18 completed, 4 terminated, 4 unknown, 1 active not recruiting. 28 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 28 | Completed 18, Terminated 4, Unknown 4, Active not recruiting 1, Recruiting 1 |
Follow PCOS: new trials by email Literature Review of PCOS trials Research Report on PCOS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Liraglutide Treatment in Obese Infertile PCOS Women Liraglutide and metformin, Metformin - PCOS, Obesity | Phase 4 | Recruiting | Peking University Third Hospital | 890 | 2025-05-22 | 2025-05-29 |
| Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation Letrozole, Clomiphene Citrate - Polycystic Ovary Syndrome, PCOS | Phase 4 | Active not recruiting | Rachel Mejia | 190 | 2020-10-26 | 2025-04-15 |
| The Effects of Semaglutide on Taste, Tongue Tissue Transcriptome, Gastric Emptying and Central Neural Response in Women With PCOS and Obesity Semaglutide, Placebo - PCOS, Semaglutide | Phase 4 | Completed | University Medical Centre Ljubljana | 30 | 2019-11-02 | 2023-09-08 |
| Vitamin D Supplementation in PCOS Patients Vitamin D, Placebo Oral Tablet - PCOS | Phase 4 | Completed | Tanta University | 170 | 2019-04-01 | 2022-05-05 |
| The Gut Microbiome in Women With Polycystic Ovary Syndrome dietary advice plus myo-inositol and folic acid, dietary advice plus Liraglutide Pen Injector - PCOS, Obesity | Phase 4 | Completed | Universitaire Ziekenhuizen KU Leuven | 21 | 2019-02-28 | 2020-11-04 |
| Vitamin D for Polycystic Ovary Syndrome Clomiphene Resistant Women Vit D, Metformin, Clomiphene - PCOS, Vitamin D Deficiency | Phase 4 | Completed | Ain Shams University | 120 | 2018-04-01 | 2019-07-08 |
| Research of Intensive Metabolic Intervention Before Pregnancy in PCOS Acarbose 100 MG, Exenatide, Orlistat - PCOS, Impaired Glucose Tolerance | Phase 4 | Unknown | RenJi Hospital | 160 | 2018-01-01 | 2017-12-26 |
| Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial Metformin, Vitamin D - PCOS, Depression | Phase 4 | Terminated | University of California, San Francisco | 5 | 2017-12-12 | 2021-02-09 |
| OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS Ethinyl Estradiol-cyprosterone acetate, Metformin Hydrochloride - PCOS | Phase 4 | Completed | S.C.B. Medical College and Hospital | 101 | 2017-08-01 | 2018-03-20 |
| Effect of Dietary Modifacation on Microbiota in Overweight and Obese Polycystic Ovary Syndrome Patients Dietary and life style modification and probiotic Sanprobi Super Formula, Placebo - PCOS | Phase 4 | Unknown | Poznan University of Medical Sciences | 80 | 2017-05-20 | 2017-10-30 |
| Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type 2 Diabetes in Metformin Intolerant Obese Women With Polycystic Ovary Syndrome Sitagliptin, Lifestyle intervention - PCOS | Phase 4 | Completed | University Medical Centre Ljubljana | 30 | 2016-08-01 | 2017-04-20 |
| Clomiphene Citrate Versus Tamoxifen for Ovulation Induction in PCOs Clomiphene citrate, Tamoxifen Placebo, Tamoxifen - PCOS | Phase 4 | Completed | Ain Shams University | 600 | 2015-06-01 | 2016-05-17 |
| Short Term Weight Loss With Liraglutide and Metformin in Infertile Obese PCOS Patients Metformin, Liraglutide + metformin - Obesity, PCOS | Phase 4 | Completed | University Medical Centre Ljubljana | 35 | 2014-04-01 | 2017-01-27 |
| PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary Syndrome metformin, liraglutide, roflumilast - PCOS, Obesity | Phase 4 | Completed | University Medical Centre Ljubljana | 45 | 2014-03-01 | 2014-07-10 |
