14 unknown, 7 completed, 6 recruiting, 5 not yet recruiting. 38 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 38 | Unknown 14, Completed 7, Recruiting 6, Not yet recruiting 5, Terminated 5, Active not recruiting 1 |
Follow Pleural Effusion, Malignant: new trials by email Literature Review of Pleural Effusion, Malignant trials Research Report on Pleural Effusion, Malignant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Feasibility of Medical Thoracoscopy Using Single-use Flexible Bronchoscope Versus SemiRigid Pleuroscope in Pleural Effusion Single-Use Flexible Bronchoscope, Semi-Rigid Pleuroscope - Malignant Pleural Effusions (Mpe), Medical Thoracoscopy | Not applicable | Recruiting | National University of Malaysia | 36 | 2026-08-20 | 2026-09-11 |
| Xuan Yin Ning Plus Bevacizumab for Malignant Pleural Effusion Treatment with Xuanyin Ning Formula combined with intrapleural injection of bevacizumab via chest tube drainage, Placebo granules plus chest tube drainage and intrapleural bevacizumab injection - Malignant Pleural Effusions (Mpe) | Not applicable | Not yet recruiting | Shanghai Chest Hospital | 308 | 2026-06-01 | 2026-07-01 |
| Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis Pleurodesis, pleurodesis - Pneumothorax Spontaneous Primary, Pneumothorax Spontaneous Secondary | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 160 | 2026-02-01 | 2026-01-06 |
| Pleurodesis in Small-bore Chest Tube 14 Fr chest tube, 12 Fr chest tube, 8 Fr chest tube - Pleural Effusion, Malignant | Not applicable | Not yet recruiting | The University of Hong Kong | 60 | 2026-02-01 | 2025-12-24 |
| Effectiveness of Intercostal Tube Drainage Vs Pigtail Catheter Drainage Vs Ultrasound-Guided Aspiration in Management of Massive Malignant Pleural Effusion intercostal tube drainage, big tail catheter drainage, ultrasound-guided aspiration - Malignant Pleural Effusion | Not applicable | Not yet recruiting | Assiut University | 66 | 2025-06-01 | 2025-05-09 |
| Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound side to side and front to back rotation 30 minutes each - Effect of Patient Rotation on Pleurodesis Success and Patient Comfort, Malignant Pleural Effusion | Not applicable | Recruiting | Ain Shams University | 30 | 2025-05-01 | 2025-08-29 |
| ARMSTRONG - Air entRainMent vS sTandard tReatment in nOn-expandable luNG Air Entrainment - intentional introduction of the atmospheric air into the pleural space. - Non-expandable Lung, Trapped Lung | Not applicable | Recruiting | Cambridge University Hospitals NHS Foundation Trust | 41 | 2025-04-14 | 2025-05-07 |
| Pleural Bleomycin vs Mechanical Abrasion in Malignant Pleural Effusion Group 1 (mechanical pleurodesis), Group 2 chemical pleurodesis by bleomycin) - Malignant Pleural Effusion | Not applicable | Not yet recruiting | Assiut University | 70 | 2024-12-10 | 2024-11-15 |
| The ACES Study for Aseptic Pleural Effusion Automatic Continuous Effusion Shunt implantation - Pleural Effusion | Not applicable | Active not recruiting | Pleural Dynamics, Inc. | 25 | 2024-05-12 | 2025-08-11 |
| Feasibility of Ambulatory Talc. Pleurodesis ambulatory chest drain and talc pleurodesis - Malignant Pleural Effusion, Malignancy | Not applicable | Recruiting | David Rollins | 15 | 2024-01-10 | 2024-11-12 |
| Impact of Pleural Manometry on the Assessment and Treatment of Malignant Pleural Effusion: A Pilot Clinical Trial Pleural manometry - Malignant Pleural Effusions (Mpe) | Not applicable | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 55 | 2023-07-28 | 2026-10-16 |
| First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis. Local Anesthesia Thoracoscopy, Pleuroscopy with Rigid Thoracoscope and Forceps biopsies - Suspected Malignant Lung Neoplasm, Pleural Effusion | Not applicable | Recruiting | National and Kapodistrian University of Athens | 100 | 2023-05-23 | 2025-04-27 |
| Clinical Study on Intraluminal Injection of FOLactis FOLactis - Solid Tumor, Immune Response | Not applicable | Unknown | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 40 | 2023-05-01 | 2024-07-22 |
| Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE) VATS-Surgical pleurodesis, Tube Drainage - Malignant Pleural Effusion, Thoracic Cancer | Not applicable | Unknown | Assiut University | 60 | 2023-04-01 | 2023-05-24 |
