332 completed, 97 unknown, 91 recruiting, 41 not yet recruiting. 458 Not applicable, 39 Phase 2, 31 Phase 4, 21 Phase 3, 12 Phase 1.
Follow Prediabetes: new trials by email Literature Review of Prediabetes trials Research Report on Prediabetes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial of CGM Technology in Persons Living With Prediabetes Stelo CGM - Prediabetes | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 100 | 2027-04-01 | 2026-10-23 |
| Cardiometabolic & Cognitive Effects of Peanut Butter in Prediabetes Peanut butter, Usual diet - Prediabetes | Not applicable | Not yet recruiting | Penn State University | 56 | 2027-01-18 | 2026-07-20 |
| Time to Healthy Lifestyle Habit Using Digital Health Tools in Adults at Risk of Diabetes Hybrid digital intervention with personalized support., Standard lifestyle education - Prediabetes | Not applicable | Not yet recruiting | Imam Abdulrahman Bin Faisal University | 222 | 2027-01-01 | 2026-06-25 |
| Diabetes Prevention Through Genetics, Familial History and Behavior Change LEGACY DPP, DPP - Prediabetes, Weight Loss | Phase 2 / Phase 3 | Not yet recruiting | Morehouse School of Medicine | 400 | 2027-01-01 | 2026-10-20 |
| Optimizing Implementation of the Intensive Diabetes Prevention Program Standard IDPP, Optimized IDPP - Prediabetes, Diabetes Prevention | Not applicable | Not yet recruiting | The Hong Kong Polytechnic University | 170 | 2026-12-02 | 2026-09-17 |
| Continuous Glucose Monitoring and Dietary Self-Management in Adults in Namwon Continuous Glucose Monitoring With Application-Based Biofeedback, Common Standardized Education and Behavioral Goal Setting, Common Digital Health Program and Basic Health Counseling - Prediabetes, Dietary Self-Management | Not applicable | Not yet recruiting | Ji-Yeob Choi | 860 | 2026-11-02 | 2026-10-22 |
| Training Induced Muscle-Adipose EV Communication Acute Resistance Exercise - Prediabetes | Not applicable | Not yet recruiting | Yuan Wen | 40 | 2026-11-01 | 2026-10-02 |
| Evaluation of the Effectiveness of Implementing a Screening Strategy for the Diagnosis of Prediabetes and Type 2 Diabetes Mellitus in Primary Health Care in a Brazilian Municipality ARISE Strategy - Diabetes Mellitus (Type 2), Prediabetes | Not applicable | Not yet recruiting | epHealth | 45000 | 2026-11-01 | 2026-10-02 |
| LIfestyle MEtabotype Study B (LIME-B) βHB drink (ketone ester), Carbohydrate drink - Nutritional and Metabolic Diseases, Prediabetes | Not applicable | Recruiting | German Institute of Human Nutrition | 300 | 2026-10-26 | 2026-10-22 |
| LIfestyle MEtabotype Study A Nutritional and Metabolic Diseases, Prediabetes | Recruiting | German Institute of Human Nutrition | 300 | 2026-10-10 | 2026-10-09 | |
| Multimodal Risk Factor Graph Mapping, Metabolic Subtyping, and Digital Intelligent Chronic Disease Management for Prediabetes: An Integrated Cohort and Case-Control Clinical Study Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance) | Not yet recruiting | Nanjing Medical University | 30000 | 2026-10-08 | 2026-10-02 | |
| Pharmacist-Led Continuous Glucose Monitoring for Prediabetes Dexcom Stelo CGM - Prediabetes | Recruiting | University of South Florida | 40 | 2026-10-06 | 2026-10-07 | |
| Studies of Blood Glucose and the Microbiome in Tumors and Cysts of the Pancreas Pancreatic Neoplasms, Pancreatic Cysts | Not yet recruiting | Umeå University | 100 | 2026-10-01 | 2026-09-25 | |
| Precision Nutrition for Obesity and Prediabetes Prevention in Under-supported Communities Precision Nutrition Intervention, Standard Nutrition Counseling - Obesity & Overweight, Prediabetes | Not applicable | Not yet recruiting | Prairie View A&M University | 100 | 2026-10-01 | 2026-09-30 |
| Piloting FUERTE: Federally qUalified Health Centers Engaging Hispanic Men at Risk of diabeTEs FUERTE Arm, Standard care, No Intervention - Prediabetes | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 50 | 2026-10-01 | 2026-10-16 |
| Returning to Normoglycemia With Targeted Use of Real-time CGM Data and Nutrition-focused Lifestyle Changes CGM-guided care - Prediabetes | Not applicable | Not yet recruiting | HealthPartners Institute | 330 | 2026-10-01 | 2026-09-22 |
| Glycemic Impact of NNS Via the Gut Microbiome Sucralose - Prediabetes | Not applicable | Enrolling by invitation | Tufts University | 10 | 2026-10-01 | 2026-10-09 |
| Effects of Hourly Stair-Climbing Exercise Snacks on Metabolic and Vascular Health in Adults With Prediabetes Hourly 3-Minute Light Walking Breaks, Hourly Stair-Climbing Exercise Snacks - Prediabetes | Not applicable | Recruiting | St. Louis University | 20 | 2026-10-01 | 2026-09-29 |
| The Effect of Time-Restricted Eating in 24-hour Metabolic Homeostasis and Diurnal Rhythm Time restricted eating, Healthy Eating, Extended eating window - Obesity, Prediabetes | Not applicable | Not yet recruiting | Cambridge University Hospitals NHS Foundation Trust | 26 | 2026-09-15 | 2026-09-15 |
| Exocrine-Endocrine Pancreatic Crosstalk: Precision Pathways to Reframe Diabetes Pathophysiology Type 2 Diabetes Mellitus (T2DM), Chronic Pancreatitis | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 440 | 2026-09-01 | 2026-06-26 |
Showing 20 of 643. Sign in to see all of them.
