2 recruiting. 2 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 2 | Recruiting 2 |
Follow Pineoblastoma: new trials by email Literature Review of Pineoblastoma trials Research Report on Pineoblastoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies. SGT-53, hypofractionated radiotherapy with immunotherapy, Nivolumab - CNS Malignancies, Medulloblastoma Recurrent | Early Phase 1 | Recruiting | Children's National Research Institute | 18 | 2025-12-16 | 2026-04-29 |
| Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation Cytarabine IT, hydrocortisone, Cisplatin - CNS Embryonal Tumor, CNS, Medulloblastoma | Early Phase 1 | Recruiting | C17 Council | 15 | 2025-09-23 | 2026-07-14 |
Pinealoma (2) · Central Nervous System Neoplasms (1) · Medulloblastoma (1) · Neoplasms, Germ Cell and Embryonal (1) · Neuroblastoma (1) · Neuroectodermal Tumors, Primitive (1) · Pyloric Stenosis, Hypertrophic (1) · Rhabdoid Tumor (1)
Brain Diseases (2) · Brain Neoplasms (2) · Central Nervous System Diseases (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Neoplasms by Site (2) · Neoplasms, Glandular and Epithelial (2) · Neoplasms, Nerve Tissue (2) · Neoplasms, Neuroepithelial (2) · Nervous System Diseases (2) · Nervous System Neoplasms (2) · Neuroectodermal Tumors (2) · Central Nervous System Neoplasms (1) · Digestive System Diseases (1) · Gastric Outlet Obstruction (1)
Carboplatin (1) · Celecoxib (1) · Cisplatin (1) · Cyclophosphamide (1) · Etoposide (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Hydrocortisone (1) · Immunotherapy (1) · Isotretinoin (1) · Mesna (1) · Nivolumab (1) · Tamoxifen (1) · Temozolomide (1) · Thiotepa (1)
C17 Council (1) · Children's National Research Institute (1)
Canada (1) · United States (1)
Annie Huang (1) · Lucie Lafay-Cousin (1) · Sylvia Cheng (1)