36 completed, 9 unknown, 4 terminated, 3 recruiting. 21 Not applicable, 10 Phase 2, 6 Phase 1, 5 Phase 3, 5 Phase 4.
Follow Primary Open-Angle Glaucoma: new trials by email Literature Review of Primary Open-Angle Glaucoma trials Research Report on Primary Open-Angle Glaucoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PureSee EDOF Versus ZCB00 Monofocal IOLs in Mild-to-Moderate Glaucoma TECNIS PureSee Intraocular Lens, TECNIS ZCB00 Monofocal Intraocular Lens - Primary Open-Angle Glaucoma | Not yet recruiting | Mann Eye Institute | 100 | 2026-12-02 | 2026-11-09 | |
| Combined Phacoemulsification-Goniotomy in Primary Open-Angle and Primary Angle-Closure Glaucoma Combined Phacoemulsification and Goniotomy - Primary Open-Angle Glaucoma, Primary Angle-Closure Glaucoma | Not applicable | Not yet recruiting | Assiut University | 70 | 2026-10-01 | 2026-09-16 |
| A Phase II Trial of G01 Eye Drops for Glaucomatous Optic Neuropathy G01 Eye Drops 100μg/ml, G01 Eye Drops 200μg/ml, Placebo of G01 Eye Drops - Primary Open-Angle Glaucoma, Optic Nerve Injury | Phase 2 | Recruiting | Qingdao WanMing BioCell Pharmaceutics Co.,Ltd. | 90 | 2026-03-18 | 2026-08-24 |
| Effects of Primary Open-angle Glaucoma on Visual-motor Coordination Primary Open-angle Glaucoma | Unknown | Zhongshan Ophthalmic Center, Sun Yat-sen University | 200 | 2024-11-21 | 2024-11-18 | |
| Safety and Tolerability of a Timolol Releasing Intraocular Implant in Subjects With Primary Open-angle Glaucoma TimoD implant, Injector system - Primary Open-angle Glaucoma | Phase 1 | Terminated | EyeD Pharma | 1 | 2023-03-01 | 2025-07-16 |
| MINIject Implantation Combined With Cataract Surgery in Patients With POAG and Cataract Phacoemulsification combined with minimally invasive glaucoma surgery (MIGS) - Primary Open-angle Glaucoma, Cataract | Not applicable | Enrolling by invitation | iSTAR Medical | 30 | 2023-01-18 | 2025-02-28 |
| GORE Glaucoma Drainage Implant Clinical Study Dominican Republic Gore Glaucoma Device Implant (GORE GDI) - Primary Open-angle Glaucoma | Not applicable | Active not recruiting | W.L.Gore & Associates | 30 | 2022-09-14 | 2026-02-19 |
| Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma Glycocheck, Ophthalmological examinations - Primary Open-angle Glaucoma, Glaucoma | Recruiting | Fondation Ophtalmologique Adolphe de Rothschild | 100 | 2022-05-06 | 2025-12-08 | |
| GlaucoT Glaucoma Treatment Glasses in the Treatment of Primary Open-Angle Glaucoma GlaucoT Glaucoma Treatment Device - Primary Open-Angle Glaucoma | Not applicable | Completed | Glaucot Teknoloji Anonim Sirketi | 15 | 2022-03-01 | 2024-11-18 |
| Effect of Acupuncture on Visual Acuity and Visual Field in Patients With Primary Open-angle Glaucoma Acupuncture - Primary Open-angle Glaucoma | Not applicable | Completed | China Medical University Hospital | 40 | 2022-02-28 | 2024-04-10 |
| Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyl Eybelis ophthalmic solution 0.002% - Normal Tension Glaucoma, Primary Open-angle Glaucoma | Phase 4 | Unknown | Santen Pharmaceutical Asia Pte. Ltd. | 150 | 2022-02-15 | 2022-03-15 |
| Switching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSD Switching the preserved prostaglandin analog-timolol FC to Fixalpost (preservative free prostaglandin analog-timolol FC) - Primary Open-angle Glaucoma, Ocular Hypertension | Not applicable | Unknown | Klinički Bolnički Centar Zagreb | 50 | 2021-03-08 | 2021-05-18 |
| BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular Hypertension BREMEN eye drops, Combigan® - Ocular Hypertension, Primary Open-angle Glaucoma | Phase 3 | Completed | EMS | 406 | 2021-02-01 | 2024-02-20 |
| Prevalence of Ocular Surface Disease in Malaysian Glaucoma Patients Primary Open-angle Glaucoma, Primary Angle-Closure Glaucoma | Unknown | Santen Pharma Malaysia Sdn Bhd | 400 | 2020-11-01 | 2020-10-30 | |
