2 completed, 2 enrolling by invitation, 1 recruiting, 1 unknown. 6 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 2, Enrolling by invitation 2, Recruiting 1, Unknown 1 |
Follow REM Sleep Behavior Disorder: new trials by email Literature Review of REM Sleep Behavior Disorder trials Research Report on REM Sleep Behavior Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MIBG in Aging and Neurologic Disorders meta-iodobenzylguanidine (MIBG) (123I), 123I-MIBG scintigraphy - Lewy Body Disease, Dementia | Phase 4 | Enrolling by invitation | Mayo Clinic | 50 | 2023-05-08 | 2026-07-30 |
| Multimodal Image Technologies Investigate the Role and Mechanism of Probiotics in Improving RBD with Parkinson's Disease PD-RBD, iRBD - Parkinson Disease, Movement Disorders | Phase 4 | Recruiting | Beijing Friendship Hospital | 120 | 2022-09-01 | 2024-12-02 |
| Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate Sodium Oxybate, Placebo - REM Sleep Behavior Disorder, Parkinson Disease | Phase 4 | Completed | Stanford University | 24 | 2019-09-10 | 2023-05-10 |
| Effect of Slow-release Melatonin (Circadin®) Therapy on Idiopathic RBD: a Pilot Study Circadin, Placebo - REM Sleep Behavior Disorder | Phase 4 | Unknown | Seoul National University Hospital | 30 | 2016-01-01 | 2017-04-28 |
| DaTSCAN Imaging in Aging and Neurodegenerative Disease I-123 Ioflupane solution injection prior to SPECT scan (DaTscan), Single photon emission computed tomography (SPECT) scan - Dementia, Parkinsonism | Phase 4 | Enrolling by invitation | Mayo Clinic | 500 | 2011-10-01 | 2026-03-10 |
| Study to Determine Whether Ramelteon Helps People With REM Sleep Behavior Disorder ramelteon, placebo - REM Sleep Behavior Disorder | Phase 4 | Completed | Sleep Medicine Centers of WNY | 20 | 2008-01-01 | 2011-07-25 |
Cognitive Dysfunction (2) · Dementia (2) · Parkinson Disease (2) · Parkinsonian Disorders (2) · Lewy Body Disease (1) · Movement Disorders (1)
Mental Disorders (6) · Nervous System Diseases (6) · Parasomnias (6) · REM Sleep Parasomnias (6) · Sleep Wake Disorders (6) · Basal Ganglia Diseases (4) · Brain Diseases (4) · Central Nervous System Diseases (4) · Movement Disorders (3) · Neurodegenerative Diseases (3) · Synucleinopathies (3) · Cognition Disorders (2) · Neurocognitive Disorders (2) · Parkinsonian Disorders (2)
3-Iodobenzylguanidine (1) · Iodine-123 (1) · Melatonin (1) · Radionuclide Imaging (1) · Sodium Oxybate (1) · Tomography, Emission-Computed, Single-Photon (1) · ioflupane (1) · ramelteon (1)
Mayo Clinic (2) · Beijing Friendship Hospital (1) · Seoul National University Hospital (1) · Sleep Medicine Centers of WNY (1) · Stanford University (1)
United States (4) · China (1) · South Korea (1)
Bradley Boeve, MD (2) · Daniel I Rifkin, MD (1) · Emmanuel During, MD (1)
PMID 29560382, PMID 32198310, PMID 33348363, PMID 33408148, PMID 33422890, PMID 36844148, PMID 37052688