7 unknown, 5 recruiting, 3 completed. 8 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 3, Unknown 3, Recruiting 2 |
| Phase 2 | 2 | Recruiting 2 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Overlap Syndrome: new trials by email Literature Review of Overlap Syndrome trials Research Report on Overlap Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| LYell SYndrome MEsenchymal Stromal Cells Treatment Adipose derived stromal cells intravenously injected - Epidermal Necrolysis, Lyell Syndrome | Phase 1 / Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 15 | 2024-04-15 | 2025-08-01 |
| The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome) bi-level positive pressure non invasive ventilation, Oxygen gas - Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease | Phase 2 | Recruiting | University of California, San Diego | 240 | 2024-02-13 | 2026-06-03 |
| Impact of Continuous Positive Airway Pressure on the Occurrence of Acute Exacerbations of COPD in Patients With COPD-OSA Overlap Syndrome (CO-OS) continuous positive airway pressure treatment - Sleep Apnea, COPD Exacerbation | Not applicable | Recruiting | University Hospital, Angers | 500 | 2024-01-09 | 2025-04-13 |
| Biomarkers of Dementia in Chronic Sleep and Breathing Disorders High density electroencephalogram (HdEEG), Functional near infrared spectroscopy (fNIRS), Magnetic resonance imaging (MRI) - COPD, Overlap Syndrome | Unknown | Woolcock Institute of Medical Research | 104 | 2023-12-01 | 2024-04-22 | |
| Evaluation of High Velocity Nasal Insufflation in Management of Respiratory Failure in Patients With Overlap Syndrome High Velocity Nasal Insufflation, Non-invasive mechanical ventilation - Overlap Syndrome, Obesity Hypoventilation Syndrome | Not applicable | Unknown | Assiut University | 50 | 2023-03-01 | 2022-07-20 |
| Irritable Bowel Syndrome Overlaping Celiac Disease Celiac Disease, Irritable Bowel Syndrome | Unknown | Centre of Postgraduate Medical Education | 500 | 2023-01-22 | 2023-02-23 | |
| Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome) Positive airway pressure, Conservative care (control arm) - Sleep Apnea Syndrome, Obstructive Sleep Apnea | Not applicable | Recruiting | VA Office of Research and Development | 668 | 2020-12-01 | 2026-06-05 |
| Continuous Positive Pressure Versus Bi-level in Overlap Syndrome Bi-level positive airway pressure with ventilatory support, continuous positive airway pressure without ventilatory support - Overlap Syndrome, Nocturnal Hypoventilation | Not applicable | Unknown | Hospital Sao Joao | 70 | 2019-01-01 | 2018-12-06 |
| Canadian Network for Autoimmune Liver Disease Observational; no intervention - Primary Bilary Cirrhosis (PBC), Autoimmune Hepatitis | Recruiting | University Health Network, Toronto | 2500 | 2018-02-07 | 2021-06-07 | |
| "Overlap Syndrome and PSC: Evaluating Role of Gut Microflora and Its Identification With Antibiotics in Children" Metronidazole - Primary Sclerosing Cholangitis, Autoimmune Hepatitis | Not applicable | Completed | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 15 | 2016-01-01 | 2022-08-05 |
| Systematic Approach for the Diagnosis and Treatment of Obstructive Lung Diseases LABA + LAMA, ICS, LABA + LAMA + ICS - Chronic Obstructive Pulmonary Disease, Asthma | Unknown | KU Leuven | 180 | 2015-07-01 | 2020-04-08 | |
| Initiation of Non- Invasive Ventilation at Home Versus Hospital Among Patients With Overlap Syndrome IniVAH, IniVAD - Overlap Syndrome | Not applicable | Unknown | IP Santé Domicile | 80 | 2015-02-01 | 2015-08-06 |
| Right Ventricular Hemodynamics Using Cardiac MRI in Patients COPD and OSA Bi-level positive airway pressure (BPAP), Nocturnal oxygen - Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease | Not applicable | Completed | University of California, San Diego | 23 | 2014-09-01 | 2020-07-28 |
| Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome Bipap procedure - Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea | Phase 3 | Unknown | United States Air Force | 150 | 2011-12-01 | 2011-09-01 |
| Auto-trilevel Ventilator for Patients With Overlap Syndrome BiPAP ventilation, auto-trilevel ventilation - Overlap Syndrome | Not applicable | Completed | Nanjing Medical University | 17 | 2011-08-01 | 2012-11-27 |
Pulmonary Disease, Chronic Obstructive (8) · Sleep Apnea, Obstructive (4) · Hepatitis, Autoimmune (2) · Sleep Apnea Syndromes (2) · Apnea (1) · Asthma (1) · Celiac Disease (1) · Cholangitis, Sclerosing (1) · Irritable Bowel Syndrome (1) · Nervous System Diseases (1) · Obesity Hypoventilation Syndrome (1) · Respiration Disorders (1) · Respiratory Tract Diseases (1) · Signs and Symptoms, Respiratory (1) · Sleepiness (1)
Chronic Disease (8) · Disease Attributes (8) · Lung Diseases (8) · Lung Diseases, Obstructive (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Respiratory Tract Diseases (8) · Dyssomnias (6) · Sleep Disorders, Intrinsic (6) · Sleep Wake Disorders (6) · Apnea (5) · Nervous System Diseases (5) · Respiration Disorders (5) · Immune System Diseases (4) · Sleep Apnea Syndromes (4)
Noninvasive Ventilation (2) · Blood Specimen Collection (1) · Continuous Positive Airway Pressure (1) · Magnetic Resonance Imaging (1) · Mental Status and Dementia Tests (1) · Metronidazole (1) · Polysomnography (1) · Respiratory Function Tests (1) · Surveys and Questionnaires (1) · laminin A (1) · nitrox (1)
University of California, San Diego (2) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Centre of Postgraduate Medical Education (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Hospital Sao Joao (1) · IP Santé Domicile (1) · KU Leuven (1) · Nanjing Medical University (1) · United States Air Force (1) · University Health Network, Toronto (1) · University Hospital, Angers (1) · VA Office of Research and Development (1) · Woolcock Institute of Medical Research (1)
United States (4) · France (3) · Belgium (2) · Australia (1) · Canada (1) · China (1) · Egypt (1) · Poland (1)
Andrew Mason, MD (1) · Ashraf Z El-Abdeen Mohammed, Professor (1) · Atul Malhotra, MD (1) · Bettina Hansen, PhD (1) · Etienne Sokal, MD, PhD (1) · Lamiaa H Shaaban, Professor (1) · Marie Pia D'orthor, MD (1) · Robert L Owens, MD (1) · Safia Maaradji-Gati, MD (1) · Saskia Oro, PhD (1) · Susmita Chowdhuri, MD MS (1) · Waleed G Elddin Khaleel, Lecturer (1) · Wim Janssens, MD (1)