3 completed, 1 not yet recruiting. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 3, Not yet recruiting 1 |
| Phase 1 | 1 | Not yet recruiting 1 |
Follow Parasitemia: new trials by email Literature Review of Parasitemia trials Research Report on Parasitemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Transmission-Blocking Vaccine Pvs230D1-EPA/Matrix-M in Healthy Malaria-Naive Adults Using a Plasmodium Vivax Controlled Human Malaria Infection and Transmission Model Plasmodium vivax Challenge Agent Derived from PvHMB-CCE001, Pvs230D1-EPA/Matrix-M - Healthy Volunteers, Malaria | Phase 1 / Phase 2 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 220 | 2026-11-18 | 2026-11-13 |
| Aggressive Antipyretics for Fever Reduction in CNS Malaria Acetaminophen, Ibuprofen, placebo for acetaminophen - Malaria, Seizures | Phase 2 | Completed | University of Rochester | 256 | 2019-01-07 | 2024-03-05 |
| Cardiac Safety of Dihydroartemisinin-Piperaquine Amongst Pregnant Women in Tanzania sulfadoxine-pyrimethamine (SP), dihydroartemisinin-piperaquine (DHA-PQP) - Malaria, Pregnancy Malaria | Phase 2 | Completed | London School of Hygiene and Tropical Medicine | 201 | 2016-09-01 | 2021-02-02 |
| A Study to Assess Efficacy, Safety of KAE609 in Adult Patients With Acute Malaria Mono-infection KAE609 - Cure Rate | Phase 2 | Completed | Novartis Pharmaceuticals | 11 | 2013-07-01 | 2015-09-10 |
Malaria (3) · Cardiotoxicity (1) · Coma (1) · Fever (1) · Hyperthermia (1) · Malaria, Vivax (1) · Seizures (1)
Infections (4) · Inflammation (4) · Parasitic Diseases (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Sepsis (4) · Systemic Inflammatory Response Syndrome (4) · Mosquito-Borne Diseases (3) · Protozoan Infections (3) · Vector Borne Diseases (3) · Wounds and Injuries (2) · Body Temperature Changes (1) · Cardiovascular Diseases (1) · Chemically-Induced Disorders (1) · Consciousness Disorders (1)
Acetaminophen (1) · Ibuprofen (1) · NITD 609 (1) · fanasil, pyrimethamine drug combination (1)
London School of Hygiene and Tropical Medicine (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Novartis Pharmaceuticals (1) · University of Rochester (1)
Malawi (1) · Tanzania (1) · Thailand (1) · United States (1) · Vietnam (1) · Zambia (1)
Gretchen L Birbeck, MD (1) · Jacklin Mosha, MBBS, MSc, PhD (1) · R. Matthew Chico, MPH, PhD (1) · Shanan R Immel, M.D. (1)
PMID 36316704, PMID 38640099, PMID 38857015
R01NS102176 (1)