| Safety and Effectiveness of VISULAS Green Selective Laser Trabeculoplasty (SLT) selective laser trabeculoplasty (SLT) - Primary Open-angle Glaucoma | Not applicable | Completed | Carl Zeiss Meditec AG | 37 | 2020-06-30 | 2024-12-19 |
| PRESERFLO® MicroShunt Extension Study PRESERFLO® MicroShunt, Trabeculectomy - Primary Open-angle Glaucoma | Completed | InnFocus Inc. | 279 | 2020-05-22 | 2024-03-22 | |
| SIGHT Study: Cost-effectiveness of InnFocus Microshunt Implantation vs. Trabeculectomy. PRESERFLO Microshunt implantation, Trabeculectomy - Primary Open-angle Glaucoma | Not applicable | Unknown | Maastricht University Medical Center | 124 | 2020-02-01 | 2024-03-19 |
| Decorin in Sub Scleral Trabeculectomy Decorin, Mitomycin c - Primary Open-angle Glaucoma | Phase 1 | Unknown | Cairo University | 52 | 2019-09-01 | 2019-04-23 |
| Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertension Levobetaxolol eye drops, Betaxolol eye drops - Primary Open-angle Glaucoma, Ocular Hypertension | Phase 3 | Completed | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | 366 | 2019-01-04 | 2023-05-12 |
| A Clinical Study to Evaluate the Efficacy and Safety of CKD-351 CKD-351, Latanoprost, D930 - Primary Open-angle Glaucoma, Ocular Hypertension | Phase 3 | Unknown | Chong Kun Dang Pharmaceutical | 384 | 2018-12-07 | 2018-12-03 |
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Glaucoma, Open-Angle (57) · Ocular Hypertension (18) · Glaucoma (14) · Cataract (5) · Exfoliation Syndrome (3) · Low Tension Glaucoma (3) · Glaucoma, Angle-Closure (2) · Retinal Degeneration (2) · Sleep Apnea, Obstructive (2) · Choroidal Effusions (1) · Geographic Atrophy (1) · Optic Atrophy (1) · Optic Nerve Diseases (1) · Optic Nerve Injuries (1) · Vitamin D Deficiency (1)
Eye Diseases (57) · Glaucoma (43) · Ocular Hypertension (39) · Lens Diseases (5) · Nervous System Diseases (4) · Optic Nerve Diseases (4) · Uveal Diseases (4) · Iris Diseases (3) · Retinal Diseases (3) · Apnea (2) · Cranial Nerve Diseases (2) · Dyssomnias (2) · Eye Diseases, Hereditary (2) · Respiration Disorders (2) · Respiratory Tract Diseases (2)
Bimatoprost (5) · Latanoprost (4) · Trabeculectomy (4) · Cataract Extraction (3) · Timolol (3) · Brimonidine Tartrate (2) · Acupuncture Therapy (1) · Benzalkonium Compounds (1) · Brimonidine Tartrate, Timolol Maleate Drug Combination (1) · Continuous Positive Airway Pressure (1) · Culture Techniques (1) · Decorin (1) · Drugs, Investigational (1) · LX-7101 (1) · Lasers (1)
ForSight Vision5, Inc. (4) · Glaukos Corporation (4) · Alcon Research (2) · Wills Eye (2) · Allergan (1) · Aristotle University Of Thessaloniki (1) · Assiut University (1) · Cairo University (1) · Carl Zeiss Meditec AG (1) · Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation (1) · China Medical University Hospital (1) · Chong Kun Dang Pharmaceutical (1) · EMS (1) · EyeD Pharma (1) · Fondation Ophtalmologique Adolphe de Rothschild (1)
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Michelle Chen, PhD (4) · Kerry Stephens, O.D. (2) · Ahmed AM Gad, MD (1) · Alejo Peyret, PhD (1) · Alina K Drakon, MD (1) · Anastasios G Konstas, MD, PhD (1) · Anna Grau (1) · Ching-Liang Hsieh, Ph.D (1) · Constantine D Georgakopoulos, MD, PhD (1) · Daniel Grigera, PhD (1) · Daniel Lee, MD (1) · Dariusz Wozniak, MBBS, MRCP (1) · Doreen Schmidl, MD,PhD (1) · Eng Hui Gan, Specialist (1)
PMID 17191187, PMID 21851167, PMID 28454526, PMID 28528010, PMID 29781833, PMID 30488265, PMID 30727982, PMID 33469852, PMID 34041935, PMID 35076329, PMID 35943114, PMID 36572747, PMID 36721130, PMID 39510809, PMID 41737851
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