30 completed, 8 recruiting, 8 unknown, 7 terminated. 34 Not applicable, 11 Phase 2, 9 Phase 3, 4 Phase 1, 1 Early Phase 1.
Follow Radiation Dermatitis: new trials by email Literature Review of Radiation Dermatitis trials Research Report on Radiation Dermatitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral or Topical Catechins for Radiation Dermatitis Epicatechin, Epigallocatechin Gallate (EGCG), Microcrystalline Cellulose NF (placebo) - Radiation Dermatitis Acute, Radiation Dermatitis | Phase 3 | Enrolling by invitation | CARLOS FRANCISCO SAAVEDRA GARCIA | 162 | 2026-10-01 | 2026-09-11 |
| Efficacy of Superoxide Dismutase Spray in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer . Placebo Spray, SOD spray - Radiation Dermatitis | Not applicable | Withdrawn | West China Hospital | 2026-02-10 | 2026-06-23 | |
| Efficacy of Superoxide Dismutase in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer . Saline Spray, SOD spray - Radiation Dermatitis | Not applicable | Withdrawn | West China Hospital | 2026-02-04 | 2026-06-23 | |
| Mepitel Film Breast Breast Cancer, Radiation Dermatitis | Recruiting | National University Hospital, Singapore | 60 | 2025-11-12 | 2026-07-27 | |
| ROS-Scavenging Nanozyme Combined With Thermotherapy Alleviate Radiation Dermatitis in Patients With Head and Neck Cancer Photo-responsive nanozyme - Radiation Dermatitis | Not applicable | Recruiting | West China Hospital | 5 | 2025-07-25 | 2026-04-15 |
| ROS-scavenging Amino Acid-derived Lipids for the Prevention and Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer Amino acid-derived lipids, standard of care - Radiation Dermatitis | Not applicable | Recruiting | West China Hospital | 40 | 2025-07-23 | 2026-04-15 |
| Novel ROS-scavenging Nanoenzymes for the Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer ROS-scavenging Nanoenzymes, Standard of care - Radiation Dermatitis | Not applicable | Recruiting | West China Hospital | 30 | 2025-07-15 | 2025-08-07 |
| M-PART in Head and Neck Cancer Patients Treated With KeraStat Cream for Acute Radiation Dermatitis KeraStat cream, M-PART Assessments via MyCap, Clinical Assessments - Radiation Dermatitis | Not applicable | Completed | Wake Forest University Health Sciences | 16 | 2025-05-08 | 2026-07-06 |
| Modulating the Skin Microbiome to Prevent Radiation Dermatitis in Breast Cancer Skin Repairing Cream, Cetaphil® Moisturizing Cream as Inactive Control - Skin Microbiome, Breast Cancer | Phase 3 | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 326 | 2025-04-10 | 2025-07-15 |
| Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position Topical Betamethasone - Breast Cancer, Radiation Dermatitis | Phase 3 | Recruiting | Sunnybrook Health Sciences Centre | 276 | 2025-02-26 | 2025-05-21 |
| Effect of a Mushroom Extract-Containing Topical Cosmetic Formulation During Breast Radiotherapy Mushroom extract-containing topical cosmetic formulation, Usual moisturizing cosmetic care - Radiation Dermatitis, Breast Cancer | Not applicable | Completed | Hifas da Terra S.L. | 50 | 2024-11-20 | 2026-10-13 |
| Prospective Assessment of Acute Skin Toxicities in Breast Cancer Patients Undergoing Retreatment with 40 Gy in 15 Fractions Radiation Therapy Breast Cancer, Radiation Dermatitis | Unknown | Sunnybrook Health Sciences Centre | 30 | 2024-08-07 | 2024-12-11 | |
| Efficacy of Fullerene in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer . Fullerene cream, Trolamine (Biafine) - Radiation Dermatitis | Not applicable | Completed | West China Hospital | 132 | 2024-08-01 | 2025-06-04 |
| Efficacy Study With StrataXRT for the Prophylaxis of Radiation Dermatitis in Adjuvant Breast Radiation Treatment in Large Breasted Women Using a Prone Technique StrataXRT - Breast Cancer, Radiation Dermatitis | Not applicable | Active not recruiting | Sunnybrook Health Sciences Centre | 20 | 2024-02-14 | 2025-05-21 |
