cow's Milk Protein Allergy | Not applicable | Not yet recruiting | Ruijin Hospital | 360 | 2026-09-01 | 2026-08-18 |
| A 52-week Study of Remibrutinib in IgE-mediated Food Allergy Remibrutinib, Placebo - IgE-Mediated Food Allergy, Peanut Allergy | Phase 3 | Recruiting | Novartis Pharmaceuticals | 576 | 2026-08-27 | 2026-10-13 |
| A Phase 1 Study of Cizutamig in IgE Mediated Diseases Cizutamig - IgE-Mediated Hypersensitivity, IgE Mediated Food Allergy | Phase 1 | Withdrawn | Candid Therapeutics | 2026-04-01 | 2026-07-22 | |
| Safety and Efficacy Evaluation of an Extensively Hydrolyzed Formula in Infants With Cow's Milk Protein Allergy (CMPA) Feihe Extensively Hydrolyzed Formula, Nestlé Extensively Hydrolyzed Formula - Cow's Milk Protein Allergy (CMPA) | Not applicable | Not yet recruiting | Heilongjiang Feihe Dairy Co. Ltd. | 124 | 2026-03-05 | 2026-03-19 |
| Evaluation of the Tolerance of a New Formula Based on Hydrolyzed Rice Proteins in Children With Cow's Milk Allergy Rice formula (New formula based on hydrolysed rice proteins), Placebo formula - IgE-Mediated Cow Milk Allergy | Not applicable | Recruiting | Health and Happiness Research Limited | 29 | 2026-01-23 | 2026-11-04 |
| A Long Term, Observational Follow-Up Study of Children and Young People Who Underwent an 18-Month Course of Oral Immunotherapy Treatment for Peanut, Egg or Milk Allergy (5-15 Years Post-Treatment) Food Allergies, Peanut Allergies | Recruiting | Murdoch Childrens Research Institute | 147 | 2026-01-13 | 2026-02-02 | |
| Pasteurised Donor Human Milk Supplementation for Term Babies Standard care Cow's milk based formula, Dietary Supplement: PDHM Pasteurised Donor Human Milk - Neonatal Hypoglycemia, Metabolic Complication | Phase 4 | Recruiting | The University of Queensland | 1444 | 2025-12-04 | 2026-09-02 |
| Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy RPT904, Placebo - Ig-E Mediated Food Allergy | Phase 2 | Recruiting | RAPT Therapeutics, Inc., a member of the GSK plc group of companies | 100 | 2025-10-22 | 2026-07-28 |
| Goat vs. Cow Milk Digestive Tolerance Cow milk, Goat Milk - Milk Intolerance, Milk Hypersensitivity | Not applicable | Recruiting | Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement | 20 | 2025-09-25 | 2025-11-20 |
| Validation Of A Parent Administered Symptom Score For Unsettled Infants (Every Baby is UnIQue) Online parent administered questionnaire - Colic, Infantile, Milk Allergy, Cow's | Not yet recruiting | University Hospital Southampton NHS Foundation Trust | 350 | 2025-09-01 | 2025-08-13 | |
| Early Supplementation for Cow's Milk Allergy Prevention Cow's milk formula [CMF], Amino-acid formula [AAF], Donor human milk [DHM] - Food Allergy, Cow's Milk Allergy | Not applicable | Not yet recruiting | Medical University of Warsaw | 1000 | 2025-07-01 | 2025-07-17 |
| Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study "Rush" regimen, "Conventional" regimen - Food Allergy in Children, Milk Allergy | Phase 2 / Phase 3 | Recruiting | Pablo Rodríguez del Rio | 40 | 2025-06-03 | 2026-02-18 |
| Post-failure Stepwise Heat-Denaturated Protein Introduction for Tolerance Induction in Cow's Milk Allergy Observational Cohort Study Cow's Milk Protein Allergy | Recruiting | Universitaire Ziekenhuizen KU Leuven | 30 | 2025-03-31 | 2026-03-04 | |
