13 completed, 2 not yet recruiting, 2 unknown, 1 withdrawn. 13 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 9, Not yet recruiting 2, Unknown 2 |
| Phase 2 | 1 | Withdrawn 1 |
Follow Root Canal Therapy: new trials by email Literature Review of Root Canal Therapy trials Research Report on Root Canal Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mineral Trioxide Aggregate (MTA) vs Gutta-Percha for Non-Surgical Endodontic Retreatment in Teeth With Apical Lesions Mineral trioxide aggregate (MTA) group, Gutta-percha group - Periapical Diseases, Root Canal Therapy | Not applicable | Not yet recruiting | University of Santiago de Compostela | 58 | 2026-03-01 | 2026-03-23 |
| Comparison of Endodontic Flare up in Single Visit Root Canal Treatment Versus Multiple Visit Root Canal Treatment in Patients Visiting Scd, Swat. single visit root canal treatment, Multiple visit root canal treatment - Postoperative Complication, Root Canal Therapy | Not applicable | Not yet recruiting | College of Physicians and Surgeons Pakistan | 344 | 2026-01-01 | 2025-05-15 |
| Treatment Durations for Endodontic Procedures Root Canal Therapy | Completed | Uşak University | 102 | 2025-02-01 | 2026-08-24 | |
| Prospective Evaluation of Clinical Endodontic Performance Assessment Methods Not applicable- observational study - Root Canal Therapy | Completed | Aristotle University Of Thessaloniki | 201 | 2025-01-30 | 2026-06-02 | |
| Effect of Sonic Activation of Irrigant on Post Operative Pain After Root Canal Treatment endoactivator - Post Operative Pain, Root Canal Therapy | Not applicable | Completed | CMH Lahore Medical College and Institute of Dentistry | 58 | 2025-01-01 | 2025-10-01 |
| MB2 Canals in Pediatric Maxillary First Molars Stepwise MB2 Clinical Confirmation Protocol - Root Canal Therapy | Not applicable | Completed | Sümeyra Akkoç | 77 | 2023-10-01 | 2026-09-08 |
| Factors Affecting Success and Survival Rates in Root Canal Retreatment radiological and clinical examination - Root Canal Therapy, Root Canal Retreatment | Not applicable | Completed | Trakya University | 408 | 2023-06-01 | 2025-06-05 |
| Effects of Two Different Physical Therapy Protocols After an Endodontic Intervention Manual Therapy + Dry Needling, Manual Therapy - Root Canal Therapy, Endodontically Treated Teeth | Not applicable | Completed | Universidad de Zaragoza | 29 | 2022-03-07 | 2022-11-08 |
| Vital Pulp Therapy vs. Root Canal Treatment in Mature Teeth With Irreversible Pulpitis VPT Group and RCT Group - Pulpitis - Irreversible, Pulpitis | Not applicable | Completed | Universidad Central de Venezuela | 43 | 2021-01-01 | 2026-01-21 |
| Postoperative Pain Assessment After Using Different Kinematics Root canal therapy - Root Canal Therapy | Not applicable | Completed | Ain Shams University | 120 | 2020-02-01 | 2021-07-27 |
| Novel Collagen Scaffold vs Conventional Scaffold in Regeneration of Human Dental Pulp Tissue Collagen-hydroxyapatite scaffold (Syn-Oss), Collagen Scaffold (Colla-Plug) - Root Canal Therapy | Phase 2 | Withdrawn | University of Alabama at Birmingham | 2019-04-01 | 2019-05-23 | |
| Comparision of Non Surgical Retreatment and Endodontic Surgery of Failed Root Canal Treated Teeth surgical treatment, Non surgical retreatment - Root Canal Therapy, Periapical Periodontitis | Not applicable | Unknown | Postgraduate Institute of Dental Sciences Rohtak | 86 | 2018-01-01 | 2019-04-17 |
| Clinical Applicability of PBSCIMMO as a Single Material in Endodontic Obturations Gutta Percha and AHPLUS cement (group A), PBS CIMMO cement (group B) - Root Canal Therapy | Not applicable | Unknown | Universidade do Vale do Sapucai | 70 | 2017-11-09 | 2018-06-06 |
| Apical Size and Root Canal Treatment Success Trial (AS-RCT Trial) final apical size instrumentation - Root Canal Therapy | Not applicable | Completed | University of Washington | 35 | 2016-08-05 | 2022-02-24 |
| Sonendo GentleWave™ System for Treatment in Molar Teeth Requiring Root Canal Therapy Sonendo GentleWave™ System - Root Canal Therapy | Not applicable | Completed | Sonendo, Inc. | 69 | 2014-07-01 | 2023-01-31 |
| Antimicrobial Pastes and Clinical Cases of Apexogenesis Apexification - Apexification, Root Canal Therapy | Not applicable | Completed | Adriana Kelly de Sousa Santiago Barbosa | 14 | 2011-11-25 | 2017-04-13 |
| DPBRN Persistent Pain and Root Canal Therapy Root Canal Therapy, Persistent Tooth Pain | Completed | Dental Practice-Based Research Network | 500 | 2010-08-01 | 2011-09-20 | |
| DPBRN Peri-operative Pain and Root Canal Therapy Post-operative Tooth Pain, Root Canal Therapy | Completed | Dental Practice-Based Research Network | 500 | 2010-07-01 | 2011-09-20 |
Pain, Postoperative (3) · Dental Caries (1) · Dental Pulp Necrosis (1) · Periapical Abscess (1) · Periapical Diseases (1) · Periapical Periodontitis (1) · Postoperative Complications (1) · Pulpitis (1) · Tooth, Nonvital (1)
Stomatognathic Diseases (6) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Tooth Diseases (4) · Dental Pulp Diseases (3) · Jaw Diseases (3) · Mouth Diseases (3) · Neurologic Manifestations (3) · Pain (3) · Periodontal Diseases (3) · Postoperative Complications (3) · Signs and Symptoms (3) · Periapical Diseases (2) · Periodontitis (2) · Abscess (1)
Apexification (1) · Dry Needling (1) · Gutta-Percha (1) · Musculoskeletal Manipulations (1) · Physical Examination (1) · Root Canal Therapy (1) · Surgical Procedures, Operative (1)
Dental Practice-Based Research Network (2) · Adriana Kelly de Sousa Santiago Barbosa (1) · Ain Shams University (1) · Aristotle University Of Thessaloniki (1) · CMH Lahore Medical College and Institute of Dentistry (1) · College of Physicians and Surgeons Pakistan (1) · Postgraduate Institute of Dental Sciences Rohtak (1) · Sonendo, Inc. (1) · Sümeyra Akkoç (1) · Trakya University (1) · Universidad Central de Venezuela (1) · Universidad de Zaragoza (1) · Universidade do Vale do Sapucai (1) · University of Alabama at Birmingham (1) · University of Santiago de Compostela (1)
United States (5) · Turkey (Türkiye) (3) · Brazil (2) · Denmark (2) · Spain (2) · Egypt (1) · Greece (1) · India (1) · Pakistan (1) · Venezuela (1)
Donald R Nixdorf, DDS, MS (2) · Ahmed Hashem, PhD (1) · Dan Miller (1) · Daniela F Veiga, MD,PhD (1) · David Clanton, DMD (1) · Imran Khan, BDS FCPS (1) · Nikolaos Economides (1) · Paul D Eleazer, DDS (1) · Rubia Boczar (1) · Vanessa Chrepa, DDS, MS (1)
PMID 20433980, PMID 24767551, PMID 25190605, PMID 25355775, PMID 26335907, PMID 41062676
U01DE016747 (2)