| Efficacy and Safety Study of Medical Thoracoscope Cryotherapy Combined Standard First-line Treatment of Advanced Non-small Cell Lung Cancer and Malignant Pleural Effusion Medical thoracoscopic cryotherapy combined with standard first-line therapy for advanced non-cell lung cancer, Sequential intrathoracic injection of cisplatin/erythromycin combined with standard first-line therapy for advanced non-cell lung cancer, Standard first-line therapy for advanced non-cell lung cancer without intrathoracic treatment - Non Small Cell Lung Cancer | Not applicable | Unknown | Qianfoshan Hospital | 141 | 2022-04-06 | 2023-11-18 |
| Oncodrivers in Malignant Pleural Effusions Associated With Non-small Cell Lung Cancer: A Prospective Study. meassurement of PD-L1, ALK, EGFR - Malignant Pleural Effusion, Non-small Cell Lung Cancer | Not applicable | Recruiting | Naestved Hospital | 100 | 2021-03-15 | 2026-06-24 |
| Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion Seldinger chest drain insertion - Pleural Effusion, Malignant, Lung Cancer Stage IV | Not applicable | Terminated | The University of Hong Kong | 52 | 2020-12-01 | 2025-03-28 |
| Use of Guidance Videos to Increase Engagement and Decrease Anxiety in Patients Undergoing Pleural Tap Personalized training video - Pleural Effusion, Pleural Effusion, Malignant | Not applicable | Unknown | GistMed Ltd. | 100 | 2020-02-16 | 2020-02-18 |
| A Randomised Study Evaluating Diagnostics of Pleural Effusion Among Patients Suspect of Cancer. Local anesthetic thoracoscopy, US-guided pleural biopsy - Pleural Effusion, Malignant, Pleural Effusion | Not applicable | Terminated | Naestved Hospital | 4 | 2019-12-20 | 2020-09-28 |
| Ultrasound-guided Biopsy of the Pleura as a Supplement to Extraction of Fluid in Patients With One-sided Fluid in the Pleura ultrasound-guided pleural biopsy, Thoracentesis - Malignant Pleural Effusion, Exudative Pleural Effusion | Not applicable | Terminated | Naestved Hospital | 5 | 2019-11-11 | 2020-09-25 |
Showing 20 of 38. Sign in to see all of them.
Pleural Effusion (10) · Lung Neoplasms (4) · Myeloproliferative Disorder, Chronic, with Eosinophilia (4) · Carcinoma, Non-Small-Cell Lung (3) · Neoplasms (3) · Pleural Diseases (2) · Pneumothorax (2) · Breast Neoplasms (1) · Mesothelioma (1) · Mesothelioma, Malignant (1) · Neoplasm Metastasis (1) · Respiration Disorders (1) · Tuberculosis (1)
Neoplasms by Site (38) · Pleural Neoplasms (38) · Respiratory Tract Diseases (38) · Respiratory Tract Neoplasms (38) · Thoracic Neoplasms (38) · Pleural Diseases (36) · Neoplasms (35) · Pleural Effusion (28) · Lung Diseases (7) · Bronchial Neoplasms (3) · Carcinoma, Bronchogenic (3) · Lung Neoplasms (3) · Actinomycetales Infections (1) · Adenoma (1) · Bacterial Infections (1)
Pleurodesis (3) · Chest Tubes (2) · Therapeutics (2) · Acetaminophen (1) · Cisplatin (1) · Coal Tar (1) · Doxycycline (1) · Endoscopic Ultrasound-Guided Fine Needle Aspiration (1) · Fentanyl (1) · Genes, fms (1) · Povidone-Iodine (1) · Thoracentesis (1) · Thoracoscopy (1)
Assiut University (3) · Naestved Hospital (3) · Post Graduate Institute of Medical Education and Research, Chandigarh (3) · C. R. Bard (2) · The University of Hong Kong (2) · Ain Shams University (1) · Cambridge University Hospitals NHS Foundation Trust (1) · David Rollins (1) · Fox Chase Cancer Center (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · GistMed Ltd. (1) · Guy's and St Thomas' NHS Foundation Trust (1) · NHS Greater Glasgow and Clyde (1) · National Taiwan University Hospital (1) · National University Hospital, Singapore (1)
United Kingdom (6) · United States (6) · China (5) · Denmark (3) · Egypt (3) · India (3) · Australia (1) · Canada (1) · Greece (1) · Hong Kong (1) · Israel (1) · Malaysia (1) · Pakistan (1) · Singapore (1) · Spain (1)
Chao-Chi Ho, PhD (1) · Dheeraj Gupta, MD, DM, FCCP (1) · Fabien Moldanado, MD, MSc (1) · Fei Ma, MD (1) · Grigorios Stratakos, Professor (1) · Hongbiao Wang, Master (1) · Hossein Borghaei (1) · Joseph B Shrager, MD (1) · Kayvan Amjadi, MD (1) · Kevin C Ma (1) · Kevin Conroy, MBBS, FRCP (1) · King Pui Florence Chan, MD (1) · Mei Sze Macy Lui, MD (1) · Mohamed Faisal Abdul Hamid, MBBS(IIUM) (1) · Mohamed M Abd ElHady, Professor (1)
PMID 11451810, PMID 20696688, PMID 25377015, PMID 25874452, PMID 26720026, PMID 28344925, PMID 29862030, PMID 31374208, PMID 33538338, PMID 35363591, PMID 37428348, PMID 38243259, PMID 42669653, PMID 591413, PMID 6857580
P30CA006927 (1)