16 completed, 3 unknown, 2 recruiting, 1 active not recruiting. 26 Phase 2, 2 Phase 1, 2 Phase 3.
Follow Oral Lichen Planus: new trials by email Literature Review of Oral Lichen Planus trials Research Report on Oral Lichen Planus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions 5-Amino Levulinic Acid - Oral Cancer, Oral Cavity Cancer | Phase 2 | Not yet recruiting | University of Massachusetts, Boston | 65 | 2026-09-01 | 2026-03-19 |
| Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus Topical Bromelain, 0.1% topical triamcinolone acetonide, Combination of Topical Bromelain and Triamcinolone Acetonide in Orabase - Oral Lichen Planus | Phase 2 | Recruiting | Cairo University | 42 | 2026-02-18 | 2026-06-09 |
| Thyme Honey for Management of Oral Lichen Planus thyme honey, Triamcinolone Acetonide - Oral Lichen Planus | Phase 1 / Phase 2 | Enrolling by invitation | British University In Egypt | 30 | 2024-10-12 | 2025-02-06 |
| Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus Clobetasol Patch, Clobetasol + Resveratrol Patch, Clobetasol in Orabase - Oral Lichen Planus, Oral Lichen Planus Related Stress | Phase 2 | Recruiting | University of Palermo | 45 | 2024-09-04 | 2025-08-03 |
| Evaluating LP-10 in Subjects With OLP LP-10 (Liposomal Tacrolimus) - Oral Lichen Planus | Phase 2 | Unknown | Lipella Pharmaceuticals, Inc. | 24 | 2024-07-01 | 2025-05-15 |
| Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study Baricitinib 4 milligram Oral Tablet - Lichen Planus, Oral, Lichen Planus, Mucosal | Phase 2 | Completed | University of North Carolina, Chapel Hill | 10 | 2024-03-13 | 2026-10-30 |
| A Comparison of Photodynamic Therapy and Topical Clobetasol in Treatment of Oral Lichen Planus: a Split-Mouth Randomised Controlled Study Photodynamic Therapy, Clobetasol - Oral Lichen Planus | Phase 2 | Completed | Wroclaw Medical University | 29 | 2023-06-01 | 2024-12-30 |
| Evaluation of Efficacy of Neem (Azadirachta Indica) Versus Triamcinolone Acetonide in the Treatment of Oral Lichen Planus. Neem gel, Triamcinolone Acetonide - Oral Lichen Planus | Phase 1 / Phase 2 | Completed | Goa Dental College | 60 | 2023-02-05 | 2025-09-03 |
| Dexamethasone Solution and Dexamethasone in Mucolox™ dexamethasone 0.5mg/5ml solution, dexamethasone 0.5mg/5ml solution in Mucolox™ - Oral Lichen Planus, Mucous Membrane Pemphigoid | Phase 2 | Completed | University of California, San Francisco | 29 | 2020-12-26 | 2023-12-15 |
| Efficacy of Topical Treatment With Clobetasol in Symptomatic Oral Lichen Planus. Clobetasol Propionate, Placebo/Klobetasol APL oral gel 0.025%, Placebo - Oral Lichen Planus | Phase 2 / Phase 3 | Active not recruiting | Malmö University | 90 | 2020-05-18 | 2024-12-04 |
| Evaluation of the Effectiveness of Photodynamic Therapy in the Treatment of Lesions of the Lichen Planus Type in the Oral Mucosa and Its Diagnostics With the Use of Autofluorescence, in Various Wavelength Ranges, in Combination With the Use of Texture Analysis and Fractal Dimension PDT Therapy, Triamcinolone (Substance) therapy side - Oral Lichen Planus | Phase 2 | Completed | Wroclaw Medical University | 30 | 2020-02-08 | 2021-08-05 |
| Apremilast - Oral Lichen Planus Trial Apremilast, Placebo - Oral Lichen Planus | Phase 2 | Withdrawn | Sunnybrook Health Sciences Centre | 2019-11-21 | 2020-06-25 | |
| Intra-oral Treatment of OLP With Rivelin®-CLO Patches Clobetasol Propionate - Oral Lichen Planus | Phase 2 | Completed | Dermtreat | 140 | 2018-06-28 | 2020-07-14 |
| Use of Topical NSAID to Reduce Pain in Oral Lichen Planus and Oral Lichenoid Lesions. Ibuprofen suspension 5mg/100ml, Placebos - Oral Lichen Planus, Oral Lichenoid Mucositis | Phase 2 / Phase 3 | Completed | University of Washington | 23 | 2018-04-29 | 2020-05-08 |
