16 completed, 2 terminated, 1 recruiting, 1 withdrawn. 6 Phase 3, 5 Phase 4, 4 Phase 1, 3 Phase 2, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 5, Terminated 1 |
| Phase 4 | 5 | Completed 3, Recruiting 1, Withdrawn 1 |
| Phase 1 | 4 | Completed 4 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Not applicable | 2 | Completed 2 |
Follow salmon calcitonin: new trials by email Literature Review of salmon calcitonin trials Research Report on salmon calcitonin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Use of Intranasal Calcitonin to Improve Pain and Activity in Elderly Pelvic Ring Injuries Miacalcin Calcitonin Salmon Nasal Spray - Pelvic Ring Fractures | Phase 4 | Completed | University of Missouri-Columbia | 21 | 2019-07-01 | 2024-06-11 |
| Calcitonin Pre-treatment to Improve SPECT-CT Sensitivity Calcitonin - Primary Hyperparathyroidism, Hypercalcemia | Phase 4 | Recruiting | Joseph Sferra | 37 | 2019-05-29 | 2024-09-19 |
| Hypothyroidism Treated With Calcitonin Calcitonin - Hypothyroidism | Phase 4 | Completed | University of Maryland, Baltimore | 11 | 2018-06-18 | 2022-02-21 |
| Calcitonin for Treating X-linked Hypophosphatemia nasal salmon calcitonin, Saline Nasal Spray Placebo - Hypophosphatemic Rickets, X Linked Dominant | Not applicable | Completed | Yale University | 21 | 2011-03-01 | 2017-05-31 |
| A Study Comparing Oral Calcitonin to Nasal Spray Calcitonin in Postmenopausal Osteoporotic Women Oral Calcitonin Tablets, Intranasal Calcitonin, Placebo tablets and placebo intranasal spray - Osteoporosis, Postmenopausal | Phase 3 | Completed | Tarsa Therapeutics, Inc. | 565 | 2009-06-01 | 2013-11-19 |
| A Study of Oral Calcitonin Given at Night to Healthy Postmenopausal Women Oral rsCT tablet, Oral Placebo Tablet, Fortical (rsCT) nasal spray - Phase 1 Pharmacodynamic Study | Phase 2 | Completed | Tarsa Therapeutics, Inc. | 12 | 2008-12-01 | 2014-06-09 |
| Calcitonin in the Treatment of Fibromyalgia salmon calcitonin, intranasal saline solution plus glycerol - Fibromyalgia | Phase 4 | Withdrawn | Unidad de Investigacion en Enfermedades Cronico-Degenerativas | 2008-10-01 | 2015-12-04 | |
| Efficacy and Safety of Oral Salmon Calcitonin in Patients With Knee Osteoarthritis (OA 2 Study) Oral Salmon Calcitonin, Oral Salmon Calcitonin (Placebo) - Osteoarthritis | Phase 3 | Terminated | Nordic Bioscience A/S | 1030 | 2008-06-01 | 2019-04-24 |
| A Dose Selection Study of Oral Recombinant Salmon Calcitonin (rsCT) in Normal, Healthy, Postmenopausal Women Recombinant Salmon Calcitonin (rsCT), Oral Tablet, Nasal Spray - Osteoporosis | Phase 2 | Completed | Tarsa Therapeutics, Inc. | 24 | 2008-02-01 | 2012-02-01 |
| Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus sildenafil, calcitonin, hydrochlorothiazide/amiloride - Nephrogenic Diabetes Insipidus | Not applicable | Completed | University of Colorado, Denver | 4 | 2007-05-01 | 2018-02-12 |
| Bone Microstructure in Nasal Salmon Calcitonin Treated Postmenopausal Women Salmon calcitonin - Postmenopause | Phase 3 | Completed | Rene Rizzoli | 90 | 2007-01-01 | 2011-12-23 |
| SMC021A - Absorption, Efficacy and Tolerance in Patients With Osteoarthritis. A Placebo-Controlled 14-Days Study Oral salmon calcitonin - Osteoarthritis | Phase 1 | Completed | Nordic Bioscience A/S | 2007-01-01 | 2007-06-14 | |
