3 completed, 2 unknown, 1 terminated. 6 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 3, Unknown 2, Terminated 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
Follow Primary Open-angle Glaucoma: new trials by email Literature Review of Primary Open-angle Glaucoma trials Research Report on Primary Open-angle Glaucoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Tolerability of a Timolol Releasing Intraocular Implant in Subjects With Primary Open-angle Glaucoma TimoD implant, Injector system - Primary Open-angle Glaucoma | Phase 1 | Terminated | EyeD Pharma | 1 | 2023-03-01 | 2025-07-16 |
| Decorin in Sub Scleral Trabeculectomy Decorin, Mitomycin c - Primary Open-angle Glaucoma | Phase 1 | Unknown | Cairo University | 52 | 2019-09-01 | 2019-04-23 |
| Effectiveness and Safety of Adipose-Derived Regenerative Cells for Treatment of Glaucomatous Neurodegeneration Subtenon administration of autologous ADRC, Liposuction, ADRC isolation - Retinal Degeneration, Primary Open-Angle Glaucoma | Phase 1 / Phase 2 | Unknown | Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation | 16 | 2014-05-01 | 2017-07-21 |
| Intravitreal Mesenchymal Stem Cell Transplantation in Advanced Glaucoma. Intravitreal transplantation of mesenchymal stem cell, Culture and isolation of autologous bone-marrow mesenchymal stem cells - Retinal Degeneration, Primary Open-angle Glaucoma | Phase 1 | Completed | University of Sao Paulo | 2 | 2014-01-01 | 2019-07-08 |
| Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension LX7101 (0.125%), LX7101 (0.25%), LX7101 Vehicle - Primary Open-angle Glaucoma, Ocular Hypertension | Phase 1 / Phase 2 | Completed | Lexicon Pharmaceuticals | 63 | 2012-03-01 | 2015-09-14 |
| Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertension OPA-6566, Placebo, Latanoprost - Primary Open-angle Glaucoma, Ocular Hypertension | Phase 1 / Phase 2 | Completed | Kubota Vision Inc. | 160 | 2011-09-01 | 2014-03-11 |
Glaucoma, Open-Angle (6) · Glaucoma (2) · Ocular Hypertension (2) · Retinal Degeneration (2) · Optic Atrophy (1) · Optic Nerve Diseases (1)
Eye Diseases (6) · Glaucoma (4) · Ocular Hypertension (4) · Eye Diseases, Hereditary (2) · Retinal Diseases (2) · Cranial Nerve Diseases (1) · Nervous System Diseases (1)
Culture Techniques (1) · Decorin (1) · Drugs, Investigational (1) · LX-7101 (1) · Latanoprost (1) · Lipectomy (1) · Mitomycin (1)
Cairo University (1) · Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation (1) · EyeD Pharma (1) · Kubota Vision Inc. (1) · Lexicon Pharmaceuticals (1) · University of Sao Paulo (1)
United States (2) · Brazil (1) · Egypt (1) · Germany (1) · Russia (1)
Alina K Drakon, MD (1) · Ilya I Eremin, MD, PhD (1) · Jayter S Paula, MD (1) · Joel Freiman, M.D., MPH (1) · John W Chandler, MD (1) · Julia P Sotnikova, MD (1)