518 completed, 111 unknown, 65 recruiting, 43 active not recruiting. 614 Not applicable, 42 Phase 2, 37 Phase 1, 12 Phase 3, 12 Phase 4.
Follow Overweight and Obesity: new trials by email Literature Review of Overweight and Obesity trials Research Report on Overweight and Obesity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cardiometabolic Effects of the Recommended Daily Pecan Intake Dose Pecan, Control - Nutrition, Healthy, Dyslipidemia | Not applicable | Not yet recruiting | University of Georgia | 90 | 2027-03-01 | 2026-08-11 |
| EMBodied psychOsocial Impacts of Weight Stigma During Pregnancy (EMBODY): A Prospective Cohort Study Weight Stigma, Pregnancy Outcomes | Not yet recruiting | Monash University | 800 | 2027-02-01 | 2026-10-16 | |
| Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or Obesity Tirzepatide - Type 1 Diabetes Mellitus, Overweight and Obesity | Phase 2 | Not yet recruiting | Royal North Shore Hospital | 40 | 2026-12-01 | 2025-07-29 |
| Cognitive and Behavioral Approaches to Reduce Binge Eating and Excess Weight in Adolescents (Online) Cognitive-Behavioral Therapy for Adolescent Binge Eating, Lifestyle Behavioral Obesity Intervention, Active Control - Binge Eating, Overweight and Obesity | Not applicable | Not yet recruiting | Indiana University | 159 | 2026-11-01 | 2026-10-05 |
| SHIFT-TB: Nutrition Intervention and Evaluation Community-Based Nutrition Intervention - Underweight, Overweight and Obesity | Not applicable | Not yet recruiting | National University of Singapore | 700 | 2026-10-01 | 2026-09-23 |
| A Study to Investigate the Safety and Efficacy of TE-8105 in Overweight or Obesity Participants TE-8105 MAD Cohort 1, TE-8105 MAD Cohort 2, TE-8105 MAD Cohort 3 - Overweight and Obesity | Phase 2 | Not yet recruiting | Immunwork, Inc. | 204 | 2026-10-01 | 2026-10-05 |
| Weight Loss Goals and Satisfaction Survey Personalized 3D Body Visualization - Overweight and Obesity | Not yet recruiting | Pennington Biomedical Research Center | 250 | 2026-08-01 | 2026-04-21 | |
| A Phase 1, Double-blind, Randomized Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Single Dose and Multiple Doses of CG-0416 in Healthy Participants. CG-0416 - Overweight and Obesity | Phase 1 | Not yet recruiting | HongKong Curegene Innovation Co., Limited | 64 | 2026-07-01 | 2026-07-24 |
| A Study of DA-302168S in Participants With Overweight/Obesity DA-302168S, Placebo - Overweight and Obesity | Phase 3 | Recruiting | Chendu DIAO Pharmaceutical Group CO., LTD. | 840 | 2026-06-19 | 2026-08-06 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS9531 Injection in Adolescents With Obesity HRS9531 injection；Placebo - Overweight and Obesity | Phase 1 | Active not recruiting | Fujian Shengdi Pharmaceutical Co., Ltd. | 48 | 2026-06-12 | 2026-09-28 |
| Validity and Reliability of Mixed Reality-Based Performance Tests in Overweight and Obese Adults Mixed Reality-Based Functional Mobility and Performance Assessment - Overweight and Obesity | Recruiting | Selcuk University | 119 | 2026-06-10 | 2026-06-17 | |
| CHOICE to AVOID or RESIST AVOID, RESIST - Overweight and Obesity | Not applicable | Recruiting | Cedars-Sinai Medical Center | 60 | 2026-06-01 | 2026-09-22 |
| AI-Driven Metabolic Cohort in Overweight/Obese Chinese Adults Overweight and Obesity, Diabetes Mellitus, Type 2 | Not yet recruiting | Zhujiang Hospital | 2800 | 2026-05-01 | 2026-05-13 | |
| Genetic Markers Associated With Capsaicinoid Supplementation Effects in Overweight and Obesity Capsipro supplementation, Corn starch placebo - Overweight and Obesity | Not applicable | Active not recruiting | Universidad Autonoma de Baja California | 100 | 2026-04-22 | 2026-05-22 |
| ABUNDANCE of A NATURAL ODOUR in HUMAN CEREBROSPINAL FLUID AFTER OLFACTORY EXPOSURE - the OLFO-Brain Study Inhalation - Natural Odour, Inhalation - Placebo - Overweight and Obesity | Early Phase 1 | Recruiting | University Hospital, Basel, Switzerland | 32 | 2026-04-14 | 2026-05-04 |
| Prognostic Value of SII and SIRI in Obesity-Related Metabolic Complications Nutritional counselling - Overweight and Obesity, Inflammation | Recruiting | University of Rijeka | 200 | 2026-04-01 | 2026-05-07 | |
