7 completed, 3 unknown, 2 not yet recruiting, 1 active not recruiting. 7 Not applicable, 2 Phase 4, 1 Early Phase 1, 1 Phase 1, 1 Phase 2.
Follow Opioids: new trials by email Literature Review of Opioids trials Research Report on Opioids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impacts of Opioids on Respiratory Drive During Sleep Morphine p.o., Placebo - Opioids, Obstructive Sleep Apnea (OSA) | Early Phase 1 | Not yet recruiting | Brigham and Women's Hospital | 26 | 2026-07-01 | 2026-01-29 |
| Bupivacaine Liposomes or Bupivacaine for CMB on Postoperative Analgesia in Laparoscopic Hepatobiliary Pancreatic Surgery Bupivacaine Liposomes(BL), Bupivacaine(B) - Bupivacaine, Ultrasound-Guided | Phase 4 | Recruiting | Huazhong University of Science and Technology | 60 | 2025-10-08 | 2026-07-06 |
| Acupuncture Versus Compound Diclofenac Sodium for Pain Relief in Non-Traumatic Acute Abdominal acupuncture, compound diclofenac sodium, acupuncture combined with compound diclofenac sodium - Acute Abdominal Pain, Acupuncture Therapy | Phase 1 / Phase 2 | Not yet recruiting | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | 176 | 2025-06-01 | 2025-05-21 |
| Transcutaneous Electrical Stimulation for Apnea Detected by Capnography transcutaneous electrical nerve stimulation (TENS) - Respiratory Depression, Opioids | Not applicable | Completed | University of Toronto | 60 | 2025-04-10 | 2026-06-11 |
| Machine-Learning Prediction and Reducing Overdoses With EHR Nudges EHR-Embedded Elevated-Risk Flag, EHR-Embedded Elevated-Risk Flag with Behavioral Nudges, Usual Care - Opioid Overdose, Opioid Use | Not applicable | Active not recruiting | University of Pittsburgh | 1350 | 2025-03-10 | 2026-10-06 |
| WorkWell - Preventing Prescription Opioid Misuse Among Employees Working in High Risk Industries WorkWell - Opioids | Not applicable | Completed | Prevention Strategies, LLC | 759 | 2024-08-07 | 2026-09-02 |
| The Attitudes and Beliefs of Hispanic/Latino Individuals Toward Prescription Opioids and Non-Medical Opioid Use Opioid Attitudes, Beliefs survey - Opioids | Withdrawn | M.D. Anderson Cancer Center | 2023-03-23 | 2024-08-02 | ||
| I-COPE Study: Opioid Use and Pain Management in Older Adults I-COPE - Chronic Pain, Opioids | Not applicable | Completed | University of Chicago | 20000 | 2021-06-03 | 2024-06-24 |
| The Comparative Efficacy and Safety of Two General Anesthesia Protocols Consisting of Fentanyl Plus Propofol Plus Rococuronium Plus Isoflurane Versus Ketamime Plus Magnesium Sulphate Plus Lidocaine Plus Clonidine Plus Propofol Plus Rococuronium Plus Isoflurane for Gynaecology Surgery in Cameroon Opiod Free Anesthesia - Opioids, Clinical Trial | Not applicable | Unknown | University of Yaounde 1 | 36 | 2020-01-06 | 2021-02-03 |
| Oxidative Balance in Opioid Therapy biochemical measurements - Pain, Opioids | Not applicable | Completed | Medical University of Bialystok | 50 | 2019-09-25 | 2021-02-18 |
| Safe Opioid Prescription Practice for Patients Discharged From Trauma Services safe opioid prescription protocol - Opioids, Drug Prescription | Not applicable | Unknown | Rhode Island Hospital | 300 | 2014-12-01 | 2015-10-23 |
| The Immune and Endocrine Systems in Chronic Non-cancer Patients Treated With Opioids Pain, Opioids | Completed | Copenhagen University Hospital, Rigshospitalet | 82 | 2014-09-01 | 2023-03-20 | |
| Quality of Telemedically Guided Prehospital Analgesia physician operated telemedical prehospital analgesia, prehospital analgesia by on-scene EMS physicians - Analgesia, Prehospital | Completed | RWTH Aachen University | 381 | 2014-01-01 | 2016-10-10 | |
| Attitudes Towards Buprenorphine and Methadone interview - Addictive, Opioids | Unknown | Psychiatric University Hospital, Zurich | 180 | 2009-05-01 | 2009-06-02 | |
| Morphine vs. Oxycodone for Postoperative Pain Management Morphine and oxycodone - Hysterectomy, Myoma | Phase 4 | Completed | Ullevaal University Hospital | 90 | 2007-09-01 | 2011-07-06 |
Agnosia (2) · Opioid-Related Disorders (2) · Pain (2) · Abdomen, Acute (1) · Chronic Pain (1) · Myoma (1) · Opiate Overdose (1) · Pain, Postoperative (1) · Respiratory Insufficiency (1) · Sleep Apnea, Obstructive (1)
Neurologic Manifestations (7) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Nervous System Diseases (3) · Pain (3) · Chemically-Induced Disorders (2) · Mental Disorders (2) · Narcotic-Related Disorders (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Respiration Disorders (2) · Respiratory Tract Diseases (2) · Substance-Related Disorders (2) · Abdominal Pain (1) · Apnea (1)
Acupuncture Therapy (1) · Anesthesia, General (1) · Interviews as Topic (1) · MoxDuo (1) · Transcutaneous Electric Nerve Stimulation (1)
Brigham and Women's Hospital (1) · Copenhagen University Hospital, Rigshospitalet (1) · Huazhong University of Science and Technology (1) · M.D. Anderson Cancer Center (1) · Medical University of Bialystok (1) · Prevention Strategies, LLC (1) · Psychiatric University Hospital, Zurich (1) · RWTH Aachen University (1) · Rhode Island Hospital (1) · The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (1) · Ullevaal University Hospital (1) · University of Chicago (1) · University of Pittsburgh (1) · University of Toronto (1) · University of Yaounde 1 (1)
United States (5) · Cameroon (1) · Canada (1) · China (1) · Germany (1) · Norway (1) · Poland (1) · Switzerland (1)
Danny J Eckert, PhD (1) · Jacqueline Ze Minkande, MD (1) · Joseph Arthur, MD (1) · Katherine Thompson, MD (1) · Lukas Boesch, PhD (1) · Mim Ari, MD (1) · Neda Laiteerapong, MD (1) · Rolf Rossaint, Professor, MD (1) · Sebastian Bergrath, MD (1) · Urszula Kosciuczuk (1) · Walid F Gellad, MD, MPH (1) · Wei Mei, MD (1) · Zhong Feng, Ph.D. (1)
PMID 19762758, PMID 30802933, PMID 31366330, PMID 35897111, PMID 36280804, PMID 42081274
R01DA044985 (1), R44DA050404 (1)