42 completed, 13 recruiting, 9 unknown, 4 not yet recruiting. 61 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3, 1 Phase 4.
Follow Physiological Stress: new trials by email Literature Review of Physiological Stress trials Research Report on Physiological Stress
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Electric Fans in Children During Heat Waves Simulated exposure to indoor overheating without fans, Simulated exposure to indoor overheating with fans - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 60 | 2026-10-02 | 2026-10-07 |
| Progressive Heat Exposure and Physiological Strain Constant Heat Exposure, Progressively Increasing Heat Exposure - Body Temperature Changes, Heat Stress | Not applicable | Not yet recruiting | University of Ottawa | 14 | 2026-10-01 | 2026-09-29 |
| Lower Body Negative Pressure to Validate Physiological Monitors Lower Body Negative Pressure with Noninvasive Physiological Monitoring - Physiological Stress | Not applicable | Recruiting | Mayo Clinic | 50 | 2026-09-30 | 2026-09-24 |
| Effect of White Noise on Salivary Cortisol and Vital Signs During Gastroscopy White Noise - Procedural Anxiety, Physiological Stress | Not applicable | Not yet recruiting | Yuzuncu Yil University | 100 | 2026-09-27 | 2026-09-02 |
| Multidisciplinary Health Monitoring for Esports Players Multidisciplinary Preventive Exercise Program - Musculoskeletal Pain, Sedentary Behavior | Not applicable | Not yet recruiting | Yeditepe University | 30 | 2026-09-01 | 2026-06-24 |
| Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults Cranberry juice, Placebo juice - Stress Response, Mental Stress | Not applicable | Recruiting | University of Florida | 84 | 2026-08-01 | 2026-06-30 |
| Exercise Intensity and Heat Responses in Children and Youth Low-Intensity Exercise in the Heat, Moderate-Intensity Exercise in the Heat, Vigorous-Intensity Exercise in the Heat - Body Temperature Changes, Heat Stress | Not applicable | Enrolling by invitation | University of Ottawa | 12 | 2026-07-21 | 2026-08-24 |
| Ambient Temperature and Thermoregulation During Exercise in Children and Youth Exercise at 22°C, Exercise at 26°C, Exercise at 31°C - Body Temperature Changes, Heat Stress | Not applicable | Recruiting | University of Ottawa | 12 | 2026-07-19 | 2026-08-24 |
| Consecutive Occupational Heat Exposure With and Without Overnight Cooling Simulated occupational heat exposure with recovery at recommended indoor temperature limit, Simulated occupational heat exposure with recovery in an overheated indoor environment - Body Temperature Changes, Heat Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2026-06-24 | 2026-10-05 |
| Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological Strain Simulated Occupational heat exposure under normoxic conditions, Simulated Occupational heat exposure under hypoxic conditions - Body Temperature Changes, Heat Stress | Not applicable | Recruiting | University of Ottawa | 20 | 2026-06-17 | 2026-07-14 |
| Effects of Feel Free® Classic Tonic on Stress and Pharmacokinetics in Healthy Adults Placebo, Kava and Kratom Herbal Supplement - Anxiety, Physiological Stress | Not applicable | Recruiting | Botanic Tonics, LLC | 165 | 2026-03-07 | 2026-05-01 |
| Impact of Indoor Overheating on Physiological Strain in Children Simulated exposure to indoor overheating - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2025-11-08 | 2026-04-23 |
| Heat Stress in Individuals With Schizophrenia Simulated exposure to indoor overheating - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2025-11-08 | 2026-04-23 |
| Suitability of a 26 °C Indoor Environment for Mitigating Heat Strain in Young Adults Simulated indoor temperature upper limit - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2025-11-07 | 2026-06-16 |
