34 completed, 13 unknown, 6 recruiting, 3 terminated. 61 Phase 2, 17 Phase 3, 10 Phase 1.
Follow Quality of Life: new trials by email Literature Review of Quality of Life trials Research Report on Quality of Life
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Shuganhuazhuo Formula for Advanced Hepatocellular Carcinoma With Damp-Heat Syndrome Shuganhuazhuo Formula, Targeted therapy, Immunotherapy - HCC - Hepatocellular Carcinoma, Chinese Herbal Medicine | Phase 2 | Not yet recruiting | Xiang-Qian | 120 | 2027-09-01 | 2026-08-27 |
| CBD Supplementation in Brazilian Jiu-Jitsu Athletes CBD Isolate 100mg BID, Placebo - Pro and Anti Inflamatory Cytokines, Pain | Phase 2 / Phase 3 | Not yet recruiting | Associação Pan-Americana Multidisciplinar de Endocanabinologia | 100 | 2027-01-01 | 2026-07-27 |
| Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease ACT for SCD - Race-related Stress, Depression, Anxiety | Phase 1 / Phase 2 | Recruiting | Children's Hospital Los Angeles | 66 | 2025-04-01 | 2026-05-06 |
| A Study of Enalapril in Treatment of Venous Malformations Enalapril - Venous Malformation, Pain | Phase 2 | Recruiting | Oslo University Hospital | 12 | 2025-02-01 | 2025-04-02 |
| Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. Radiation Therapy, Chemoradiotherapy, Consolidation Chemotherapy - Rectal Cancer, Total Neoadjuvant Treatment | Phase 2 / Phase 3 | Recruiting | National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos | 400 | 2025-01-06 | 2026-05-11 |
| Lysergic Acid Diethylamide (LSD) in Palliative Care Lysergic Acid Diethylamide Tartrate - Palliative Care, Pain | Phase 2 | Recruiting | University Hospital, Basel, Switzerland | 60 | 2024-06-09 | 2026-04-29 |
| Improvement of Quality of Life by Cannabinoids in Oncologic Patients Cannabisextrakt Avextra 10/10 Lösung - Medical Oncology, Palliative Care | Phase 2 | Terminated | University Hospital Schleswig-Holstein | 79 | 2024-04-08 | 2026-10-16 |
| Polyamine Treatment in Elderly Patients With Coronary Artery Disease Spermidine, Placebo - Ischemic Heart Disease, Myocardial Infarction | Phase 2 | Completed | University of Aarhus | 187 | 2024-01-01 | 2026-07-01 |
| Effectiveness of Low-dose Naltrexone in Patients With Different Types of Vulvodynia Naltrexone Hydrochloride - Vulvodynia, Naltrexone | Phase 2 | Recruiting | Medical University of Lublin | 300 | 2023-05-31 | 2023-07-21 |
| Efficacy of a Self-advocacy Serious Game Intervention Strong Together serious game, Enhanced Care as Usual - Self-Management, Quality of Life | Phase 2 | Completed | University of Pittsburgh | 344 | 2022-08-22 | 2026-10-23 |
| Statin Impact on Hepatic Decompensation Atorvastatin 20mg, Placebo - Quality of Life, the Incidence of Whole Complications Resultant From Decompensated Liver | Phase 2 / Phase 3 | Completed | Tanta University | 100 | 2022-06-15 | 2026-09-14 |
| Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy Accelerated Partial Breast Irradiation (APBI), tamoxifen, anastrozole, exemestane, letrozole, fulvestrant, toremifene - Breast Cancer, Quality of Life | Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 90 | 2022-05-17 | 2026-05-26 |
| Safety and Efficacy Evaluation of the P2Et Extract in Patients With Breast Cancer P2Et (Caesalpinia spinosa extract), Placebo - Breast Cancer, Quality of Life | Phase 2 | Unknown | Hospital Universitario San Ignacio | 58 | 2022-03-01 | 2022-08-09 |
| Naldebain for Pain Management of Laparoscopic Cholecystectomy Dinalbuphine sebacate, Placebo solution - Pain, Postoperative, Pain, Chronic | Phase 2 / Phase 3 | Completed | E-DA Hospital | 80 | 2021-08-30 | 2022-04-20 |
| Artificial Intelligence Supporting CAncer Patients Across Europe - the ASCAPE Project ASCAPE-based follow-up strategy - Breast Cancer, Prostate Cancer | Phase 2 | Active not recruiting | Region Örebro County | 500 | 2021-02-01 | 2024-11-19 |
| Safety and Efficacy of Inhaled Cannabis For the Uncontrolled Pain Relief in Patients With Advanced Cancer PPP001, Placebo - Cancer Pain, Quality of Life | Phase 2 | Unknown | Tetra Bio-Pharma | 78 | 2020-07-30 | 2021-09-16 |