Prediabetic State (643) · Obesity (173) · Diabetes Mellitus, Type 2 (138) · Diabetes Mellitus (106) · Overweight (90) · Insulin Resistance (81) · Glucose Intolerance (55) · Metabolic Syndrome (48) · Motor Activity (41) · Hypertension (32) · Cardiovascular Diseases (31) · Hyperglycemia (28) · Weight Loss (28) · Dyslipidemias (23) · Body Weight (20)
Endocrine System Diseases (640) · Nutritional and Metabolic Diseases (639) · Glucose Metabolism Disorders (634) · Metabolic Diseases (634) · Diabetes Mellitus (537) · Pathological Conditions, Signs and Symptoms (234) · Signs and Symptoms (215) · Nutrition Disorders (190) · Body Weight (189) · Overnutrition (187) · Hyperinsulinism (116) · Overweight (97) · Behavior (79) · Vascular Diseases (53) · Hyperglycemia (45)
Metformin (30) · Exercise (19) · Diet (15) · Continuous Glucose Monitoring (7) · Standard of Care (7) · Cholecalciferol (6) · dapagliflozin (6) · Diet Therapy (5) · Glucose Tolerance Test (5) · Resistance Training (5) · semaglutide (5) · Control Groups (4) · Diet, Carbohydrate-Restricted (4) · Diet, Ketogenic (4) · Diet, Mediterranean (4)
Johns Hopkins University (12) · Stanford University (9) · University of Toronto (9) · Ohio State University (8) · John Sievenpiper (7) · University of Alabama at Birmingham (7) · University of Michigan (7) · Diabetes Foundation, India (6) · German Institute of Human Nutrition (6) · University of Guadalajara (6) · University of Pittsburgh (6) · VA Office of Research and Development (6) · Indiana University (5) · Kaiser Permanente (5) · Midwest Center for Metabolic and Cardiovascular Research (5)
United States (279) · Canada (40) · China (33) · Germany (20) · Spain (16) · Turkey (Türkiye) (16) · Denmark (14) · Mexico (14) · India (10) · South Korea (10) · Taiwan (10) · Poland (9) · United Kingdom (9) · Egypt (8) · France (8)
David JA Jenkins, MD, PhD, DSc (7) · John L Sievenpiper, MD, PhD (7) · Russell J de Souza, ScD, RD (6) · Cyril WC Kendall, PhD (4) · Adrian Vella, MD (3) · Fumiko Higashikawa, PhD (3) · John L Sievenpiper, MD,PhD,FRCPC (3) · Philip Kern, MD (3) · Abigail Gamble, PhD, MS (2) · Anna M Gorczyca, PhD (2) · David Crowley, MD (2) · David G Marrero, Ph.D. (2) · David S Black, PhD MPH (2) · Emilia Papakonstantinou, PhD (2)
PMID 31301210, PMID 33436401, PMID 34131047, PMID 34135015, PMID 36938582, PMID 29941497, PMID 29941498, PMID 31178433, PMID 34131048, PMID 34274407, PMID 35894078, PMID 37625586, PMID 10480510, PMID 10857969, PMID 11832527, PMID 14578255, PMID 1574446, PMID 1578097, PMID 15823385, PMID 16644654, PMID 17315136, PMID 18312806, PMID 19092550, PMID 19490820, PMID 19833304, PMID 20395228, PMID 20529243, PMID 20561944, PMID 20833991, PMID 21272692, PMID 21593290, PMID 21788628, PMID 22024084, PMID 22253696, PMID 22269066, PMID 22331380, PMID 22351714, PMID 22354959, PMID 22358823, PMID 22446171, PMID 22457397, PMID 22610853, PMID 22723585, PMID 22773702, PMID 22930403, PMID 23204150, PMID 23436087, PMID 23455686, PMID 23469940, PMID 23498294
2023 (3), P50MD017344 (3), 2015 (2), OT2HL158287 (2), P30DK116074 (2), P50MD017338 (2), U01DK094406 (2), 1IK2CX002225-01A1 (1), 1OT2HL156812-01 (1), 2014 (1), 2016 (1), 2019 (1), 2025 (1), 3OT2OD035880-01S2 (1), 5UH3DK109543-05 (1)