86 recruiting, 74 unknown, 49 completed, 31 not yet recruiting. 85 Phase 2, 78 Not applicable, 32 Phase 3, 13 Phase 1, 2 Phase 4.
Follow Radiotherapy: new trials by email Literature Review of Radiotherapy trials Research Report on Radiotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Risk Factors of Jaw Osteoradionecrosis in Oral Cavity Cancer Patients Post-Radiotherapy Osteoradionecrosis, Radiotherapy | Not yet recruiting | AO Innovation Translation Center | 1000 | 2027-03-01 | 2026-09-23 | |
| Anti-PCSK9 Antibody Tafolecimab and Anti-PD-1 Antibody Sintilimab Combined With Neoadjuvant Chemoradiotherapy for pMMR/ MSS Locally Advanced Rectal Cancer : A Prospective, Multicenter, Randomized, Open-Label, Parallel-Controlled Trial Short-course radiotherapy, CAPOX (oxaliplatin/capecitabine), Sintilimab - Local Advanced Rectal Cancer, PD-1 Inhibitor | Phase 3 | Not yet recruiting | Guangdong Provincial People's Hospital | 148 | 2027-01-01 | 2026-07-07 |
| A Prospective, Biomarker-Stratified Phase 2 Study: β-Hydroxybutyrate as a Predictive Biomarker for Short-Course Radiotherapy Followed by Chemotherapy Plus PD-1 Inhibitor Versus Chemotherapy Alone in Locally Advanced Rectal Cancer Short-course radiotherapy, Capecitabine, Oxaliplatin - Rectal Cancer, Radiotherapy | Phase 2 | Not yet recruiting | Tao Zhang | 144 | 2026-11-01 | 2026-10-06 |
| Nimotuzumab Plus Radiotherapy in Elderly Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Nimotuzumab - Head & Neck Cancer, Radiotherapy | Phase 2 | Not yet recruiting | Ke Hu | 46 | 2026-09-10 | 2026-09-15 |
| Short-Course Radiotherapy Followed by CAPOX With or Without Iparomlimab and Tuvonralimab in pMMR/MSS Locally Advanced Rectal Cancer Short-Course Radiotherapy, Consolidation treatment (With ICIs), Consolidation treatment (Without ICIs) - Local Advanced Rectal Cancer, Radiotherapy | Phase 3 | Recruiting | Shandong Cancer Hospital and Institute | 180 | 2026-08-15 | 2026-08-18 |
| Low-dose Thoracic Radiotherapy Followed by Adebrelimab Plus Chemotherapy, and Then Sequential Maintenance Therapy With Adebrelimab for Extensive-stage Small Cell Lung Cancer Etoposide, Cisplatin, Carboplatin - Lung, Radiotherapy | Phase 2 | Recruiting | Jiangmen Central Hospital | 43 | 2026-07-20 | 2026-09-22 |
| Quality of Life of Patients Who Have Undergone Bilateral Mastectomy Surgery Date, Age | Not yet recruiting | University Hospital, Grenoble | 115 | 2026-07-10 | 2026-07-15 | |
| A Prospective, Single-Arm Clinical Study of a Dietary Supplement for the Prevention of Acute Radiation-Induced Rectal Injury During Neoadjuvant Chemoradiotherapy for Rectal Cancer Tributyrin - Radiotherapy, Radiation-Induced Complications | Not applicable | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 23 | 2026-07-01 | 2026-09-03 |
| Effect of the MIROKI Companion Robot on Anxiety in Pediatric Radiotherapy Pediatric Oncology, Radiotherapy | Not yet recruiting | Institut du Cancer de Montpellier - Val d'Aurelle | 6 | 2026-07-01 | 2026-06-12 | |
| Real-world Study on the Efficacy, Safety, and Prognostic Factors of Immune Checkpoint Inhibitors Combined With Radiotherapy in Patients With Malignant Tumors: A Prospective Non-interventional Clinical Study Radiotherapy, Immune Checkpoint Inhibitors (ICIs) | Not yet recruiting | Sichuan University | 200 | 2026-06-30 | 2026-06-24 | |
