25 completed, 9 unknown, 8 recruiting, 2 enrolling by invitation. 9 Not applicable, 8 Phase 4, 5 Phase 2, 1 Phase 1, 1 Phase 3.
Follow Renal Replacement Therapy: new trials by email Literature Review of Renal Replacement Therapy trials Research Report on Renal Replacement Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Machine Learning and Artificial Intelligence Algorithms to Optimize the Performance and Delivery of Acute Dialysis intermittent OR continuous renal replacement therapies - Renal Dialysis, Renal Replacement Therapy | Not yet recruiting | University of Alberta | 7500 | 2026-10-01 | 2026-09-24 | |
| FST Analysis Supporting Timely Therapy and Risk Assessment Via Clinical Decision Support for Kids Furosemide Stress Test Clinical Decision Support Tool - Acute Kidney Injury, Renal Replacement Therapy | Recruiting | Children's Hospital Medical Center, Cincinnati | 120 | 2026-05-27 | 2026-07-22 | |
| Amino Acid (15) Peritoneal Dialysis Solution for Nutritional Improvement in Peritoneal Dialysis Patients amino acid (15) peritoneal dialysis solution - End-stage Renal Disease (ESRD), Peritoneal Dialysis (PD) | Phase 4 | Enrolling by invitation | Shanghai 10th People's Hospital | 50 | 2026-05-01 | 2026-04-28 |
| Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America Dialysis, Critically Ill Acute Kidney Injury | Recruiting | University of Alabama at Birmingham | 1000 | 2026-03-01 | 2026-03-12 | |
| Analgesia Nociception Index to Explore Autonomic Nervous System in Patients With Continuous Renal Replacement Therapy Critically Ill, Renal Replacement Therapy | Recruiting | Hospices Civils de Lyon | 30 | 2026-01-09 | 2026-01-15 | |
| Hyperoxia vs Normoxia During Cardiopulmonary Bypass Hyperoxia group, Normoxia group (control) - AKI, Renal Replacement Therapy | Not applicable | Completed | University of Padova | 104 | 2025-07-01 | 2026-04-03 |
| The Cost-effectiveness of Artificial Intelligence Acute Kidney Injury Prediction Auxiliary Software (Acura AKI) Acura AKI - Acute Kidney Injury, Intensive Care | Not applicable | Recruiting | Huede Healthtech Co., Ltd. | 3600 | 2024-10-17 | 2024-11-12 |
| Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis Fexofenadine, Gabapentin - Uremic Pruritus, Chronic Kidney Disease-associated Pruritus | Phase 4 | Completed | Tanta University | 60 | 2024-07-01 | 2025-04-27 |
| Evaluation of Integrated Versus Parallel Connection for Renal Replacement Therapy in ECMO Patients Parallel connection, Integrated connection - Venoarterial Extracorporeal Membrane Oxygenation, Renal Replacement Therapy | Not applicable | Recruiting | Hospices Civils de Lyon | 158 | 2024-02-07 | 2026-01-20 |
| Albumin To Enhance Recovery After Acute Kidney Injury 20-25% Albumin fluid (100 mL), 0.9% Normal Saline (100 mL) - Acute Kidney Injury, Renal Replacement Therapy | Phase 4 | Recruiting | Ottawa Hospital Research Institute | 856 | 2023-11-02 | 2025-05-01 |
| Citrate Anticoagulation in Renal Replacement Therapy: Impact of a High Post-filter Calcium Target on Efficacy Citrate - Renal Replacement Therapy | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 108 | 2023-07-01 | 2025-08-22 |
| Aminoglycoside Administration in Septic Patients Continuous Renal Replacement Therapy - Sepsis, Septic Shock | Not applicable | Recruiting | University of Thessaly | 50 | 2023-06-02 | 2024-01-26 |
| Renal Replacement Therapies Decision Aids Web-based patient decision aid, Written health education leaflets - End-stage Renal Disease, Renal Replacement Therapy | Not applicable | Unknown | China Medical University Hospital | 70 | 2022-12-01 | 2022-12-28 |
| A Clinical Study to Evaluate the Efficacy, Safety and PK/PD Profiles of Anticoagulation of HSK36273 for Injection in Continuous Renal Replacement Therapy Subjects HSK36273, Heparin sodium - Renal Replacement Therapy | Phase 2 | Unknown | Haisco Pharmaceutical Group Co., Ltd. | 156 | 2022-11-01 | 2022-11-02 |
| REnal reCOVery After ECMO for Cardiogenic Shock (RECOVECMO) standard of care - Cardiogenic Shock, Renal Replacement Therapy | Completed | University Hospital, Bordeaux | 93 | 2022-01-01 | 2024-05-16 | |
