6 completed, 1 unknown, 1 withdrawn. 8 Phase 2, 3 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 6, Unknown 1, Withdrawn 1 |
| Phase 3 | 3 | Completed 2, Withdrawn 1 |
| Phase 1 | 2 | Completed 1, Unknown 1 |
Follow Osteoarthrosis: new trials by email Literature Review of Osteoarthrosis trials Research Report on Osteoarthrosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| E1K Intra Articular(IA) Treatment for Knee Osteoarthritis E1K 1,200 ㎍/joint, E1K 2,400 ㎍/joint, placebo - Osteoarthrosis | Phase 2 | Completed | Ensol Bioscience | 120 | 2022-06-13 | 2024-04-04 |
| Autologous Adipose-Derived Stromal Vascular Fraction Cells for Osteoarthritis Treatment Intra-articular auto-SVFs injection, Hyaluronic Acid - Osteoarthritis, Joint Disease | Phase 1 / Phase 2 | Completed | Russian Academy of Medical Sciences | 27 | 2016-03-01 | 2019-09-13 |
| Effect of Methylprednisolone on Orthostatic Intolerance and Heart Rate Variability in Hip-arthroplasty Patients Methylprednisolone, Isotonic Sodium Chloride - Osteoarthrosis | Phase 2 / Phase 3 | Completed | Copenhagen University Hospital, Rigshospitalet | 64 | 2015-09-01 | 2017-01-18 |
| Effect of Methylprednisolone on Immune Signaling in Hip-arthroplasty Patients Methylprednisolone, Isotonic Sodium Chloride - Osteoarthrosis | Phase 2 / Phase 3 | Completed | Copenhagen University Hospital, Rigshospitalet | 64 | 2015-09-01 | 2017-01-18 |
| Intraoperative Liposomal Bupivacaine Injection in Primary Total Knee Arthroplasty Bupivacaine Liposome Injection, Indwelling femoral nerve block - Osteoarthritis, Osteoarthritis, Knee | Phase 2 / Phase 3 | Withdrawn | United States Naval Medical Center, San Diego | 2015-03-01 | 2017-03-10 | |
| Topical and Intravenous Administration of TXA Are Equally Effective in DAA THA 1.5g intravenous Exacyl, 3.0g intra-articular Exacyl - Osteoarthrosis | Phase 2 | Completed | Ziekenhuis Oost-Limburg | 120 | 2014-07-01 | 2016-02-05 |
| Evaluation of Two Types of PRP in Knee Osteoarthritis Platelets Rich Plasma, Leucocyte - Platelets Rich Plasma, Hialuronic Acid - Osteoarthrosis | Phase 1 / Phase 2 | Unknown | University of Campinas, Brazil | 120 | 2013-11-01 | 2016-10-04 |
| A Safety, Tolerability and Pharmacokinetic Dose Escalation Study of HC-ER in Patients With Osteoarthritis Pain 10 mg of Hydrocodone Bitartrate Extended Release (HC-ER), 20 mg of Hydrocodone Bitartrate Extended Release (HC-ER) - Osteoarthrosis | Phase 2 | Completed | Zogenix, Inc. | 37 | 2002-09-01 | 2022-11-10 |
Osteoarthritis (8) · Osteoarthritis, Knee (2) · Joint Diseases (1) · Orthostatic Intolerance (1)
Arthritis (8) · Musculoskeletal Diseases (8) · Rheumatic Diseases (8) · Joint Diseases (7) · Autonomic Nervous System Diseases (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Primary Dysautonomias (1) · Signs and Symptoms (1)
Methylprednisolone (2) · Methylprednisolone Hemisuccinate (2) · Sodium Chloride (2) · Hyaluronic Acid (1) · Hydrocodone (1) · Tranexamic Acid (1)
Copenhagen University Hospital, Rigshospitalet (2) · Ensol Bioscience (1) · Russian Academy of Medical Sciences (1) · United States Naval Medical Center, San Diego (1) · University of Campinas, Brazil (1) · Ziekenhuis Oost-Limburg (1) · Zogenix, Inc. (1)
Denmark (2) · Belgium (1) · Brazil (1) · Russia (1) · South Korea (1) · United States (1)
Viktoria Lindberg-Larsen, MD (2) · Alexander A Ostanin, MD, PhD (1) · Elena R Chernykh, MD, PhD (1) · Kristoff Corten, Prof. dr. (1) · Patrick B Morrissey, M.D. (1) · Young-Wan Moon, M.D., Ph.D. (1)
PMID 22174345, PMID 25253674, PMID 29573263, PMID 32152813, PMID 32719355
2015 (2)