Sickle Cell Anemia: Clinical Trials

15 trials for Sickle Cell Anemia, newest first

ClinicalTrials Daily · Areas · Conditions · Drugs · Sponsors ·

8 completed, 5 terminated, 1 enrolling by invitation, 1 recruiting. 15 Phase 3.

By phase and status

Phase	Trials	Status
Phase 3	15	Completed 8, Terminated 5, Enrolling by invitation 1, Recruiting 1

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Trials (filtered) newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease CTX001 - Beta-Thalassemia, Thalassemia	Phase 3	Recruiting	Vertex Pharmaceuticals Incorporated	26	2022-08-02	2026-03-23
A Long-term Follow-up Study in Participants Who Received CTX001 CTX001 - Beta-Thalassemia, Thalassemia	Phase 3	Enrolling by invitation	Vertex Pharmaceuticals Incorporated	160	2021-01-20	2026-08-11
Hydroxyurea Optimization Through Precision Study Hydroxyurea - Sickle Cell Disease, Sickle Cell Anemia	Phase 3	Completed	Lifespan	104	2019-01-17	2025-06-18
Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas Hydroxyurea - Sickle Cell Anemia, Sickle Cell Disease	Phase 3	Completed	Indiana University	187	2017-07-26	2020-02-20
Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa Moderate Dose Hydroxyurea, Low Dose Hydroxyurea - Sickle Cell Disease, Sickle Cell Anemia	Phase 3	Completed	Vanderbilt University Medical Center	120	2017-01-01	2022-01-19
Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease Rivipansel - Sickle Cell Anemia, Sickle Cell Disease	Phase 3	Terminated	GlycoMimetics Incorporated	154	2015-12-16	2021-02-10
Novel Use Of Hydroxyurea in an African Region With Malaria Hydroxyurea, Placebo - Sickle Cell Anemia, Sickle Cell Disease	Phase 3	Completed	Indiana University	208	2014-09-01	2018-12-04
Sparing Conversion to Abnormal TCD (Transcranial Doppler) Elevation (SCATE) Hydroxyurea - Sickle Cell Anemia	Phase 3	Terminated	Children's Hospital Medical Center, Cincinnati	38	2012-05-01	2016-02-08
Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea Hydroxyurea - Sickle Cell Anemia	Phase 3	Terminated	Children's Hospital Medical Center, Cincinnati	159	2011-08-01	2020-07-22
A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia L-glutamine, Placebo - Sickle Cell Anemia, Sickle ß0-Thalassemia	Phase 3	Completed	Emmaus Medical, Inc.	230	2010-05-01	2020-08-19
Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia sulfadoxine pyrimethamine - Sickle Cell Anemia, Malaria	Phase 3	Completed	Makerere University	220	2006-10-01	2009-07-02
A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study Bosentan - Pulmonary Hypertension, Sickle Cell Anemia	Phase 3	Terminated	Actelion	236	2006-03-01	2025-02-03
A Study Evaluating the Long-Term Safety of ICA-17043 in Sickle Cell Disease Patients With or Without Hydroxyurea Therapy ICA-17043 - Sickle Cell Disease, Sickle Cell Anemia	Phase 3	Terminated	Icagen	51	2006-02-01	2007-09-11
Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial transfusion therapy - Sickle Cell Anemia, Stroke	Phase 3	Completed	Washington University School of Medicine	196	2004-12-01	2016-02-08
Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease poloxamer 188 - Sickle Cell Anemia	Phase 3	Completed	Mast Therapeutics, Inc.	300	1997-11-01	2012-03-06

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