32 completed, 10 unknown, 5 recruiting, 3 not yet recruiting. 52 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 52 | Completed 32, Unknown 10, Recruiting 5, Not yet recruiting 3, Withdrawn 2 |
| Phase 2 | 7 | Completed 7 |
Follow Postpartum Hemorrhage: new trials by email Literature Review of Postpartum Hemorrhage trials Research Report on Postpartum Hemorrhage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity Aspirin, Low-molecular-weight heparin - Venous Thromboembolism, Postpartum Period | Phase 3 | Recruiting | University of Calgary | 8805 | 2026-06-04 | 2026-07-27 |
| Investigating the Efficacy of Tranexamic Acid as a Prophylactic Agent in Reducing Postpartum Hemorrhage Among Patients Undergoing Cesarean Section in SQUH tranexamic acid (1 g diluted in 100 mL of 0.9% saline, Normal (0.9%) saline - Post Partum Haemorrhage | Phase 3 | Not yet recruiting | Sultan Qaboos University | 88 | 2026-05-01 | 2026-04-01 |
| EVE TRIAL , ALMA SYSTAM Alma System - Postpartum Haemorrhage (PPH), PPH | Phase 3 | Recruiting | ResQ Medical Ltd | 50 | 2026-01-11 | 2026-03-30 |
| Double Simultaneous Uterotonic Agents Versus Single Agent Regimen to Prevent Early Postpartum Hemorrhage Sublingual Misoprostol, IV Oxytocin - Postpartum Hemorrhage | Phase 3 | Recruiting | Stony Brook University | 1358 | 2025-01-27 | 2025-05-04 |
| Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage During Cesarean Section Misoprostol - Postpartum Hemorrhage | Phase 3 | Not yet recruiting | Assiut University | 400 | 2025-01-01 | 2025-01-09 |
| Prophylactic Amnioinfusion for Prevention of Postpartum Hemorrhage Saline delivered using an intrauterine pressure catheter (IUPC) - Postpartum Hemorrhage | Phase 3 | Not yet recruiting | The University of Texas Health Science Center, Houston | 700 | 2024-11-11 | 2024-11-18 |
| Comparing Intramyometrial Tranexamic Acid and Oxytocin for Blood Loss in Cesarean Section Tranexamic acid injection, Oxytocin - Cesarean Section Complications, Tranexamic Acid | Phase 3 | Unknown | Cairo University | 150 | 2024-10-01 | 2024-09-05 |
| Tranexamic Acid to Prevent Heavy Bleeding After Childbirth in Women At Higher Risk Tranexamic acid, Placebo - Postpartum Hemorrhage | Phase 3 | Recruiting | London School of Hygiene and Tropical Medicine | 30000 | 2024-04-22 | 2025-03-11 |
| Tranexamic Acid for the Prevention of Postpartum Hemorrhage in Pregnant Women With Placenta Previa Tranexamic acid, 0.9% sodium chloride - Hemorrhage, Postpartum, Placenta Previa | Phase 3 | Completed | Guangzhou Medical University | 1732 | 2023-07-12 | 2025-03-27 |
| Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery Calcium chloride, Saline placebo - Uterine Atony, Uterine Atony With Hemorrhage | Phase 3 | Completed | Stanford University | 120 | 2022-04-04 | 2024-06-11 |
| Prevent Postpartum Hemorrhage in Women With Von Willebrand Disease: The VWD-WOMAN Trial Recombinant Von Willebrand factor, Tranexamic Acid Injection [Cyklokapron] - Von Willebrand Diseases, Postpartum Hemorrhage | Phase 3 | Completed | Nicoletta C Machin | 20 | 2021-06-04 | 2025-10-31 |
| The Efficacy of Tranexamic Acid in Preventing Postpartum Haemorrhage After Caesarean Section Tranexamic acid injection, Normal saline placebo - Postpartum Hemorrhage | Phase 3 | Completed | University of Zimbabwe | 1226 | 2021-03-23 | 2023-03-20 |
| Sublingual vs Intrauterine MISOPROSTOL Plus Oxytocin Infusion for Prevention of Post-cesarean Hemorrhage in High Risk Pregnant Women: A Double-blind Placebo RCT sublingual Misoprostol, Intrauterine Misoprostol - To Compare Efficacy Intrauterine vs Sublingual MISOPROSTOL in Addition to Oxytocin in Reducing Blood Loss of Post-cesarean Section in High Risk Women | Phase 3 | Completed | Department of Medical Services Ministry of Public Health of Thailand | 135 | 2020-10-30 | 2021-09-13 |
| TRAnexamic Acid for Preventing Blood Loss Following a Cesarean Delivery in Women With Placenta pREVIA Tranexamic Acid / Sodium chloride - Postpartum Hemorrhage | Phase 3 | Recruiting | University Hospital, Bordeaux | 1380 | 2020-08-07 | 2025-02-10 |
| Tranexamic Acid in the Prevention of Postpartum Hemorrhage in Elective Caesarean Section Tranexamic acid, Normal saline - Postpartum Hemorrhage, Tranexamic Acid | Phase 3 | Completed | KK Women's and Children's Hospital | 200 | 2020-06-23 | 2022-11-09 |
| World Maternal Antifibrinolytic Trial_2 Tranexamic Acid, Placebo - Intrapartum - Moderate and Severe Anaemia | Phase 3 | Completed | London School of Hygiene and Tropical Medicine | 15068 | 2019-08-24 | 2024-01-10 |
| Tranexamic Acid for Prevention of Hemorrhage in Cesarean Delivery Tranexamic Acid, Placebo - Post Partum Hemorrhage, Fibrinolysis; Hemorrhage | Phase 2 / Phase 3 | Completed | University of Texas Southwestern Medical Center | 110 | 2019-06-17 | 2021-01-19 |
| Tranexamic Acid for Prevention of Postpartum Haemorrhage: a Dose-finding Study Tranexamic Acid - Post Partum Hemorrhage | Phase 3 | Completed | Mount Sinai Hospital, Canada | 24 | 2018-07-11 | 2021-09-23 |
| Efficacy of Tranexamic Acid in Preventing Postpartum Haemorrhage After Elective Caesarean Section Tranexamic Acid, Oxytocin - Post Partum Hemorrhage | Phase 3 | Completed | University of Zimbabwe | 506 | 2018-04-08 | 2022-06-01 |
| TRAnexamic Acid for Preventing Postpartum Hemorrhage Following a Cesarean Delivery Tranexamic Acid Injectable Solution, Sodium Chloride 0.9% - Postpartum Hemorrhage | Phase 3 | Completed | University Hospital, Bordeaux | 4574 | 2018-03-03 | 2026-05-12 |
Showing 20 of 52. Sign in to see all of them.