| Efficacy and Safety of Hyperbaric Oxygen Therapy for Radiation Dermatitis in Patients with Localized Breast Cancer hyperbaric oxygen chamber - Breast Cancer, Radiation Dermatitis | Not applicable | Completed | Ilsan Cha hospital | 30 | 2023-11-06 | 2024-11-20 |
| Clinical Investigation on the Treatment of Radiation Induced Dermatitis With FR-101 Chest Dressing FR-101 Chest Dressing - Breast Cancer, Radiation Dermatitis | Not applicable | Unknown | China Medical University Hospital | 30 | 2023-09-18 | 2023-09-18 |
| Topical Steroids & Bacterial Decolonization for Radiation Dermatitis Bacterial decolonization, Mometasone furoate 0.1% cream, Bacterial decolonization and Mometasone furoate 0.1% cream - Radiation Dermatitis | Phase 2 | Withdrawn | Montefiore Medical Center | 2023-09-01 | 2023-12-22 | |
| Retrospective Cohort Study Comparing a Novel Gel Dressing vs SoC in the Treatment of Radiation Dermatitis StrataXRT, Calendula, Aquaphor - Radiation Dermatitis | Completed | Stratpharma AG | 344 | 2023-05-01 | 2024-02-01 | |
| Topical Dermaprazole for Radiation Dermatitis in Breast Cancer Patients (TOPAZ) Dermaprazole 1%, Dermaprazole 2% - Radiation Dermatitis, Breast Cancer | Phase 1 / Phase 2 | Terminated | Baylor College of Medicine | 3 | 2023-04-24 | 2026-02-17 |
| Evaluation of the Effect of Nigella Sativa for the Prophylaxis to Radiation Induced Dermatitis in Breast Cancer Patients Imtenan Oil, Baraka Capsules - Radiation Dermatitis | Phase 2 | Completed | German University in Cairo | 132 | 2023-01-24 | 2024-02-23 |
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Radiodermatitis (64) · Breast Neoplasms (26) · Head and Neck Neoplasms (7) · Dermatitis (5) · Radiation Injuries (4) · Stomatitis (3) · Erythema (2) · Eczema (1) · Fibrosis (1) · Neoplasms (1) · Radiation Fibrosis Syndrome (1) · Skin Diseases (1)
Skin and Connective Tissue Diseases (64) · Wounds and Injuries (64) · Skin Diseases (63) · Radiation Injuries (60) · Dermatitis (59) · Neoplasms (31) · Neoplasms by Site (31) · Breast Diseases (26) · Pathological Conditions, Signs and Symptoms (4) · Mouth Diseases (3) · Stomatognathic Diseases (3) · Pathologic Processes (2) · Signs and Symptoms (2) · Skin Manifestations (2) · Fibrosis (1)
Low-Level Light Therapy (4) · Petrolatum (3) · Standard of Care (3) · Aloe vera gel (1) · Biafine (1) · Catechin (1) · Dimethyl Sulfoxide (1) · Gels (1) · Melatonin (1) · Mometasone Furoate (1) · Radiation (1) · Sodium Chloride (1) · Sodium Hypochlorite (1) · Zinc Oxide (1) · cetyl alcohol, propylene glycol, sodium lauryl sulfate non-lipid cleansing lotion (1)
Sunnybrook Health Sciences Centre (6) · West China Hospital (6) · Mayo Clinic (3) · Stratpharma AG (3) · AceTech (2) · China Medical University Hospital (2) · Jessa Hospital (2) · Montefiore Medical Center (2) · Wake Forest University Health Sciences (2) · AC Camargo Cancer Center (1) · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) (1) · Baylor College of Medicine (1) · CARLOS FRANCISCO SAAVEDRA GARCIA (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Centre Leon Berard (1)
United States (20) · Canada (7) · China (7) · Israel (5) · France (4) · Belgium (3) · Brazil (2) · Spain (2) · Taiwan (2) · Australia (1) · Denmark (1) · Egypt (1) · Germany (1) · Mexico (1) · Singapore (1)
Edward LW Chow, MBBS (4) · Xingchen Peng (3) · Jeroen Mebis, MD, PhD (2) · Amy Paller, MD (1) · Annelies Maes, MD (1) · Beth McLellan, MD (1) · Carmen Palacios, MD; PhD; MMSc; genetics (1) · Christin A. Harless, M.D. (1) · Daniel A Hamstra, MD, PhD (1) · Dennis B Zetner, MD (1) · Diana Matchiavsky, MD (1) · Dirk Rades, Professor (1) · Douglas Fife, MD (1) · Elizabeth Nichols, MD (1) · Glauco Baiocchi, MD, PhD (1)
PMID 16980242, PMID 18474463, PMID 26328937, PMID 32450921, PMID 36493331, PMID 37140904, PMID 37441546, PMID 37819539, PMID 39292351, PMID 39316164, PMID 40259026, PMID 41861269
P30CA012197 (2), 2018 (1)