| Centrally Confined 8Gy/1f to Tumor Core Followed by Concurrent Chemoradiotherapy for Unresectable Stage III NSCLC Centrally Confined 8 Gy/1 Fraction Immune-Priming Radiotherapy to the Tumor Core Followed by Definitive Concurrent Chemoradiotherapy - Locally-Advanced Non-Small Cell Lung Cancer, Radiotherapy | Phase 1 | Not yet recruiting | Anhui Provincial Hospital | 24 | 2026-06-01 | 2026-04-13 |
| Effects of Moderate-intensity Interval Aerobic Exercise (MIIAE) on Inflammatory, Immune, Metabolic, Physical Fitness, and Quality of Life Parameters in Breast Cancer Patients Undergoing Radiotherapy. Moderate-Intensity Interval Aerobic Exercise - Radiotherapy, Inflamation | Not applicable | Not yet recruiting | Universidad Francisco de Vitoria | 40 | 2026-06-01 | 2026-05-13 |
| Patient Position Monitoring System for Beam Gated Radiation Therapy of Malignancies of the Chest and Upper Abdomen Patient Position Monitoring System - Radiotherapy, Radiotherapy, Image-Guided | Recruiting | Washington University School of Medicine | 20 | 2026-05-20 | 2026-05-22 | |
| Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC Sintilimab + IL-2 Combined with CAPOX, Short-course low-dose radiotherapy, Short-course standard-dose radiotherapy - Rectal Cancer, Radiotherapy | Phase 2 | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 122 | 2026-05-20 | 2026-06-15 |
| A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in Locally Advanced Rectal Cancer Short-course radiotherapy, Long-course radiotherapy, Capecitabine - Rectal Cancer, Total Neoadjuvant Therapy | Phase 3 | Recruiting | Tao Zhang | 444 | 2026-05-15 | 2026-05-13 |
| Comparison Between Virtual vs in Person on Treatment Follow-up Visits of Radiotherapy Radiotherapy | Recruiting | Shaukat Khanum Memorial Cancer Hospital & Research Centre | 180 | 2026-05-11 | 2026-07-24 | |
| MRinRT: Swansea University and SWWCC Collaboration Study. MRI - Carcinoma, Glioblastoma | Not yet recruiting | Swansea Bay University Health Board | 165 | 2026-05-01 | 2026-04-30 | |
| Establishment of a Prospective Clinical Cohort of Small Cell Lung Cancer Patients Receiving Radiotherapy-Involved Comprehensive Treatment radiatherapy, and chemotherapy with or without immunotherapy as clinical practice - Small Cell Lung Cancer ( SCLC ), Radiotherapy | Recruiting | Shanghai Chest Hospital | 500 | 2026-04-01 | 2026-05-04 | |
| Phase III, Multicenter, Randomized Controlled Clinical Study of Three-Dimensional Radiotherapy for Primary Tumors in Non-Oligometastatic Stage IV Non-Small Cell Lung Cancer Three-Dimensional Radiotherapy for Primary lungTumors - Non Small Cell Lung Cancer Metastatic, Radiotherapy | Not applicable | Not yet recruiting | Guizhou Medical University | 200 | 2026-03-30 | 2026-03-10 |
| Omitting Clinical Target Volume in Radical Treatment of Unresectable Stage III Non-small Cell Lung Cancer IMRT+adjuvant immunotherapy - Immunotherapy, Intensity Modulated Radiation Therapy | Not yet recruiting | Xinqiao Hospital of Chongqing | 60 | 2026-02-01 | 2025-07-14 |
