21 completed, 9 recruiting, 8 not yet recruiting, 3 active not recruiting. 33 Not applicable, 3 Phase 4, 2 Phase 1, 1 Phase 2.
Follow Probiotic: new trials by email Literature Review of Probiotic trials Research Report on Probiotic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Barley and Kefir on Gut Microbiota in Physically Active Adults Barley, Kefir - Gut Microbiota Diversity and Composition, Gut Microbiota Modulation | Not applicable | Recruiting | Western Norway University of Applied Sciences | 80 | 2026-09-07 | 2026-10-23 |
| Probiotic Role in Prevention of Ventilator Associated Pneumonia in Critically- Ill Children Admitted at Pediatric Intensive Care Unit Probiotics, Standard management - Probiotic, Ventilator Associated Pneumonia | Not applicable | Recruiting | Tanta University | 68 | 2026-07-01 | 2026-09-29 |
| Probiotic Intervention on the Development of Allergic Diseases in Infants Exposed to Antibiotics Early in Life Probiotic mixture, Placebo - Antibiotic, Allergic Diseases | Not applicable | Not yet recruiting | Peking University Third Hospital | 400 | 2026-04-17 | 2026-05-11 |
| Clinical Trial of Lactiplantibacillus Plantarum Dad-13 on Gut Microbiota Profile and Performance in Adolescent Athletes Probiotic Lactiplantibacillus plantarum Dad-13 - Athlete, Probiotic | Not applicable | Not yet recruiting | Gadjah Mada University | 30 | 2026-04-13 | 2026-03-23 |
| Probiotics, Antibiotics and the Post-Antibiotic Microbiota Lab4S, Placebo - Probiotic, Microbiome | Not applicable | Not yet recruiting | Cultech Ltd | 50 | 2026-04-13 | 2026-03-18 |
| Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer Biolosion (oral probiotic compound preparation) - Breast Cancer, Triple Negative Breast Cancer (TNBC) | Phase 2 | Recruiting | Sun Yat-sen University | 192 | 2026-04-01 | 2026-04-01 |
| Probiotics in COPD: Effects on Symptoms, Lung Function, and Inflammation Probiotic Capsule, placebo capsule - COPD, COPD (Chronic Obstructive Pulmonary Disease) | Not applicable | Enrolling by invitation | University Hospital of Split | 60 | 2026-03-08 | 2026-04-21 |
| Efficacy of Symprove Probiotics in Coeliac Disease Symprove Probiotic - Coeliac Disease, Probiotic | Not applicable | Recruiting | Sheffield Teaching Hospitals NHS Foundation Trust | 24 | 2026-01-29 | 2026-03-17 |
| Probiotics for Women Lab4 + Lactobacillus gasseri and Lactobacillus crispatus, Placebo - Probiotic, Microbiome | Not applicable | Completed | Cultech Ltd | 40 | 2026-01-22 | 2026-08-20 |
| Patient-Reported Probiotic Use During Periodontal Therapy in Periodontitis non surgical periodontal therapy - Periodontitis, Probiotic | Completed | Medipol University | 130 | 2025-12-20 | 2026-06-01 | |
| Multi-strain Probiotic Effects on Self-Reported Constipation Multi-strain probiotics - Constipation, Probiotic | Not applicable | Completed | Dr Anthony Hobson | 20 | 2025-10-03 | 2026-10-23 |
| Probiotics and Active Aging: Enhancing Gut Health Dietary Supplement, Placebo, Structured Physical Activity Program - Gut -Microbiota, Older People | Not applicable | Not yet recruiting | Jose Luis Felipe | 90 | 2025-09-01 | 2025-06-24 |
| Probiotic-Based Versus Ethyl Lauroyl Arginate-Containing Mouthwashes on Streptococcus Mutans Counts, Dental Plaque Accumulation, and Salivary pH in a Group of Egyptian School Children Probiotic mouthwash, Ethyl lauroyl arginate mouthwash, Professional prophylaxis (scaling + polishing) - Probiotic, Ethyl Lauroyl Arginate | Not applicable | Recruiting | Al-Azhar University | 66 | 2025-08-15 | 2026-01-21 |
| Effect of Probiotic's Consumption on Several Markers in Perforated Appendix Patients With Diffuse Peritonitis Lactobacillus plantarum sp Probiotic, Placebo Group - Appendicitis With Perforation, Appendectomy | Not applicable | Active not recruiting | Universitas Padjadjaran | 50 | 2025-08-01 | 2026-03-31 |