| SMASH: Study to Evaluate the Clinical Efficacy of an Extensively Hydrolysed Infant Formula With Synbiotics and a Human Milk Oligosaccharide (HMO) in Infants With Cow's Milk Protein Allergy (CMPA) Cow's Milk Protein Allergy (CMPA), Food Hypersensitivity | Recruiting | Outcomes'10 | 41 | 2025-02-07 | 2026-01-15 | |
| Effectiveness and Safety of Milk Ladders in Children with IgE-Mediated Cow's Milk Protein Allergy oral food challenge (OFC) - Cow Milk Allergy, Food Allergy | Not applicable | Recruiting | Medical University of Warsaw | 92 | 2024-12-03 | 2025-03-18 |
| Hypoallergenicity of a Hydrolyzed Rice Protein-based Formula in Infants and Young Children With Cow's Milk Protein Allergy Experimental formula, Control formula - Cow's Milk Protein Allergy | Not applicable | Completed | Société des Produits Nestlé (SPN) | 43 | 2024-11-05 | 2026-05-08 |
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Food Hypersensitivity (43) · Egg Hypersensitivity (17) · Hypersensitivity (11) · Peanut Hypersensitivity (10) · Nut Hypersensitivity (7) · Dermatitis, Atopic (4) · Wheat Hypersensitivity (4) · Anaphylaxis (3) · Breast Feeding (3) · Hypersensitivity, Immediate (3) · Immune System Diseases (3) · Disease (2) · Eosinophilic Esophagitis (2) · Lactose Intolerance (2)
Hypersensitivity, Immediate (142) · Immune System Diseases (142) · Hypersensitivity (134) · Food Hypersensitivity (102) · Nut and Peanut Hypersensitivity (14) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (9) · Digestive System Diseases (8) · Pathological Conditions, Signs and Symptoms (8) · Gastrointestinal Diseases (7) · Genetic Diseases, Inborn (7) · Intestinal Diseases (5) · Nutritional and Metabolic Diseases (5) · Pathologic Processes (5) · Behavior (4) · Dermatitis (4)
Milk (9) · Basophil Degranulation Test (3) · Immunotherapy (3) · Blood Specimen Collection (2) · Defecation (2) · Infant Formula (2) · Omalizumab (2) · Surveys and Questionnaires (2) · 2-Acetylaminofluorene (1) · Aging (1) · Blood Cell Count (1) · CMF regimen (1) · Cultured Milk Products (1) · Desensitization, Psychologic (1) · Dietary Supplements (1)
Federico II University (18) · Société des Produits Nestlé (SPN) (9) · United Pharmaceuticals (6) · Assiut University (4) · National Institute of Allergy and Infectious Diseases (NIAID) (4) · Nutricia UK Ltd (4) · Ain Shams University (3) · Johns Hopkins University (3) · Medical University of Warsaw (3) · Abbott Nutrition (2) · Alladapt Immunotherapeutics, Inc. (2) · Children's Hospital of Philadelphia (2) · DBV Technologies (2) · King's College London (2) · Laboratorios Ordesa (2)
United States (32) · Italy (29) · France (12) · United Kingdom (12) · Spain (9) · Belgium (8) · Egypt (7) · Australia (6) · Poland (6) · Canada (5) · Israel (5) · China (4) · Turkey (Türkiye) (3) · Finland (2) · Netherlands (2)
Anna Nowak-Wegrzyn, MD (6) · Hugh A. Sampson, MD (3) · Antonella Cianferoni, MD, PhD (2) · Jasmine Leus, MD (2) · Kate Sauer, MD (2) · Katrien Coppens, MD (2) · Mei-Lun Wang, MD (2) · Robert Wood, MD (2) · Scott Sicherer, MD (2) · Sophie Verelst, MD (2) · Adriana Chebar Lozinsky Rolnik (1) · Ahmed Saber (1) · Alexandra Santos, MD PhD (1)
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