| Suitability of the 26 °C Indoor Temperature Upper Limit for Older Adults: Impacts of Clothing and Daily Activity Simulated indoor temperature upper limit - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2025-09-23 | 2026-04-23 |
| Addressing Weight Bias Internalization to Improve Adolescent Weight Management Outcomes: Randomized Pilot Trial Behavioral Weight Management, Weight Bias Internalization - Weight, Body Weight | Not applicable | Active not recruiting | The Miriam Hospital | 64 | 2025-03-25 | 2026-07-21 |
| Influence of Indoor Humidity on Physiological Strain in Older Adults During a Simulated Heat Wave Simulated indoor overheating - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2025-03-14 | 2025-06-15 |
| Parental Stress and Attachment in Preterm Infants hair cortisol, salivary cortisol, salivary Oxytocin - Premature Birth, Psychological Stress | Not yet recruiting | Cardenal Herrera University | 60 | 2025-02-01 | 2025-02-07 | |
| The Effects of Mannose Supplementation on Glycosylation and Protein Levels in Human Sera Mannose - Physiological Stress | Not applicable | Completed | University of Texas Southwestern Medical Center | 6 | 2024-10-29 | 2025-02-27 |
| The Effect of Music Listening on Nursing Students Sedative Music, Stimulative Music - Stress, Physiological Stress | Not applicable | Completed | University of Miami | 34 | 2024-10-21 | 2025-04-18 |
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Heat Stress Disorders (16) · Stress, Psychological (16) · Motor Activity (12) · Hyperthermia (9) · Body Temperature Changes (5) · Anxiety Disorders (4) · Depression (4) · Feeding Behavior (4) · Fatigue (3) · Fractures, Stress (3) · Occupational Stress (3) · Premature Birth (3) · Acute Pain (2) · Hypoxia (2) · Multitasking Behavior (2)
Behavior (32) · Pathological Conditions, Signs and Symptoms (26) · Signs and Symptoms (24) · Behavioral Symptoms (21) · Wounds and Injuries (19) · Mental Disorders (10) · Neurologic Manifestations (8) · Body Temperature Changes (6) · Nervous System Diseases (6) · Pathologic Processes (5) · Urogenital Diseases (5) · Behavior, Animal (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Occupational Diseases (4) · Pregnancy Complications (4)
Exercise (2) · Milk (2) · Yogurt (2) · Atomoxetine Hydrochloride (1) · Blood Pressure Monitors (1) · Blood Specimen Collection (1) · Dexmedetomidine (1) · Electrocardiography (1) · Facilitated Tucking (1) · Galvanic Skin Response (1) · Health (1) · Hydrocortisone (1) · Manipulation, Osteopathic (1) · Mannose (1) · Mindfulness (1)
University of Ottawa (15) · University of Illinois at Urbana-Champaign (4) · Sheba Medical Center (3) · Texas State University (3) · University of Florida (2) · Alfredo Anderson Teixeira de Araujo (1) · Amsterdam UMC, location VUmc (1) · Bastyr University (1) · Botanic Tonics, LLC (1) · Brian Gehlbach (1) · Brigham and Women's Hospital (1) · Cardenal Herrera University (1) · Centre Hospitalier Régional Metz-Thionville (1) · Come Collaboration (1) · Fazer Group (1)
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Glen P Kenny, PhD (7) · Ofir Frenkel, M.D (3) · Ronald J Sigal, MD, MPH (2) · Anne Marie Chomat, MD, PhD, MPH (1) · Arja Uusitalo, MD (1) · Breno S Santana, MsC (1) · Brian K Gehlbach, MD (1) · Christopher Pelt, M.D. (1) · Clemens Acker, Dr. (1) · David Borsook, MD, PhD (1) · Dominique de Quervain, Prof. Dr. (1) · Frank Euteneuer, Prof. Dr. (1) · Gail K Adler, MD, PhD (1) · Glen Kenny, PhD (1)
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K02DA021304 (1), R01HL143792 (1), R21MD013650 (1), U01HL069294 (1), U24CA076518 (1)