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Rectal Neoplasms (23) · Breast Neoplasms (17) · Carcinoma, Hepatocellular (14) · Head and Neck Neoplasms (14) · Neoplasms (13) · Brain Neoplasms (12) · Carcinoma, Non-Small-Cell Lung (12) · Nasopharyngeal Carcinoma (12) · Esophageal Neoplasms (11) · Prostatic Neoplasms (11) · Uterine Cervical Neoplasms (11) · Squamous Cell Carcinoma of Head and Neck (9) · Lung Neoplasms (8) · Colorectal Neoplasms (7) · Radiation Injuries (7)
Neoplasms (190) · Neoplasms by Site (181) · Digestive System Diseases (68) · Digestive System Neoplasms (65) · Neoplasms by Histologic Type (55) · Gastrointestinal Diseases (50) · Neoplasms, Glandular and Epithelial (49) · Gastrointestinal Neoplasms (47) · Carcinoma (43) · Head and Neck Neoplasms (37) · Intestinal Neoplasms (30) · Rectal Diseases (30) · Intestinal Diseases (29) · Urogenital Diseases (27) · Urogenital Neoplasms (27)
Radiotherapy (40) · Drug Therapy (17) · Immune Checkpoint Inhibitors (13) · Radiosurgery (10) · Cisplatin (8) · Capecitabine (7) · sintilimab (7) · Carboplatin (5) · Immunotherapy (5) · Oxaliplatin (5) · Radiation Dose Hypofractionation (5) · Radiotherapy, Intensity-Modulated (5) · toripalimab (5) · Chemoradiotherapy (4) · Neoadjuvant Therapy (4)
Fudan University (12) · Sun Yat-sen University (12) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (9) · Sixth Affiliated Hospital, Sun Yat-sen University (9) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (7) · Peking University Third Hospital (7) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (6) · Shandong Cancer Hospital and Institute (5) · Chinese Academy of Medical Sciences (4) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (4) · Nanfang Hospital, Southern Medical University (4) · Peking Union Medical College Hospital (4) · University Hospital, Ghent (4) · Xinqiao Hospital of Chongqing (4) · Centre Francois Baclesse (3)
China (133) · France (18) · Italy (16) · United States (11) · Belgium (8) · Denmark (6) · Turkey (Türkiye) (6) · Germany (5) · Netherlands (5) · South Korea (5) · Canada (4) · Switzerland (4) · Norway (3) · Poland (3) · Taiwan (3)
Alessio G Morganti, MD (8) · Jinbo Yue, Doctor (3) · Lei Li, M.D. (3) · Changqing Jing, Professor (2) · Francesco Cellini, MD (2) · Jianping Xiao, Dr (2) · Kuaile Zhao, MD (2) · Ming Kuang, PhD (2) · Tao Zhang, MD (2) · Xiaolong Fu, MD (2) · Xuezhang Duan, MD (2) · Zhenyu Lin (2) · Zuping Lian, MD (2) · Alan C. Hartford, MD PhD FACR (1)
PMID 33538338, PMID 14722039, PMID 18846565, PMID 20171515, PMID 20879569, PMID 21489705, PMID 23164174, PMID 24890347, PMID 25175042, PMID 25407874, PMID 26829933, PMID 27441744, PMID 27488294, PMID 27789196, PMID 27871280, PMID 28640703, PMID 29122701, PMID 29156912, PMID 32556627, PMID 10364237, PMID 10530742, PMID 10946929, PMID 11173128, PMID 11355268, PMID 11420508, PMID 11491236, PMID 11744442, PMID 12459649, PMID 12750523, PMID 12771885, PMID 14988393, PMID 15716838, PMID 15840561, PMID 17854932, PMID 18212313, PMID 18832646, PMID 18963537, PMID 19168203, PMID 19362783, PMID 19616743, PMID 19632069, PMID 20041484, PMID 20047800, PMID 20378407, PMID 20559064, PMID 20675070, PMID 20800404, PMID 20882668, PMID 20963353, PMID 21149658
2016 (1), 2017 (1), 75N91019C00054-0-9999-1 (1), P30CA086862 (1)