1622 completed, 373 unknown, 207 terminated, 117 recruiting. 464 Not applicable, 426 Phase 2, 361 Phase 3, 285 Phase 1, 257 Phase 4.
Follow Rheumatoid Arthritis: new trials by email Literature Review of Rheumatoid Arthritis trials Research Report on Rheumatoid Arthritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Open-label Study of GC012F in Rheumatoid Arthritis. LD and GC012F CAR-T Cell Injection, GC012F CAR-T Cell Injection - Rheumatoid Arthritis | Early Phase 1 | Withdrawn | Institute of Hematology & Blood Diseases Hospital, China | 2027-12-01 | 2026-06-10 | |
| Safety and Tolerability of a Single Intravenous Infusion of BX-U001 in Refractory Rheumatoid Arthritis hUC-MSC suspension, Placebo - Rheumatoid Arthritis | Phase 1 | Not yet recruiting | Baylx Inc. | 16 | 2026-12-01 | 2025-12-23 |
| A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune Diseases PF-08154225 - Systemic Lupus Erythematosus, Rheumatoid Arthritis | Phase 1 / Phase 2 | Not yet recruiting | Pfizer | 54 | 2026-11-19 | 2026-10-01 |
| A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases BMS-986553 - Systemic Lupus Erythematosus, Sjögren's Disease | Phase 1 | Not yet recruiting | Bristol-Myers Squibb | 60 | 2026-10-30 | 2026-10-14 |
| Pain Phenotyping of Rheumatic Diseases - An Observational Study Bedside quantitative sensory testing - Rheumatic Diseases, Lupus Erythematosus, Systemic | Not yet recruiting | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 225 | 2026-10-27 | 2026-10-22 | |
| Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic Patients Meibomian Gland Dysfunction, Dry Eye Syndromes | Not yet recruiting | Assiut University | 150 | 2026-10-01 | 2026-09-09 | |
| Serum Asprosin, Metabolic Syndrome, and Cardiometabolic Risk in Rheumatoid Arthritis Rheumatoid Arthritis, Metabolic Syndrome | Not yet recruiting | Assiut University | 75 | 2026-10-01 | 2026-08-31 | |
| Development and Evaluation of the Effectiveness of the SMART-HAND Protocol for Hand Rehabilitation in Patients With Rheumatoid Arthritis SMART-HAND Protocol, Conventional Hand Rehabilitation, Joint Protection and Ergonomic Education - Rheumatoid Arthritis, Rheumatoid Arthritis (RA | Not applicable | Not yet recruiting | Istanbul University - Cerrahpasa | 132 | 2026-10-01 | 2026-08-14 |
| Subclinical Hypothyroidism and Disease Activity in Rheumatoid Arthritis Rheumatoid Arthritis, Subclinical Hypothyroidism | Not yet recruiting | Assiut University | 150 | 2026-10-01 | 2026-08-31 | |
| A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the Body HBM7020 - Rheumatoid Arthritis, Systemic Lupus Erythematosus | Phase 1 | Recruiting | Otsuka Pharmaceutical Development & Commercialization, Inc. | 63 | 2026-09-24 | 2026-10-13 |
| Foot Core Exercise Training With Telerehabilitation Asynchronous exercise group, Synchronous exercise group - Rheumatoid Arthritis, Foot Core | Not applicable | Suspended | Pamukkale University | 18 | 2026-09-24 | 2026-03-19 |
| Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research Pericarditis, Tako-TSUBO Cardiomyopathy | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 300 | 2026-09-01 | 2026-08-10 | |
| Efficacy and Safety of Telitacicept in the Treatment of Refractory Rheumatoid Arthritis Telitacicept 160mg, Standard therapy - Difficult-to-treat Rheumatoid Arthritis, Rheumatoid Arthritis | Phase 2 | Recruiting | Peking University People's Hospital | 420 | 2026-09-01 | 2026-09-01 |
| Disulfiram in Rheumatoid Arthritis Placebo, Disulfiram (DSF) - Rheumatoid Arthritis, Inflammation | Phase 2 | Not yet recruiting | University of Oklahoma | 20 | 2026-09-01 | 2026-07-27 |
| Subclinical Renal Dysfunction in Rheumatoid Arthritis Rheumatoid Arthritis, Renal Dysfunction | Not yet recruiting | Assiut University | 120 | 2026-09-01 | 2026-09-09 | |
