3 completed, 3 recruiting, 2 not yet recruiting, 1 active not recruiting. 6 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Recruiting 2, Active not recruiting 1, Completed 1, Not yet recruiting 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Osteosarcoma Metastatic: new trials by email Literature Review of Osteosarcoma Metastatic trials Research Report on Osteosarcoma Metastatic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fight Osteosarcoma Through European Research Evolving Study Platform From Diagnosis to Relapse Experimental group : Cabometyx ® 40mg/m2/day (Max: 60mg/day) , Treatment schedule : Daily**, day 1-28 during 4 weeks (ie. 1 cycle) during 12 cycles - Osteosarcoma, Pediatric Osteosarcoma | Phase 3 | Recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 530 | 2026-10-07 | 2026-10-26 |
| A Study to Assess Safety and Efficacy of SOT106 in Patients With LRRC15-positive Advanced Unresectable or Metastatic Osteosarcoma or Soft Tissue Sarcoma SOT106 - Osteosarcoma Metastatic, Soft Tissue Sarcoma (STS) | Phase 1 / Phase 2 | Not yet recruiting | SOTIO Biotech a.s. | 70 | 2026-09-30 | 2026-09-03 |
| Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma Liposomal Irinotecan, Apatinib in arm1 - Osteosarcoma, Osteosarcoma Metastatic | Phase 1 / Phase 2 | Recruiting | Peking University People's Hospital | 56 | 2026-03-05 | 2026-03-18 |
| A Look Back at How Well Interventional Treatments Work for Bronchopleural Fistulas in Patients With Lung Metastases From Osteosarcoma Interventional therapy - Osteosarcoma Metastatic | Not yet recruiting | Ruijin Hospital | 28 | 2025-05-01 | 2025-04-15 | |
| XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue Sarcoma Biospecimen Collection, Computed Tomography, Echocardiography - Metastatic Leiomyosarcoma, Unresectable Leiomyosarcoma | Phase 2 | Recruiting | Northwestern University | 73 | 2024-09-19 | 2026-10-13 |
| SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma Regorafenib 40 MG, Regorafenib 20MG, Nivolumab - Osteosarcoma, Osteosarcoma in Children | Phase 2 | Active not recruiting | Sarcoma Alliance for Research through Collaboration | 48 | 2021-06-04 | 2025-10-31 |
| Study of Effectiveness of GEMDOX in Relapsed Osteosarcoma observation - Osteosarcoma Recurrent, Osteosarcoma Metastatic | Completed | Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna | 33 | 2020-04-24 | 2021-11-26 | |
| Osteosarcoma With Resectable Pulmonary Metastasis: A Retrospective Study resection group, radiotherapy group - Osteosarcoma Metastatic, Pulmonary Disease | Completed | Peking University People's Hospital | 127 | 2020-01-01 | 2020-12-04 | |
| BIO-11006 for Osteosarcoma and Ewing's Sarcoma Lung Metastases Chemotherapy (gemcitabine & docetaxel) plus BIO-11006 - Osteosarcoma Metastatic, Ewing's Sarcoma Metastatic | Phase 2 | Withdrawn | Nicklaus Children's Hospital f/k/a Miami Children's Hospital | 2019-10-04 | 2024-11-08 | |
| Inhalation SLIT Cisplatin (Liposomal) for the Treatment of Osteosarcoma Metastatic to the Lung Cisplatin liposomal - Osteosarcoma Metastatic | Phase 1 / Phase 2 | Completed | Insmed Incorporated | 19 | 2005-01-12 | 2017-08-01 |
Osteosarcoma (7) · Bone Neoplasms (2) · Sarcoma (2) · Leiomyosarcoma (1) · Lung Diseases (1) · Neoplasm Metastasis (1) · Recurrence (1) · Sarcoma, Ewing (1) · Sarcoma, Synovial (1)
Neoplasms (8) · Neoplasms by Histologic Type (8) · Neoplasms, Connective and Soft Tissue (8) · Neoplasms, Bone Tissue (7) · Neoplasms, Connective Tissue (7) · Sarcoma (6) · Bone Diseases (2) · Musculoskeletal Diseases (2) · Neoplasms by Site (2) · Disease Attributes (1) · Neoplasms, Muscle Tissue (1) · Neoplastic Processes (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Respiratory Tract Diseases (1)
26S proteasome non-ATPase regulatory subunit 13 (1) · Docetaxel (1) · Drug Therapy (1) · Gemcitabine (1) · MAX protein, human (1) · Nivolumab (1) · Observation (1) · SPI-77, liposomal (1) · Specimen Handling (1) · apatinib (1) · irinotecan sucrosofate (1) · regorafenib (1)
Peking University People's Hospital (2) · Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · Insmed Incorporated (1) · Nicklaus Children's Hospital f/k/a Miami Children's Hospital (1) · Northwestern University (1) · Ruijin Hospital (1) · SOTIO Biotech a.s. (1) · Sarcoma Alliance for Research through Collaboration (1)
United States (4) · China (2) · Italy (2) · Denmark (1) · Finland (1) · France (1) · Moldova (1) · Netherlands (1) · Poland (1) · Spain (1) · Sweden (1)
Franca Fagioli, MD (1) · Guillermo De Angulo, MD (1) · Pedro Hermida de Viveiros, MD (1) · Renu Gupta, MD (1) · Richard Gorlick, MD (1) · Silvia Stacchiotti, M.D. (1) · Wei Guo, M.D. (1)
2023 (1), P30CA060553 (1)