| Liraglutide as Add on Therapy on Metformin in Women With Polycystic Ovary Syndrome Metformin, Glucophage tablets and Victoza - PCOS, Obesity | Phase 4 | Completed | University Medical Centre Ljubljana | 40 | 2014-01-01 | 2015-06-26 |
| Role of Myo-inositol and D-chiro Inositol on the Ovaric and Metabolic Functions Myo-inositol + D-chiro-inositol + Folic acid, Folic acid - PCOS | Phase 4 | Completed | Lo.Li.Pharma s.r.l | 46 | 2014-01-01 | 2017-02-14 |
| PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome metformin, metformin and roflumilast - PCOS, Obesity | Phase 4 | Completed | University Medical Centre Ljubljana | 36 | 2013-09-01 | 2014-01-22 |
| Metformin in Step-down Regimen Versus Conventional Low Dose Step-up Protocol in Patients With PCOS Undergoing IVF Metformin, gonadotropins in step-down regimen, Placebo, gonadotropins in step-up regimen - Infertility, PCOS | Phase 4 | Unknown | University of Modena and Reggio Emilia | 120 | 2013-06-01 | 2013-07-12 |
| PCOS, Therapy and Markers of Cardiovascular Risk oral metformin, oral contraceptive - PCOS | Phase 4 | Unknown | Medical University of Gdansk | 50 | 2012-04-01 | 2013-03-01 |
| Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin metformin, liraglutide, metformin and liraglutide - PCOS, Obesity | Phase 4 | Completed | University Medical Centre Ljubljana | 36 | 2011-11-01 | 2013-07-30 |
Showing 20 of 28. Sign in to see all of them.
Obesity (9) · Infertility (6) · Polycystic Ovary Syndrome (6) · Insulin Resistance (4) · Vitamin D Deficiency (2) · Anxiety Disorders (1) · Depression (1) · Dysgeusia (1) · Glucose Intolerance (1) · Hyperandrogenism (1) · Metabolic Diseases (1) · Metabolic Syndrome (1) · Mood Disorders (1)
Nutritional and Metabolic Diseases (16) · Nutrition Disorders (11) · Genital Diseases (10) · Pathological Conditions, Signs and Symptoms (10) · Signs and Symptoms (10) · Urogenital Diseases (10) · Body Weight (9) · Overnutrition (9) · Overweight (9) · Adnexal Diseases (6) · Cysts (6) · Endocrine System Diseases (6) · Female Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6) · Genital Diseases, Female (6)
Metformin (15) · Liraglutide (6) · Solutions (4) · Clomiphene (3) · Folic Acid (3) · Injections (3) · Inositol (3) · Roflumilast (2) · Vitamin D (2) · Acarbose (1) · Cholecalciferol (1) · Contraceptives, Oral (1) · Diet (1) · Exenatide (1) · Gonadotropins (1)
University Medical Centre Ljubljana (8) · AGUNCO Obstetrics and Gynecology Centre (2) · Ain Shams University (2) · Virginia Commonwealth University (2) · AZ Jan Palfijn Gent (1) · Lo.Li.Pharma s.r.l (1) · Medical University of Gdansk (1) · Peking University Third Hospital (1) · Poznan University of Medical Sciences (1) · Rachel Mejia (1) · RenJi Hospital (1) · S.C.B. Medical College and Hospital (1) · Tanta University (1) · Universitaire Ziekenhuizen KU Leuven (1) · University Magna Graecia (1)
Slovenia (7) · Italy (5) · United States (4) · Egypt (3) · Belgium (2) · China (2) · Poland (2) · India (1)
Andrej Janez, MD, PhD (3) · Stefano Palomba, MD (2) · Abdel-Latif G. El-Kholy, MD (1) · Ahmed MN Hashaad, Professor (1) · Alaa M Ismail, M D (1) · Andrej Janez, MD PhD (1) · Diana N. Kolta, MB BCh (1) · Eda Vrtacnik Bokal, professor (1) · Fulvio Zullo, MD (1) · Gasser M. El-Bishry, FRCOG (1) · Heather Huddleston, MD (1) · Leo Dunn, MD (1) · Mohamed S. Sweed, MD (1) · Paulina A Essah, M.D. (1) · Priyadarshini Tripathy, MD (1)
PMID 21733508, PMID 21917254, PMID 24554512, PMID 25330463, PMID 26032655, PMID 34050763, PMID 34281590, PMID 39636391
U54HD034449 (1)