| A Study for Patients With Osteoporosis Teriparatide, Salmon Calcitonin - Osteoporosis | Phase 3 | Completed | Eli Lilly and Company | 364 | 2006-12-01 | 2009-10-28 |
| Effects of Water and Food Intake on the Pharmacokinetics and Pharmacodynamics of Oral Salmon Calcitonin in Healthy Postmenopausal Women Oral salmon calcitonin, salmon calcitonin nasal spray - Postmenopausal Osteoporosis | Phase 1 | Completed | Novartis | 56 | 2006-10-01 | 2007-05-28 |
| Pharmacokinetics and Pharmacodynamics Study of Oral Salmon Calcitonin in Healthy Postmenopausal Women Oral salmon calcitonin - Postmenopausal Osteoporosis | Phase 1 | Completed | Novartis | 86 | 2006-08-01 | 2006-12-13 |
| Pharmacokinetics/Pharmacodynamics of Oral Salmon Calcitonin in Patients With Osteoarthritis Oral salmon calcitonin, salmon calcitonin nasal spray - Osteoarthritis | Phase 1 | Completed | Nordic Bioscience A/S | 2005-10-01 | 2007-06-14 | |
| Comparison Medications in the Treatment of Postmenopausal Women With Osteoporosis teriparatide 20 micrograms/day subcutaneous, salmon calcitonin 100 IU/day subcutaneous - Osteoporosis, Postmenopausal | Phase 3 | Completed | Eli Lilly and Company | 70 | 2003-08-01 | 2007-10-12 |
| A Study of the Treatment of Postmenopausal Women With Osteoporosis teriparatide 20 micrograms/day subcutaneous, salmon calcitonin 100 IU/day subcutaneous - Osteoporosis, Post-Menopausal | Phase 3 | Completed | Eli Lilly and Company | 104 | 2003-06-01 | 2007-10-12 |
| Effects of Oral Salmon Calcitonin in Human Osteoarthritis oral salmon calcitonin - Osteoarthritis | Phase 2 | Terminated | Université Catholique de Louvain | 54 | 2002-09-01 | 2006-09-14 |
| Efficacy and Safety of Salmon Calcitonin Nasal Spray in Improving Muscle Strength and Reducing Pain After Forearm Fracture in Postmenopausal Women Salmon calcitonin - Forearm Fracture | Phase 4 | Completed | Novartis | 300 | 2002-03-01 | 2006-11-30 |
Osteoporosis, Postmenopausal (5) · Osteoarthritis (4) · Osteoporosis (4) · Diabetes Insipidus, Nephrogenic (1) · Familial Hypophosphatemic Rickets (1) · Fibromyalgia (1) · Hypercalcemia (1) · Hyperparathyroidism, Primary (1) · Hypothyroidism (1) · Pain (1) · Polyuria (1)
Eli Lilly and Company (3) · Nordic Bioscience A/S (3) · Novartis (3) · Tarsa Therapeutics, Inc. (3) · Joseph Sferra (1) · Rene Rizzoli (1) · Unidad de Investigacion en Enfermedades Cronico-Degenerativas (1) · University of Colorado, Denver (1) · University of Maryland, Baltimore (1) · University of Missouri-Columbia (1) · Université Catholique de Louvain (1) · Yale University (1)
United States (9) · Denmark (6) · Belgium (2) · China (2) · Poland (2) · United Kingdom (2) · Bulgaria (1) · Canada (1) · Czechia (1) · Germany (1) · Hong Kong (1) · Hungary (1) · Mexico (1) · Romania (1) · South Africa (1)
Bente J Riis, M.D. (2) · Thomas Legg, D.O. (2) · Bente Juel Riis, MD (1) · Brett Crist, MD (1) · Cesar R. Ramos-Remus, M.D., MSc (1) · Daniel H Manicourt, MD, PhD (1) · David Krause, M.D. (1) · Joseph Sferra, MD (1) · Karl L Insogna, MD (1) · Kashif Munir, M.D. (1) · Melissa A Cadnapaphornchai, MD (1)
PMID 18405390, PMID 19055791, PMID 19747581, PMID 20565725, PMID 20932224, PMID 22437792, PMID 25582279, PMID 29343266, PMID 31481084, PMID 32249039, PMID 41764561
2008 (1), R21AR061818 (1)