| Vaginal Prolapse Surgery Accompanied by Mid Urethral Sling Versus no Sling for Reduction of Postoperative Incontinence Retro pubic sling - Stress Urinary Incontinence, Vaginal Hysterectomy | Phase 2 / Phase 3 | Unknown | B.P. Koirala Institute of Health Sciences | 56 | 2020-01-01 | 2020-02-05 |
| Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease Disulfiram - Fatigue, Quality of Life | Phase 1 / Phase 2 | Completed | Research Foundation for Mental Hygiene, Inc. | 11 | 2019-07-31 | 2025-01-09 |
| Anlotinib Hydrochloride Versus Imatinib Mesylate in Locally Advanced, Unresectable or Metastatic Chordoma Anlotinib Hydrochloride - Effect of Drugs, Quality of Life | Phase 2 | Unknown | Peking University People's Hospital | 60 | 2019-07-18 | 2019-08-05 |
| Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis combined radiotherapy and MR-HIFU - Bone Metastases, Bone Neoplasm | Phase 1 / Phase 2 | Completed | UMC Utrecht | 10 | 2019-04-11 | 2024-02-07 |
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Breast Neoplasms (6) · Pain (5) · Fatigue (4) · Anxiety Disorders (3) · Depression (3) · Motor Activity (3) · Neoplasms (3) · Radiation Injuries (3) · Carcinoma, Hepatocellular (2) · Cognitive Dysfunction (2) · Colonic Neoplasms (2) · Colorectal Neoplasms (2) · Constipation (2) · Gastrointestinal Stromal Tumors (2) · Inflammation (2)
Pathological Conditions, Signs and Symptoms (24) · Signs and Symptoms (20) · Neoplasms (18) · Neoplasms by Site (17) · Behavior (12) · Pathologic Processes (11) · Neurologic Manifestations (9) · Urogenital Diseases (9) · Digestive System Diseases (8) · Neoplasms by Histologic Type (8) · Female Urogenital Diseases (7) · Female Urogenital Diseases and Pregnancy Complications (7) · Male Urogenital Diseases (7) · Breast Diseases (6) · Digestive System Neoplasms (6)
Chemoradiotherapy (2) · Oxaliplatin (2) · Acupuncture, Ear (1) · Alanine (1) · Amino Acids, Essential (1) · Anastrozole (1) · Atorvastatin (1) · Auriculotherapy (1) · BID protein, human (1) · Behavior Therapy (1) · Botulinum Toxins (1) · Capecitabine (1) · Cholecalciferol (1) · Cisplatin (1) · Consolidation Chemotherapy (1)
Northwestern University (2) · University of Sao Paulo (2) · AC Camargo Cancer Center (1) · Affiliated Cancer Hospital & Institute of Guangzhou Medical University (1) · Affiliated Hospital of North Sichuan Medical College (1) · Asklepios Kliniken Hamburg GmbH (1) · Associação Pan-Americana Multidisciplinar de Endocanabinologia (1) · B.P. Koirala Institute of Health Sciences (1) · Centers for Disease Control and Prevention (1) · Centre Hospitalier Universitaire de Besancon (1) · Children's Hospital Los Angeles (1) · Clinical Research Organization, Dhaka, Bangladesh (1) · Copenhagen University Hospital, Rigshospitalet (1) · E-DA Hospital (1) · Faculdade de Medicina do ABC (1)
United States (17) · Brazil (6) · China (5) · Canada (3) · Denmark (3) · Egypt (2) · France (2) · Germany (2) · Norway (2) · Taiwan (2) · Bangladesh (1) · Colombia (1) · Greece (1) · Israel (1) · Lithuania (1)
Willis G. Parsons, MD, PC (2) · Anita Kinney (1) · Art F Kramer, PhD (1) · Audrius Dulskas, PhD (1) · Barbara I Karp, M.D. (1) · Bernard Fortin, MD MSc (1) · Bin Qi, M. D. (1) · Birthe D Pedersen (1) · Brian A Fallon, MD (1) · Celso Carvalho, Dr. (1) · Christina Shannon, ND (1) · Claudia H Arce Salinas, MD (1) · Daiyuan Ma, M.D (1) · Dana Casey, MD (1) · Dong-ping Chen, M. D. (1)
PMID 11226762, PMID 11764222, PMID 12686700, PMID 12697943, PMID 1352024, PMID 15139073, PMID 16766588, PMID 17187507, PMID 17530482, PMID 18525044, PMID 19037667, PMID 20972805, PMID 21533811, PMID 21682864, PMID 22488022, PMID 22888417, PMID 22893165, PMID 23358260, PMID 23599170, PMID 23620504, PMID 23644268, PMID 24761161, PMID 24915873, PMID 25012726, PMID 25029046, PMID 25106522, PMID 25566379, PMID 26241603, PMID 26733251, PMID 26829246, PMID 27020111, PMID 28150436, PMID 30280129, PMID 30574050, PMID 30911656, PMID 30911669, PMID 31289238, PMID 31343947, PMID 3281702, PMID 32979134, PMID 33326662, PMID 33931037, PMID 35446854, PMID 3544842, PMID 36379436, PMID 37354201, PMID 37670337, PMID 38695191, PMID 38775255, PMID 39260823
2023 (1), R01AG046401 (1), R01AR044020 (1), R01NR013906 (1), R21CA135250 (1)