Hemorrhage (4) · Placenta Previa (3) · Pre-Eclampsia (2) · Uterine Inertia (2) · Anemia (1) · Familial Primary Pulmonary Hypertension (1) · Hyperthermia (1) · Pain (1) · Pulmonary Embolism (1) · Thrombophilia (1) · Venous Thromboembolism (1) · Venous Thrombosis (1) · von Willebrand Diseases (1)
Female Urogenital Diseases and Pregnancy Complications (52) · Obstetric Labor Complications (52) · Pathologic Processes (52) · Pathological Conditions, Signs and Symptoms (52) · Pregnancy Complications (52) · Puerperal Disorders (52) · Urogenital Diseases (52) · Uterine Hemorrhage (52) · Hemorrhage (48) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Placenta Diseases (3) · Dystocia (2) · Hypertension, Pregnancy-Induced (2) · Lung Diseases (2)
Tranexamic Acid (18) · Oxytocin (17) · Misoprostol (11) · Sodium Chloride (9) · carbetocin (6) · Saline Solution (3) · Ergonovine (2) · iron isomaltoside 1000 (2) · Aspirin (1) · Calcium Chloride (1) · Control Groups (1) · Dalteparin (1) · Enoxaparin (1) · Erythrocyte Transfusion (1) · Fibrinogen (1)
Ain Shams University (4) · Cairo University (4) · London School of Hygiene and Tropical Medicine (3) · Assiut University (2) · Azienda U.S.L. 1 di Massa e Carrara (2) · Gynuity Health Projects (2) · Pharmacosmos A/S (2) · Stanford University (2) · University Hospital, Bordeaux (2) · University of Zimbabwe (2) · Yariv yogev (2) · Benha University (1) · Copenhagen University Hospital at Herlev (1) · Department of Medical Services Ministry of Public Health of Thailand (1) · Dr Meng-Li Lee (1)
Egypt (11) · United States (7) · Denmark (4) · France (4) · Canada (2) · Israel (2) · Nigeria (2) · Tanzania (2) · Zimbabwe (2) · Argentina (1) · Belgium (1) · China (1) · India (1) · Ireland (1) · Italy (1)
Yariv Yogev, professor (2) · AbdelGany M Hassan (1) · Ahmed N Afifi, MD (1) · Ahmed N Shaker, MD (1) · Alexander J Butwick, F.R.C.A. (1) · Alicia V Aleman, MD (1) · Amgad E. Abou-Gamrah, Ass.Prof. (1) · Amon Agaba, PhD (1) · Amy Brenner (1) · Anne J. Wikkelsoe, MD (1) · Antonio Ragusa, Dr (1) · Arash Afshari, MD (1) · Bellington Vwalika (1) · Beverly Winikoff, MD, MPH (1)
PMID 33232518, PMID 39162220, PMID 11207490, PMID 17567419, PMID 22805300, PMID 25369200, PMID 25586727, PMID 25588587, PMID 27188698, PMID 27350226, PMID 28317031, PMID 28413832, PMID 28456509, PMID 29558233, PMID 29743045, PMID 29879947, PMID 29945633, PMID 30134136, PMID 30322584, PMID 30514326, PMID 30594227, PMID 30606246, PMID 31962259, PMID 32005192, PMID 32492040, PMID 33169839, PMID 33913639, PMID 35038612, PMID 35303924, PMID 37106343, PMID 37664793, PMID 37690946, PMID 37917943, PMID 38044460, PMID 38873634, PMID 39461792, PMID 40448004, PMID 40902088, PMID 41624591, PMID 42128454
2009 (1), 2014 (1), 2017 (1), D43TW005492 (1), D43TW009343 (1)