| Health Outcomes in C-Section Infants With Fecal Microbiota Transplantation Donor-derived fecal microbiota transplantation - Fecal Microbiota Transplantation, Cesarean Section | Not applicable | Recruiting | Oulu University Hospital | 460 | 2026-03-31 | 2026-07-21 |
| Online Dietary Weight Loss Program for Arab Adults: A Randomized Controlled Trial Online Lifestyle and Dietary Program, Usual Dietary Care - Overweight and Obesity | Not applicable | Enrolling by invitation | Asma Yahya | 68 | 2026-03-09 | 2026-04-09 |
| Understanding the Health Effect of a Bioactive Peptide From Egg: A Pilot Study Egg White Powder - High Blood Sugar, High Blood Pressure | Phase 1 | Recruiting | University of Alberta | 28 | 2026-02-25 | 2026-03-13 |
| GRK-Biased Activation Via β2-Adrenergic Receptors in Human Skeletal Muscle ATR-258 - Overweight and Obesity | Phase 2 | Active not recruiting | Morten Hostrup, PhD | 13 | 2026-02-19 | 2026-10-14 |
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Obesity (790) · Overweight (790) · Weight Loss (95) · Motor Activity (93) · Diabetes Mellitus, Type 2 (52) · Hypertension (50) · Metabolic Syndrome (46) · Prediabetic State (40) · Insulin Resistance (35) · Diabetes Mellitus (34) · Feeding Behavior (28) · Dyslipidemias (26) · Cardiovascular Diseases (25) · Pediatric Obesity (23) · Sedentary Behavior (23)
Pathological Conditions, Signs and Symptoms (790) · Signs and Symptoms (789) · Nutritional and Metabolic Diseases (788) · Overnutrition (787) · Nutrition Disorders (786) · Body Weight (771) · Metabolic Diseases (196) · Glucose Metabolism Disorders (179) · Behavior (168) · Endocrine System Diseases (126) · Body Weight Changes (104) · Diabetes Mellitus (81) · Hyperinsulinism (76) · Vascular Diseases (56) · Cardiovascular Diseases (47)
Exercise (34) · Diet (19) · High-Intensity Interval Training (11) · Methods (10) · Cognitive Behavioral Therapy (6) · Control Groups (6) · Diet Therapy (6) · Behavior Therapy (5) · Diet, Ketogenic (5) · Blood Glucose Self-Monitoring (4) · Glucose (4) · Nutrition Assessment (4) · Probiotics (4) · Resistance Training (4) · Standard of Care (4)
Maastricht University Medical Center (15) · University of Colorado, Denver (14) · Johns Hopkins University (13) · University of North Carolina, Chapel Hill (12) · The Miriam Hospital (10) · University of California, San Diego (9) · Massachusetts General Hospital (8) · University of South Carolina (7) · Clinica Universidad de Navarra, Universidad de Navarra (6) · Columbia University (6) · Ohio University (6) · Chendu DIAO Pharmaceutical Group CO., LTD. (5) · Pennington Biomedical Research Center (5) · University of Aarhus (5) · University of Alabama at Birmingham (5)
United States (311) · China (42) · Spain (34) · United Kingdom (30) · Canada (28) · Denmark (28) · Germany (22) · Italy (20) · Netherlands (20) · Mexico (18) · Australia (14) · France (14) · Brazil (12) · Greece (11) · Norway (11)
David S Drozek, DO (5) · Elsie Taveras, MD, MPH (4) · Deborah F Tate, PhD (3) · Dejan Reljic, Dr. (3) · Joshua R Cook, MD, PhD (3) · Yurdaguel Zopf, Prof. (3) · Bohdan Luhovyy, PhD (2) · Catherine L Davis, PhD (2) · Claire Ing, DrPH (2) · Danielle Ostendorf, PhD (2) · Dr Alexandra M Johnstone, PhD (2) · Elsie Taveras, MD (2) · Emilia Papakonstantinou, PhD (2)
PMID 38375882, PMID 26641646, PMID 2748771, PMID 28993707, PMID 33367782, PMID 33512717, PMID 34986271, PMID 37625586, PMID 7080884, PMID 10500011, PMID 10511607, PMID 10534586, PMID 10741889, PMID 10811152, PMID 10875899, PMID 11191537, PMID 11444448, PMID 11459880, PMID 11724655, PMID 12150599, PMID 12452227, PMID 12796570, PMID 12841551, PMID 12900694, PMID 15049746, PMID 15204662, PMID 15361314, PMID 15549021, PMID 15703762, PMID 15821725, PMID 16036192, PMID 16158151, PMID 16318465, PMID 16371744, PMID 16377046, PMID 16380542, PMID 16565998, PMID 16608613, PMID 16703434, PMID 16848714, PMID 16861326, PMID 16895997, PMID 16925881, PMID 16945915, PMID 17060764, PMID 17105655, PMID 17116424, PMID 17167471, PMID 17183312, PMID 17217636
R01HL168858 (3), K01HL161417 (2), R01HL087923 (2), U01CA150387 (2), 1DP3DK113358-01 (1), 2015 (1), 2018 (1), 2019 (1), 2023 (1), 5UL1TR001857-04 (1), K01DK107791 (1), K01DK113048 (1), K12DK133995 (1), K23DK114480 (1), K23DK115820 (1)