| Machine Learning Predict Renal Replacement Therapy After Cardiac Surgery Machine Learning, Acute Kidney Injury | Completed | Chinese PLA General Hospital | 2108 | 2020-09-01 | 2021-08-02 | |
| Impact of Dialysis Modality on Coagulation and Platelet Function dialysis mode - Renal Replacement Therapy | Completed | Seoul National University Hospital | 60 | 2020-08-04 | 2023-12-28 | |
| Comparison of Biphozyl® and Phoxilium® as a Replacement Fluid During CVVH for AKI in Adults and Their Effects on pH-, Bicarbonate-levels and Respiratory Situation CVVH with Phoxilium® in the first 48h after randomization, CVVH with Biphozyl® in the first 48h after randomization, CVVH with Phoxilium® in the second 48h after randomization (after previous 48h with Biphozyl®) - Critically Ill, Acute Kidney Injury | Phase 2 | Completed | Medical University Innsbruck | 88 | 2020-08-01 | 2024-03-13 |
| Urinary Biomarkers for AKI Diagnosis in Patients With SARS-CoV-2 (COVID-19) [TIMP-2]*[IGFBP-7] - COVID-19, Renal Replacement Therapy | Completed | University Hospital, Montpellier | 100 | 2020-03-01 | 2020-07-29 | |
| AGNES - Aging Nephropathy Study, a Prospective Observational Cohort of Chronic Kidney Disease in Elderly Patients no intervention - Chronic Kidney Diseases, Elderly | Completed | University of Sao Paulo General Hospital | 151 | 2019-09-01 | 2025-04-03 |
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Acute Kidney Injury (23) · Kidney Failure, Chronic (9) · Critical Illness (4) · Renal Insufficiency, Chronic (4) · Renal Insufficiency (3) · Sepsis (3) · Arteriovenous Fistula (2) · Hypotension (2) · Infections (2) · Acute Coronary Syndrome (1) · Anemia (1) · Arrhythmias, Cardiac (1) · COVID-19 (1) · Carcinoma, Renal Cell (1) · Cardiovascular Diseases (1)
Female Urogenital Diseases (34) · Female Urogenital Diseases and Pregnancy Complications (34) · Male Urogenital Diseases (34) · Urogenital Diseases (34) · Urologic Diseases (34) · Kidney Diseases (33) · Renal Insufficiency (30) · Pathological Conditions, Signs and Symptoms (21) · Pathologic Processes (19) · Disease Attributes (15) · Chronic Disease (12) · Renal Insufficiency, Chronic (8) · Cardiovascular Diseases (5) · Vascular Diseases (5) · Heart Diseases (3)
Saline Solution (3) · Renal Replacement Therapy (2) · Adrenal Cortex Hormones (1) · Amino Acids (1) · Basiliximab (1) · Bicarbonates (1) · Blood Specimen Collection (1) · Cefazolin (1) · Citric Acid (1) · Continuous Renal Replacement Therapy (1) · Cyclosporine (1) · Dialysis (1) · Dialysis Solutions (1) · Everolimus (1) · Gabapentin (1)
Children's Hospital Medical Center, Cincinnati (2) · Hospices Civils de Lyon (2) · Ottawa Hospital Research Institute (2) · Seoul National University Hospital (2) · University Hospital, Montpellier (2) · Amsterdam UMC, location VUmc (1) · Assistance Publique - Hôpitaux de Paris (1) · B.C. van Jaarsveld (1) · Centre Hospitalier Universitaire Vaudois (1) · China Medical University Hospital (1) · Chinese PLA General Hospital (1) · Cleveland Clinic Abu Dhabi (1) · Drexel University (1) · European Society of Intensive Care Medicine (1) · Haisco Pharmaceutical Group Co., Ltd. (1)
France (8) · China (5) · United States (5) · Belgium (4) · Canada (4) · Brazil (3) · Germany (3) · Netherlands (3) · South Korea (3) · Switzerland (3) · Taiwan (3) · Australia (2) · Austria (2) · Chile (2) · Colombia (2)
Ahmed M Hussein, PhD (1) · Anne Kuitunen, MD, PhD (1) · Brigit C van Jaarsveld, MD, PhD (1) · Chun-Te Huang (1) · Dong Ki Kim, MD, PhD (1) · Edward G Clark, MD MSc FRCPC (1) · Edward G Clark, MD, MSc (1) · Epaminondas Zakynthinos, Prof (1) · Ian C Chetter, MBChB FRCS (1) · Islam Ghazi, PharmD (1) · Javier A Neyra, MD, MSCS (1) · Jiaqi Qian, MD (1)
PMID 36416787, PMID 18854418, PMID 21388319, PMID 22070937, PMID 26567256, PMID 26762150, PMID 28151412, PMID 29321041, PMID 29424935, PMID 29752413, PMID 30617611, PMID 30723975, PMID 31152476, PMID 31161046, PMID 31299919, PMID 31480045, PMID 31672793, PMID 32633157, PMID 33160321, PMID 34216395, PMID 34519356, PMID 34620664, PMID 34902089, PMID 36447221, PMID 39327056, PMID 40177120, PMID 40305120, PMID 40759107, PMID 41247497, PMID 42342404
P50DK096418 (1)