8 recruiting. 8 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Recruiting 8 |
| Phase 2 | 1 | Recruiting 1 |
Follow Septic Shock: new trials by email Literature Review of Septic Shock trials Research Report on Septic Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial of Adjunctive Fludrocortisone (50mcg, 100mcg or Placebo) in Critically Ill Patients With Septic Shock Receiving Hydrocortisone, Evaluating Survival and Functional Recovery and the Influence of Transcriptomic Response Fludrocortisone 50 mcg daily, Fludrocortisone 100 mcg daily, Placebo - Septic Shock | Phase 3 | Recruiting | The George Institute | 2200 | 2026-10-16 | 2026-10-30 |
| Systematic Adjunction of Vasopressine in Septic Shock Vasopressin administration, Sodium chloride administration - Septic Shock | Phase 3 | Recruiting | Assistance Publique Hopitaux De Marseille | 120 | 2026-03-24 | 2026-10-26 |
| Early Methylene Blue in the Microhemodynamics of Septic Patients Methylene blue infusion - Septic Shock, Hypoperfusion | Phase 2 / Phase 3 | Recruiting | Centro de Estudos e Pesquisa em Emergencias Medicas e Terapia Intensiva | 50 | 2026-01-09 | 2026-03-27 |
| Weaning Approaches for Vasopressin in Sepsis Titrated weaning of vasopressin., Abrupt weaning of vasopressin. - Septic Shock | Phase 3 | Recruiting | Hospital Nossa Senhora da Conceicao | 82 | 2025-10-01 | 2026-01-02 |
| Norepinephrine and Vasopressin for Rescue Versus Early Vasopressin for Vasopressor Dependent Sepsis Early Vasopressin, Norepinephrine and Vasopressin for Rescue - Septic Shock | Phase 3 | Recruiting | Hospital do Coracao | 2800 | 2024-11-21 | 2026-01-30 |
| LANdiolol MIcrocirculatory Effects During Septic chOc (MILANOS) Landiolol - Septic Shock | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 44 | 2022-07-18 | 2025-08-01 |
| Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility echocardiography, Landiolol - Septic Shock, Tachycardia | Phase 3 | Recruiting | Centre Hospitalier Universitaire, Amiens | 360 | 2021-02-01 | 2025-08-24 |
| Stress Hydrocortisone In Pediatric Septic Shock Hydrocortisone, sodium succinate, Normal saline - Septic Shock | Phase 3 | Recruiting | Jerry Zimmerman | 500 | 2019-03-11 | 2025-10-30 |
Shock, Septic (8) · Diabetes Insipidus (2) · Sepsis (2) · Critical Illness (1) · Tachycardia (1)
Infections (8) · Inflammation (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Shock (8) · Systemic Inflammatory Response Syndrome (8) · Sepsis (6) · Endocrine System Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Pituitary Diseases (2) · Urogenital Diseases (2) · Urologic Diseases (2)
landiolol (2) · Fludrocortisone (1) · Hydrocortisone (1) · Methylene Blue (1) · Norepinephrine (1) · Phenothiazines (1) · Saline Solution (1) · Vasopressins (1)
Assistance Publique - Hôpitaux de Paris (1) · Assistance Publique Hopitaux De Marseille (1) · Centre Hospitalier Universitaire, Amiens (1) · Centro de Estudos e Pesquisa em Emergencias Medicas e Terapia Intensiva (1) · Hospital Nossa Senhora da Conceicao (1) · Hospital do Coracao (1) · Jerry Zimmerman (1) · The George Institute (1)
Brazil (4) · France (3) · Australia (1) · Canada (1) · Israel (1) · Japan (1) · Malaysia (1) · Pakistan (1) · Saudi Arabia (1) · Singapore (1) · United States (1) · Vietnam (1)
Bruno M Tomazini, MD (1) · David Wypij, PhD (1) · Jerry J Zimmerman MD, MD, PhD (1) · Kusum Menon, MD, MSc (1) · Machado R Flavia, PhD (1) · Michael Agus, MD (1) · Mihir R Atreya, MD, MPH (1)
PMID 19926252, PMID 28750598, PMID 28861671, PMID 29328496, PMID 29784057, PMID 30798676, PMID 31958982, PMID 32842024, PMID 35331049, PMID 36621622, PMID 38213315, PMID 38240508, PMID 40310269, PMID 41504572, PMID 41504575, PMID 9054839
R01HD096901 (1)