| Study of PTC844 in Participants With Active Rheumatoid Arthritis PTC844, Placebo - Rheumatoid Arthritis | Phase 2 | Not yet recruiting | PTC Therapeutics | 75 | 2026-08-31 | 2026-08-21 |
| A Phase 1, First-in-Human Study of CND319 in Healthy Participants and Patients With Rheumatic Diseases CND319 - Healthy Participants Study, Rheumatoid Arthritis | Phase 1 | Recruiting | Candid Therapeutics | 105 | 2026-07-22 | 2026-10-21 |
| Natrunix in Combination With Methotrexate for Rheumatoid Arthritis Treatment Natrunix 400 mg, Placebo, Methotrexate (MTX) - Rheumatoid Arthritis | Phase 2 | Not yet recruiting | XBiotech, Inc. | 108 | 2026-07-15 | 2025-12-09 |
| Phase 1b/2 Study of IV Sarilumab in Adult With RA Sarilumab, SAR153191 SC, Sarilumab, SAR153191 IV - Rheumatoid Arthritis | Phase 1 / Phase 2 | Recruiting | Sanofi | 140 | 2026-07-02 | 2026-10-13 |
| Faecal Microbiota Transplantation in Patients With Refractory Rheumatoid Arthritis lyophilised oral capsules with faecal microbiota, Placebo capsules - Rheumatoid Arthritis | Phase 2 | Recruiting | Peking Union Medical College Hospital | 40 | 2026-07-01 | 2026-09-21 |
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Arthritis, Rheumatoid (2506) · Osteoarthritis (180) · Arthritis (155) · Arthritis, Psoriatic (117) · Spondylitis, Ankylosing (95) · Lupus Erythematosus, Systemic (87) · Osteonecrosis (78) · Autoimmune Diseases (54) · Inflammation (51) · Motor Activity (51) · Crohn Disease (47) · Rheumatic Diseases (40) · Spondylarthritis (40) · Joint Diseases (39) · Pain (38)
Skin and Connective Tissue Diseases (2506) · Immune System Diseases (2499) · Connective Tissue Diseases (2493) · Musculoskeletal Diseases (2486) · Joint Diseases (2467) · Rheumatic Diseases (2466) · Autoimmune Diseases (2452) · Arthritis (2351) · Bone Diseases (289) · Pathological Conditions, Signs and Symptoms (284) · Pathologic Processes (190) · Spinal Diseases (186) · Spondylitis (180) · Skin Diseases (177) · Spondylarthropathies (157)
Methotrexate (233) · tocilizumab (153) · Adalimumab (134) · Etanercept (116) · Rituximab (83) · Abatacept (77) · Infliximab (66) · Certolizumab Pegol (63) · tofacitinib (48) · Folic Acid (32) · golimumab (31) · Hydroxychloroquine (27) · baricitinib (27) · sarilumab (27) · Antirheumatic Agents (26)
Hoffmann-La Roche (184) · Bristol-Myers Squibb (79) · Pfizer (75) · Zimmer Biomet (56) · Amgen (45) · Assiut University (37) · AstraZeneca (36) · Abbott (33) · AbbVie (30) · Eli Lilly and Company (28) · AbbVie (prior sponsor, Abbott) (27) · Assistance Publique - Hôpitaux de Paris (23) · Sanofi (23) · University Hospital, Montpellier (23) · Genentech, Inc. (21)
United States (755) · France (280) · Germany (266) · United Kingdom (240) · Poland (209) · Spain (186) · Canada (179) · China (162) · Hungary (156) · Czechia (149) · Italy (147) · Mexico (147) · Russia (143) · Belgium (142) · South Korea (132)
PMID 27338778, PMID 29244149, PMID 30649524, PMID 36526796, PMID 36600185, PMID 36601090, PMID 36931693, PMID 32816215, PMID 33127856, PMID 34870800, PMID 25047021, PMID 28143815, PMID 34041702, PMID 39192350, PMID 31610021, PMID 34706874, PMID 36205910, PMID 37747626, PMID 29463520, PMID 22491018, PMID 30219772, PMID 33115760, PMID 36125701, PMID 36715850, PMID 36754548, PMID 37308218, PMID 37945286, PMID 37982966, PMID 38958913, PMID 40875187, PMID 24429164, PMID 24498318, PMID 29246162, PMID 29329602, PMID 30058112, PMID 32414425, PMID 34519964, PMID 36413080, PMID 36794283, PMID 39981557, PMID 42142212, PMID 25749867, PMID 27586634, PMID 27696724, PMID 27889300, PMID 29076110, PMID 30842122, PMID 31087226, PMID 31958281, PMID 32100960
2009 (24), 2016 (20), 2008 (19), 2015 (18), 2014 (15), 2005 (9), 2017 (9), 2019 (9), 2018 (7), 2025 (7), 2023 (5), 2004 (4), R01AR056702 (2), F31AT003362 (1), F32HL097461 (1)