| Developing Precision Microbiota-Based Cocktail Modification Therapy to Delay the Progression of Parkinson's Disease (PD) - Use Preclinical Human Trials to Confirm the Impact of the Optimal "Probiotic Y7, Tryptophan and Branched-chain Amino Acid" Cocktail Formula on Early Stage PD Patients Y7, Placebo - Parkinson Disease (PD), Gut Microbiota | Not applicable | Recruiting | Taipei Medical University | 120 | 2025-05-20 | 2026-06-02 |
| Probiotics for Preterm Infants Probiotic mix preparation, Bifidobacteria - Preterm Infant Feeding Outcomes, Probiotic | Not yet recruiting | Ankara City Hospital Bilkent | 100 | 2025-03-30 | 2025-03-20 | |
| Psychobiotics and Mental Health in Obese Women on a Weight-Loss Diet Psychobiotic Supplement, Placebo Supplement - Obesity, Mental Health | Not applicable | Completed | Medipol University | 40 | 2025-02-13 | 2025-09-05 |
| Efficacy and Safety of Oral Probiotics on Ocular Symptoms and Gut Microbiome of Children with Vernal Keratoconjunctivitis Probiotic, Placebo Drug - Probiotic, Ocular Surface Disease | Phase 1 | Not yet recruiting | Mohsen Pourazizi | 32 | 2025-02-01 | 2025-01-27 |
| Impact of Probiotics on Gut Microbiome During Antibiotic Prophylaxis in Elective Orthopedic Surgery Placebo Capsule, Probiotic with Human Milk Oligosaccharides (HMO) - Dysbiosis, Gut -microbiota | Phase 4 | Not yet recruiting | Acibadem Maslak Hospital | 60 | 2025-02-01 | 2025-01-24 |
| Probiotic and Prebiotic Use in Early Postoperative Period of Sleeve Gastrectomy Probiotic and Prebiotic - Sleeve Gastrectomy, Gastrointestinal Symptoms | Not applicable | Completed | Ayten Altunsaray | 60 | 2024-12-24 | 2026-10-15 |
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Periodontitis (3) · Constipation (2) · Insulin Resistance (2) · Motor Activity (2) · Parkinson Disease (2) · Psychological Well-Being (2) · Acne Vulgaris (1) · Appendicitis (1) · Breast Neoplasms (1) · COVID-19 (1) · Celiac Disease (1) · Cerebral Palsy (1) · Colic (1) · Common Cold (1) · Conjunctivitis, Allergic (1)
Pathological Conditions, Signs and Symptoms (7) · Infections (5) · Digestive System Diseases (4) · Nutritional and Metabolic Diseases (4) · Pathologic Processes (4) · Respiratory Tract Diseases (4) · Signs and Symptoms (4) · Stomatognathic Diseases (4) · Behavior (3) · Brain Diseases (3) · Central Nervous System Diseases (3) · Gastrointestinal Diseases (3) · Intestinal Diseases (3) · Lung Diseases (3) · Metabolic Diseases (3)
Probiotics (10) · Dietary Supplements (2) · Prebiotics (2) · Inulin (1) · Kefir (1) · Milk Proteins (1) · Tooth Exfoliation (1) · Yogurt (1) · guar gum (1) · maltodextrin (1)
Bogomolets National Medical University (2) · Clinica Universidad de Navarra, Universidad de Navarra (2) · Cultech Ltd (2) · Medipol University (2) · AYŞENUR ŞAHİN (1) · Acibadem Maslak Hospital (1) · Al-Azhar University (1) · Ankara City Hospital Bilkent (1) · Ayten Altunsaray (1) · Azienda Ospedaliero Universitaria Maggiore della Carita (1) · Bambino Gesù Hospital and Research Institute (1) · Beijing Friendship Hospital (1) · Benha University (1) · Chi-Chang Huang (1) · Chinese University of Hong Kong (1)
Turkey (Türkiye) (6) · Taiwan (5) · China (4) · Egypt (3) · Italy (3) · United Kingdom (3) · United States (3) · Bulgaria (2) · Indonesia (2) · Poland (2) · Spain (2) · Croatia (1) · Hong Kong (1) · Norway (1) · Thailand (1)
Gabriela Arias (2) · Idoia Ibero-Baraibar, PhD (2) · Roncesvalles Garayoa, PhD (2) · Alessandro Fiocchi, M.D. (1) · Alpdogan Kantarci (1) · Aybegum Kalyoncu Aycenk, Assistant Professor (1) · Blanca Martinez (1) · David S Sanders, MBChB, MD (1) · Emanuele Chisari, Dr., Ph.D. (1)
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