| Effect of Bifidobacterium Animalis Subsp. Lactis HN019 on Oral Lichen Planus Bifidobacterium animalis subsp. lactis HN019, Clobetasol propionate 0.05% - Oral Lichen Planus | Phase 2 | Completed | University of Sao Paulo | 22 | 2017-11-06 | 2020-03-27 |
| Topical Betamethasone and Clobetasol in Orabase in Oral Lichen Planus Betamethasone Dipropionate, Clobetasol Propionate - Oral Lichen Planus | Phase 2 | Unknown | Garlapati Komali | 30 | 2016-05-06 | 2018-03-14 |
| Comparison of Tacrolimus 0.1% and Clobetasol 0.05% in the Management of Symptomatic Oral Lichen Planus Tacrolimus 0.1%, Clobetasol 0.05% - Oral Lichen Planus | Phase 2 | Completed | University of Peradeniya | 68 | 2014-06-01 | 2016-04-20 |
| Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planus Licorice, Triamcinolone Acetonide - Oral Lichen Planus | Phase 2 | Completed | Isfahan University of Medical Sciences | 60 | 2014-01-01 | 2015-05-25 |
| The Efficacy of Omega-3 in Treatment of Atrophic/Erosive Lichen Planus Prednisone tablet 5mg, Omega-3 soft capsules 1000 mg - Oral Lichen Planus | Phase 2 | Completed | October 6 University | 30 | 2013-05-01 | 2015-04-28 |
| Topical "Non-Aromatic Very Rich in Steranes" (NAVS) Naphthalan for the Treatment of Oral Mucosal Diseases NAVS Naphthalan, 0.05% Betamethasone dipropionate - Oral Lichen Planus, Recurrent Aphthous Stomatitis | Phase 2 | Completed | Ivan Alajbeg | 57 | 2010-12-01 | 2016-09-30 |
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Lichen Planus, Oral (26) · Lichen Planus (2) · Bronchiolitis Obliterans Syndrome (1) · Carcinoma in Situ (1) · Leukoplakia, Oral (1) · Mouth Neoplasms (1) · Oral Ulcer (1) · Pemphigoid, Benign Mucous Membrane (1) · Pemphigus (1) · Squamous Cell Carcinoma of Head and Neck (1) · Stomatitis, Aphthous (1) · Torulopsis (1) · Ulcer (1)
Lichenoid Eruptions (26) · Mouth Diseases (26) · Skin Diseases (26) · Skin Diseases, Papulosquamous (26) · Skin and Connective Tissue Diseases (26) · Stomatognathic Diseases (26) · Lichen Planus (24) · Pathological Conditions, Signs and Symptoms (2) · Autoimmune Diseases (1) · Bronchial Diseases (1) · Bronchiolitis (1) · Bronchiolitis Obliterans (1) · Bronchitis (1) · Carcinoma (1) · Carcinoma, Squamous Cell (1)
Clobetasol (5) · Triamcinolone Acetonide (4) · Dexamethasone (2) · Diarylheptanoids (2) · Orabase (2) · Photochemotherapy (2) · Solutions (2) · Triamcinolone (2) · betamethasone-17,21-dipropionate (2) · Adrenal Cortex Hormones (1) · Aminolevulinic Acid (1) · Bromelains (1) · Doxycycline (1) · Gels (1) · Glycyrrhiza glabra extract (1)
Mashhad University of Medical Sciences (2) · University of California, San Francisco (2) · Wroclaw Medical University (2) · British University In Egypt (1) · Cairo University (1) · Dermtreat (1) · Garlapati Komali (1) · Goa Dental College (1) · Isfahan University of Medical Sciences (1) · Ivan Alajbeg (1) · Lipella Pharmaceuticals, Inc. (1) · Malmö University (1) · National Institute of Dental and Craniofacial Research (NIDCR) (1) · Nita Chainani Wu (1) · October 6 University (1)
United States (9) · Egypt (3) · India (3) · Canada (2) · Iran (2) · Poland (2) · Brazil (1) · Croatia (1) · Denmark (1) · Germany (1) · Ireland (1) · Italy (1) · Sweden (1) · United Kingdom (1)
Alessandro Villa, DDS, PhD, MPH (1) · Arash Mansourian, DDS,MS (1) · Christopher Hull, MD (1) · Donna Culton, MD, PhD (1) · Ellen E Monteiro, Student (1) · Enas Elgendy, ph.D (1) · Fatemeh Momen Heravi (1) · Gilberto A Silva, MS (1) · Hagen Klieb, HBSc, MSc, DMD, FRCD(C) (1) · Ivan Alajbeg, PhD (1) · Jonathan Celli, PhD (1) · Kleber Tanaka Suzuki, DDS (1)
PMID 18155609, PMID 21175873, PMID 21907450, PMID 33831097, PMID 37549933, PMID 41174333, PMID 42163196
U01CA279862 (1)